1953-56-6

Basic information

• Product Name: (E)-2-Butene-1,4-diol di(methanesulfonate)
• Synonyms: (E)-2-Butene-1,4-diol bis(methanesulfonate);(E)-2-Butene-1,4-diol di(methanesulfonate);CB-2095;Di(methanesulfonic acid)(E)-2-butenylene ester
• CAS NO: 1953-56-6
• Molecular Formula: C₆H₁₂O₆S₂
• Molecular Weight: 244.30
• Mol File: 1953-56-6.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 134.5°C
• Flash Point: 239.3°C
• Appearance: /
• Density: 1.359 (estimate)
• Vapor Pressure: 1.26E-08mmHg at 25°C
• Refractive Index: 1.5630 (estimate)
• CAS DataBase Reference: (E)-2-Butene-1,4-diol di(methanesulfonate)(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-2-Butene-1,4-diol di(methanesulfonate)(1953-56-6)
• EPA Substance Registry System: (E)-2-Butene-1,4-diol di(methanesulfonate)(1953-56-6)

Safety Data

• Hazardous Substances Data: 1953-56-6(Hazardous Substances Data)

Usage

General Description

(E)-2-Butene-1,4-diol di(methanesulfonate) is a chemical compound consisting of two methanesulfonate groups attached to the 2,4 positions of a 2-butene-1,4-diol molecule. It is commonly used as a reagent in organic synthesis and as a building block for the preparation of various compounds. The methanesulfonate groups can act as good leaving groups, making this compound useful in the protection and deprotection of hydroxyl groups in organic reactions. Additionally, it can be used in the synthesis of bioactive molecules, pharmaceuticals, and materials. The compound is typically handled and stored as a solid and should be kept in a cool, dry place away from heat and flame. As with all chemical compounds, proper safety precautions should be taken when handling and using (E)-2-Butene-1,4-diol di(methanesulfonate).

InChI:InChI=1/C6H12O6S2/c1-13(7,8)11-5-3-4-6-12-14(2,9)10/h3-4H,5-6H2,1-2H3/b4-3+

Upstream product

• 821-11-4 trans-butene-1,4-diol 
• 124-63-0 methanesulfonyl chloride 
• 6117-80-2 1,4-butenediol 

Downstream Products

• 1476-11-5 Z-1,4-dichlorobutene 
• 6845-82-5 N-(β-Phenylethyl)-Δ³-pyrrolin 
• 6913-92-4 1-benzyl-2,5-dihydro-1H-pyrrole 
• 163776-49-6 methyl 2-(3,4-dihydro)pyrrolidinophenylacetate 
• 464174-43-4 1-(3-bromophenyl)-2,5-dihydropyrrole 
• 199532-83-7 ethyl 1-((4-bromobenzylidene)amino)cyclopent-3-ene-1-carboxylate 
• 200122-28-7 (1R,2S,5R)-menthyl 2-(3,4-dihydro)pyrrolidinophenylacetate 
• 199532-88-2 ethyl 1-aminocyclopent-3-ene-1-carboxylate 
• 213316-32-6 rac-(1R,2S)-1-amino-2-vinylcyclopropanecarboxylic acid ethyl ester 
• 127839-96-7 1-(2-Chloro-6-methyl-phenyl)-2,5-dihydro-1H-pyrrole 
• 103204-12-2 1-phenyl-2,5-dihydro-1H-pyrrole 
• 68109-75-1 1-cyclohexyl-2,5-dihydro-1H-pyrrole 
• 6892-53-1 (Z)-1,4-bis(4-nitrophenoxy)but-2-ene 
• 6728-07-0 1,4-Bis-<4-nitro-phenoxy>-but-2t-en 

Relevant articles and documents

Formal [5+1] annulation reactions of dielectrophilic peroxides: Facile access to functionalized dihydropyrans

A general [5+1] annulation reaction, which utilized 4-bromo- or 4-mesyloxy-but-2-enyl peroxides as unique five-atom bielectrophilic synthons to participate in the C-C and the subsequent umpolung C-O bond-forming reactions with C1 nucleophiles, has been developed for the facile synthesis of 2,2-disubstituted dihydropyrans in high yields under mild basic conditions. The dihydropyrans, which are readily prepared on a gram scale by this new method, can be flexibly transformed into the biologically important tetrahydropyrans and pyranones in 1-2 steps.

CHIRAL CONTROL

The present invention relates to chirally controlled oligonucleotides, chirally controlled oligonucleotide compositions, and the method of making and using the same.

3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS

The present invention relates to 3-azabicyclo[3.1.0]hexane derivatives, which are useful as vanilloid receptor (VR) ligands, methods of treating diseases, conditions and/or disorders modulated by vanilloid receptors with them, and processes for preparing them.