197902-92-4

Upstream product

• 197902-91-3 (2S)-2-phthalimido-6-hydroxyheptanoic acid, phenylmethyl ester 
• 84688-13-1 (S)-2-phthalimido-6-hydroxyhexanoic acid, phenylmethyl ester 
• 84688-14-2 benzyl (S)-2-(1,3-dioxoisoindolin-2-yl)-6-oxohexanoate 
• 84688-11-9 (S)-2-(1,3-dioxoisoindolin-2-yl)-6-hydroxyhexanoic acid 
• 100-39-0 benzyl bromide 
• 917-54-4 methyllithium 
• 182886-36-8 (S)-2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-6-oxo-heptanoic acid benzyl ester 

Downstream Products

• 197902-93-5 (S)-2-phthalimido-6-methyl-6-azidoheptanoic acid, phenylmethyl ester 
• 182886-83-5 (S)-hexahydro-7,7-dimethyl-3-<(triphenylmethyl)amino>-2H-azepin-2-one 
• 160135-92-2 [14C]-Gemopatrilat 
• 160135-15-9 [S-(R*,R*)]-Hexahydro-6-[[2-(acetylthio)-1-oxo-3-phenylpropyl]amino]-2,2-dimethyl-7-oxo-1H-azepine-1-acetic acid, ethyl ester 
• 182886-84-6 (S)-Hexahydro-6-[(triphenylmethyl)amino]-2,2-dimethyl-7-oxo-1H-azepine-1-acetic acid, ethyl ester 

Relevant academic research and scientific papers

Vasopeptidase inhibitors: Incorporation of geminal and spirocyclic substituted azepinones in mercaptoacyl dipeptides

A series of 7-(di)alkyl and spirocyclic substituted azepinones were generated and incorporated as conformationally restricted dipeptide surrogates in mercaptoacyl dipeptides. Clear structure-activity relationships with respect to both angiotensin-converti