1989-25-9

Usage

InChI:InChI=1/C9H11ClO/c1-9(2,11)7-3-5-8(10)6-4-7/h3-6,11H,1-2H3

Upstream product

• 873-77-8 (4-chlorphenyl)magnesium bromide 
• 67-64-1 acetone 
• 106-39-8 bromochlorobenzene 
• 34386-95-3 tert-butyl p-chloro-α,α-dimethylbenzyl peroxide 
• 2747-38-8 methyltrichlorotitanium 
• 99-91-2 para-chloroacetophenone 
• 917-54-4 methyllithium 
• 122-01-0 4-chloro-benzoyl chloride 
• 74-83-9 methyl bromide 
• 7335-27-5 ethyl 4-chlorobenzoate 
• 74-88-4 methyl iodide 
• 2621-46-7 1-chloro-4-isopropylbenzene 
• 617-94-7 1-methyl-1-phenylethyl alcohol 
• 75-16-1 methylmagnesium bromide 

Downstream Products

• 31220-69-6 N-[1-(4-chlorophenyl)-1-methylethyl]-acrylamide 
• 64798-38-5 1-chloro-4-(1-isocyanato-1-methylethyl)benzene 
• 41912-29-2 1-(4-chlorophenyl)-1-methylethylium 
• 23852-78-0 4-Nitro-benzoic acid 1-(4-chloro-phenyl)-1-methyl-ethyl ester 
• 28094-77-1 5-chloro-3-(4-chlorophenyl)-1,1,3-trimethyl-2,3-dihydro-1H-indene 
• 98-82-8 Isopropylbenzene 
• 1712-70-5 1-chloro-4-(1-methylethenyl)-benzene 
• 17797-11-4 1-(4-chlorophenyl)-1-methylethylamine 
• 1293965-61-3 2-[(2-(4-chlorophenyl)prop-2-yl)sulfanyl]-5-(4-methoxyphenyl)-4-methylthiazole-N-oxide 
• 99-91-2 para-chloroacetophenone 
• 37446-15-4 1-[1-(4-Chloro-phenyl)-1-methyl-ethoxy]-2,4-dinitro-benzene 

Relevant academic research and scientific papers

Stepwise benzylic oxygenation via uranyl-photocatalysis

Stepwise oxygenation at the benzylic position (1°, 2°, 3°) of aromatic molecules was comprehensively established under ambient conditions via uranyl photocatalysis to produce carboxylic acids, ketones, and alcohols, respectively. The accuracy of the stepwise oxygenation was ensured by the tunability of catalytic activity in uranyl photocatalysis, which was adjusted by solvents and additives demonstrated through Stern–Volmer analysis. Hydrogen atom transfer between the benzylic position and the uranyl catalyst facilitated oxygenation, further confirmed by kinetic studies. Considerably improved efficiency of flow operation demonstrated the potential for industrial synthetic application.

LIGHT INDUCED CATALYTIC C-H OXYGENATION OF ALKANES

A method of oxygenating a benzylic C-H bond is provided. The method comprises light induced activation of an initiator and subsequent reaction with oxygen, resulting in the formation of free radicals. Subsequently, free radicals catalyze the reaction of the benzylic C-H bond with oxygen, thereby forming an oxygenated compound.

Isopropanol as a hydrogen source for single atom cobalt-catalyzed Wacker-type oxidation

The first example of a heterogeneous cobalt catalytic system for Wacker-type oxidation catalyzed by a single atom dispersed Co-N/C catalyst using alcohol as the hydrogen source under an oxygen atmosphere is presented. By combining a well-designed, controlled experiment and various methods of characterization, we determined that single atom cobalt was the active center rather than nanoparticle or oxide counterparts.

CARBAZOLE BASED COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME

The present specification provides a carbazole-based compound represented by chemical formula 1, and an organic light-emitting device comprising the same. According to one embodiment of the present specification, the compound may be used as a material for an organic material layer in an organic light-emitting device to improve efficiency, lower driving voltage, and/or improve lifetime characteristics of the device. Additionally, another embodiment of the present specification provides an organic light-emitting device which comprises: a first electrode; a second electrode disposed to face the first electrode; and one or more organic material layers disposed between the first electrode and the second electrode, wherein at least one of the organic layer materials comprises a compound represented by the chemical formula 1.COPYRIGHT KIPO 2017

NEW COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME

The present specification provides a compound represented by chemical formula 1, and an organic light-emitting device comprising the same. The compound of the present specification may be used as a material for an organic material layer in an organic light-emitting device to improve efficiency, low driving voltage, and lifetime characteristics of the organic light-emitting device. Additionally, the present specification provides an organic light-emitting device which comprises: a first electrode; a second electrode facing the first electrode; and one or more organic material layers disposed between the first electrode and the second electrode, wherein at least one of the organic material layers comprises the compound of the present specification.COPYRIGHT KIPO 2017

Selective reaction of benzyl alcohols with HI gas: Iodination, reduction, and indane ring formations

Reactions of benzyl alcohols with HI in solvent-free conditions were examined. Three types of reactions (iodination, reduction, and ring formation) occurred depending on the degree of crowding around the benzyl position and the benzylic stabilization of substrates. Results also showed that the ring formation to give indanes proceeded efficiently when HI was used, and that compounds with electron-rich aromatic rings gave indane derivatives in good yields.

Room temperature C(sp2)-H oxidative chlorination: Via photoredox catalysis

Photoredox catalysis has been developed to achieve oxidative C-H chlorination of aromatic compounds using NaCl as the chlorine source and Na2S2O8 as the oxidant. The reactions occur at room temperature and exhibit exclusive selectivity for C(sp2)-H bonds over C(sp3)-H bonds. The method has been used for the chlorination of a diverse set of substrates, including the expedited synthesis of key intermediates to bioactive compounds and a drug.

IMIDAZO [1,5-A]PYRIMIDINYL CARBOXAMIDE COMPOUNDS AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS

The invention provides substituted imidazo[1,5-a]pyrimidinyl carboxamide and related organic compounds, compositions containing such compounds, medical kits, and methods for using such compounds and compositions to treat medical disorders, e.g., Gaucher disease, Parkinson's disease, Lewy body disease, dementia, or multiple system atrophy, in a patient. Exemplary substituted imidazo[1,5-a]pyrimidinyl carboxamide compounds described herein include substituted 2-heterocyclyl-4-alkyl-imidazo[1,5-a]pyrirnidine-8-carboxamide compounds and variants thereof.

PYRROLO[1,2-A]PYRIMIDINYL CARBOXAMIDE COMPOUNDS AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS

The invention provides substituted pyrrolo[1,2-a]pyrimidinyl carboxamide and related organic compounds, compositions containing such compounds, medical kits, and methods for using such compounds and compositions to treat medical disorders, e.g., Gaucher disease, Parkinson's disease, Lewy body disease, dementia, or multiple system atrophy, in a patient. Exemplary substituted pyrrolo[1,2-a]pyrimidinyl carboxamide compounds described herein include substituted 2-heterocyclyl-4-alkyl-pyrrolo[1,2-a]pyrimidine-8-carboxarnide compounds and variants thereof.

PYRAZOLO[1,5-A]PYRIMIDINYL CARBOXAMIDE COMPOUNDS AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS

The invention provides substituted pyrazolo[1,5-a]pyrimidinyl carboxamide and related organic compounds, compositions containing such compounds, medical kits, and methods for using such compounds and compositions to treat medical disorders, e.g., Gaucher disease, Parkinson's disease, Lewy body disease, dementia, or multiple system atrophy, in a patient. Exemplary substituted pyrazolo[1,5-a]pyrimidinyl carboxamide compounds described herein include 2-heterocyclyl-4-alkyl-pyrazolo[1,5-a]pyrirnidine-3-carboxarnide compounds and variants thereof.