6913-92-4

Basic information

• Product Name: 1-Benzyl-2,5-dihydro-1H-pyrrole
• Synonyms: N-BENZYLPYRROLINE;1-BENZYL-3-PYRROLINE;BPL;N-BENZYL-3-PYRROLINE;1-Benzyl-3-pyrrolidon;1-benzyl-2,5-dihydro-1H-pyrrole;1-Benzyl-3-pyrroline, 98+%;1-(Phenylmethyl)-2,5-dihydropyrrole
• CAS NO: 6913-92-4
• Molecular Formula: C₁₁H₁₃N
• Molecular Weight: 159.23
• EINECS: -0
• Product Categories: pharmacetical;Building Blocks;Heterocyclic Building Blocks;Pyrrolines
• Mol File: 6913-92-4.mol
• Article Data: 28

Chemical Properties

• Boiling Point: 60 °C1 mm Hg(lit.)
• Flash Point: 198 °F
• Appearance: Colorless to pale yellow/Liquid
• Density: 0.837 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.083mmHg at 25°C
• Refractive Index: n20/D 1.542(lit.)
• Storage Temp.: Sealed in dry,Store in freezer, under -20°C
• PKA: 8.95±0.50(Predicted)
• Sensitive: Air Sensitive
• BRN: 111101
• CAS DataBase Reference: 1-Benzyl-2,5-dihydro-1H-pyrrole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Benzyl-2,5-dihydro-1H-pyrrole(6913-92-4)
• EPA Substance Registry System: 1-Benzyl-2,5-dihydro-1H-pyrrole(6913-92-4)

Safety Data

• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-27-36/37/39-45-20
• RIDADR: UN 3267 8/PG 2
• WGK Germany: 3
• HazardClass: 8
• PackingGroup: III
• Hazardous Substances Data: 6913-92-4(Hazardous Substances Data)

Usage

Uses

1-Benzyl-3-pyrroline was used in synthesis of (S)-1-benzyl-3-hydroxypyrrolidine.

InChI:InChI=1/C11H13N/c1-2-6-11(7-3-1)10-12-8-4-5-9-12/h1-7H,8-10H2

Upstream product

• 109-96-6 3-Pyrroline 
• 109-97-7 pyrrole 
• 98-88-4 benzoyl chloride 
• 4383-26-0 N,N-di-2-propenylbenzylamine 
• 100-46-9 benzylamine 
• 31410-11-4 N-benzyl-N-(but-2-en-1-yl)but-2-en-1-amine 
• 124-38-9 carbon dioxide 
• 70882-08-5 N-benzylbuta-2,3-dien-1-amine 
• 1197-51-9 N-propargylbenzylamine 
• 100-44-7 benzyl chloride 
• 50-00-0 formaldehyd 
• 100-39-0 benzyl bromide 
• 1953-56-6 (Z)-but-2-ene-1,4-diyl dimethanesulfonate 
• 1476-11-5 Z-1,4-dichlorobutene 

Downstream Products

• 2051-97-0 1-benzyl-1H-pyrrole 
• 101385-90-4 (S)-N-benzyl-3-hydroxypyrrolidine 
• 101385-90-4 (R)-N-benzyl-3-hydroxypyrrolidine 
• 775-15-5 1-benzyl-3-pyrrolidinol 
• 162108-77-2 N-Benzyl-Δ³-pyrrolin-N-oxid 
• 75390-09-9 3-benzyl-6-oxa-3-azabicyclo[3.1.0]-hexane 
• 29897-82-3 N-benzylpyrrolidine 
• 1028289-32-8 benzyl-(2-sec-butyl-but-3-enyl)-amine 
• 63468-63-3 2,5-dihydro-1H-pyrrole hydrochloride 
• 848472-13-9 tert-butyl (+/-)-6-[(1'-benzyl-4'-oxopyrrolidin-3'-yl)methyl]pyridin-2-ylcarbamate 

Relevant articles and documents

Vanadium Imido NHC Complexes for Ring-Closing Olefin Metathesis Reactions

Vanadium bis-phosphine imido and oxo chloride alkylidenes have been extensively applied in the ring-closing metathesis of various acyclic olefins. However, their reactions involving ethylene have shown limited productivity due to rapid decomposition. The

Preparation method of medical intermediate N-benzyl-3-pyrroline

The invention discloses a preparation method of a medical intermediate N-benzyl-3-pyrroline. The method comprises the following steps: adding a proper amount of benzylamine, maleic anhydride and a reaction medium into a reaction flask, and stirring for reaction to obtain a diamide compound; and dissolving a diamide compound in tetrahydrofuran, dropwise adding a proper amount of 70% red aluminum solution, and reducing the diamide compound to obtain N-benzyl-3-pyrroline; The method is low in raw material cost, simple in process step, high in yield, small in pollution, high in product purity and suitable for industrial production.

Molybdenum Benzylidyne Complexes for Olefin Metathesis Reactions

The molybdenum benzylidynes [ArCMo(OC(CF3)2CH3)3(1,2-dimethoxyethane)], where Ar = Ph (2a), p-(OCH3)C6H4 (2b), p-(CF3)C6H4 (2c), p-(NO2)C6H4 (2d), or 4-(NO2)-3-(CF3)C6H3 (2e), and [p-(NO2)C6H4CMo(OC(CF3)2CH3)3] (2f) catalyze the ring-closing metathesis (RCM) reaction of diallyl N-tosylamide (3) to produce 1-tosyl-2,5-dihydro-1H-pyrrole (4) and ethylene. The scope of RCM catalytic activity of 2e, cross-metathesis of 1-hexene, and ring-opening metathesis polymerization of cyclooctene were explored. The X-ray crystal structure of 2e was determined. Variable-temperature 1H NMR spectra revealed the formation of intermediates during the reaction of 3 with 2f and the reforming of 2f after completion of the reaction. The use of 13C-labeled Mo benzylidyne did not show transfer of the carbon atom next to Mo to any of the products.