20193-20-8

Basic information

• Product Name: N-Ethylpropylamine
• Synonyms: N-ETHYLPROPYLAMINE;1-propanamine,N-ethyl;1-Propanamine,N-ethyl-;Ethylpropylamine;ethyl-propyl-amine;N,N-Ethylpropylamine;n-ethyl-1-propanamin;N-Ethyl-1-propanamine
• CAS NO: 20193-20-8
• Molecular Formula: C₅H₁₃N
• Molecular Weight: 87.16
• EINECS: 243-573-4
• Product Categories: Amines and Anilines;Polyamines
• Mol File: 20193-20-8.mol
• Article Data: 12

Chemical Properties

• Melting Point: -75°C (estimate)
• Boiling Point: 80-85°C
• Flash Point: 80-85°C
• Appearance: /Liquid
• Density: 0,72 g/cm3
• Vapor Pressure: 185mmHg at 25°C
• Refractive Index: 1.3950-1.3980
• Storage Temp.: Refrigerator
• Solubility: Chloroform, Ethyl Acetate
• PKA: 10.76±0.19(Predicted)
• CAS DataBase Reference: N-Ethylpropylamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-Ethylpropylamine(20193-20-8)
• EPA Substance Registry System: N-Ethylpropylamine(20193-20-8)

Safety Data

• Hazard Codes: F,T,C
• Statements: 34-11-37-35-24-20/22
• Safety Statements: 26-36/37/39-45-20
• RIDADR: 2735
• TSCA: Yes
• HazardClass: 3
• PackingGroup: II
• Hazardous Substances Data: 20193-20-8(Hazardous Substances Data)

Usage

Chemical Properties

Colourless Oil

Uses

N-Ethylpropylamine is used in the synthesis of neuraminidase inhibitors as well as non-peptide CRF-1 antagonists.

Flammability and Explosibility

Highlyflammable

InChI:InChI=1/C5H13N/c1-3-5-6-4-2/h6H,3-5H2,1-2H3/p+1

Upstream product

• 5339-67-3 N-ethylbenzenesulfonamide 
• 107-08-4 1-iodo-propane 
• 60-29-7 diethyl ether 
• 5129-72-6 N-ethylpropionamide 
• 7647-01-0 hydrogenchloride 
• 40548-47-8 N-ethyl-N-propyl-hydroxylamine 
• 7664-93-9 sulfuric acid 
• 71-23-8 propan-1-ol 
• 75-04-7 ethylamine 
• 5331-48-6 n-propylacetamide 
• 123-38-6 propionaldehyde 
• 27845-58-5 N-propylideneethylamine 
• 107-10-8 propylamine 
• 20577-33-7 ethylidene-propyl-amine 

Downstream Products

• 25413-61-0 ethyl-nitroso-propyl-amine 
• 78406-79-8 2,3-Bis-(ethyl-propyl-amino)-N-(4-methoxy-2-methyl-phenyl)-propionamide 
• 86684-77-7 3-(Ethyl-propyl-amino)-2,N-dimethyl-N-(3-phenyl-isoxazol-5-yl)-propionamide 
• 76-19-7 freon-218 
• 423-32-5 N,N-Difluor-heptafluor-n-propylamin 
• 206122-02-3 2-(3,5-di-t-butyl-4-hydroxyphenyl)-4-(2-(4-N-n-propyl-N-ethylaminomethylphenoxy)ethyl)oxazole hydrochloride 
• 286370-67-0 N'-{2-Chloro-4-[(6,7-dimethoxy-4-quinazolinyl)oxy]phenyl}-N-ethyl-N-propylurea 
• 1638-86-4 diethyl phenylphosphonite 
• 1519060-43-5 3-{[(16β,17β)-3-[(ethyl(propyl)amino)methyl]-17-hydroxyestra-1-(10),2,4-trien-16-yl]methyl}benzamide 
• 1218904-24-5 2-{5-[(7-{3-[ethyl(2-hydroxyethyl)amino]propoxy}quinazolin-4-yl)amino]-1H-pyrazol-3-yl}-N-(3-fluorophenyl)acetamide 
• 4682-26-2 2-(Ethyl-propyl-amino)-1-phenyl-propan-1-one 
• 141312-49-4 N-ethyl-2-phenyl-N-propylacetamide 
• 38529-20-3 benzothiazol-2-yl-{4-[2-(ethyl-propyl-amino)-ethoxy]-phenyl}-amine 
• 25675-87-0 Ethyl-propyl-dithiocarbamic acid 2,4-dinitro-phenyl ester 

Relevant articles and documents

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Catalytic hydrogenation of amides to amines under mild conditions

Under (not so much) pressure: A general method for the hydrogenation of tertiary and secondary amides to amines with excellent selectivity using a bimetallic Pd-Re catalyst has been developed. The reaction proceeds under low pressure and comparatively low temperature. This method provides organic chemists with a simple and reliable tool for the synthesis of amines. Copyright

METHOD FOR THE CONTINUOUS PRODUCTION OF AN AMINE

The invention relates to a method for the continuous production of an amine by reacting a primary or secondary alcohol, aldehyde and/or ketone with hydrogen and a nitrogen compound, selected from the group containing ammonia and primary and secondary amines, at a temperature that ranges between 60 and 300 °C in the presence of a catalyst containing copper. According to the invention, the catalytically active mass of the catalyst contains the following prior to its reduction with hydrogen: 20 to 85 wt. % aluminium oxide (Al2O3), zirconium dioxide (ZrO2), titanium dioxide (TiO2) and/or silicon dioxide (SiO2); 1 to 70 wt. % copper compounds containing oxygen, calculated as CuO; 0 to 50 wt. % magnesium compounds containing oxygen, calculated as MgO; chromium compounds containing oxygen, calculated as Cr2O3; zinc compounds containing oxygen, calculated as ZnO; barium compounds containing oxygen, calculated as BaO; and/or calcium compounds containing oxygen, calculated as CaO; and less than 30 wt. % nickel compounds containing oxygen, calculated as NiO, in relation to the copper compounds containing oxygen, calculated as CuO. The reaction in the gas phase takes place isothermally in a tubular reactor.