21969-10-8

Basic information

• Product Name: 4-cyanophenyl 4′-nitrophenyl sulfide
• Synonyms: 4-cyanophenyl 4′-nitrophenyl sulfide
• CAS NO: 21969-10-8
• Molecular Weight: 256.285
• Mol File: 21969-10-8.mol

Chemical Properties

• CAS DataBase Reference: 4-cyanophenyl 4′-nitrophenyl sulfide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-cyanophenyl 4′-nitrophenyl sulfide(21969-10-8)
• EPA Substance Registry System: 4-cyanophenyl 4′-nitrophenyl sulfide(21969-10-8)

Safety Data

• Hazardous Substances Data: 21969-10-8(Hazardous Substances Data)

Upstream product

• 1223-31-0 bis(4-nitrophenyl)sulfide 
• 61628-44-2 sodium 4-cyanobenzenethiolate 
• 100-00-5 4-chlorobenzonitrile 
• 36801-01-1 4-cyanobenzenethiol 
• 100-32-3 di(p-nitrophenyl) disulfide 
• 2863-98-1 4-hydrazinobenzonitrile hydrochloride 
• 623-03-0 4-Cyanochlorobenzene 
• 1849-36-1 para-nitrobenzenethiol 
• 46836-99-1 bis(4-cyanophenyl)sulfide 
• 13113-79-6 sodium 4-nitrobenzenethiolate 

Downstream Products

• 61628-44-2 sodium 4-cyanobenzenethiolate 
• 1425187-91-2 4-cyanophenyl(4'-nitrophenyl)sulfoxide 
• 16447-86-2 4-<18F>-fluoronitrobenzene 
• 101533-61-3 4-(4-nitrobenzenesulfonyl)benzonitrile 
• 101533-57-7 4-(4-aminobenzenesulfonyl)benzonitrile 
• 46836-99-1 bis(4-cyanophenyl)sulfide 

Relevant articles and documents

SMALL MOLECULE ACTIVATORS OF NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT) AND USES THEREOF

Provided herein are small molecule activators of Nicotinamide Phosphoribosyltransferase (NAMPT), compositions comprising the compounds, and methods of using the compounds and compositions.

Transition-Metal-Free and Oxidant-Free Cross-Coupling of Arylhydrazines with Disulfides: Base-Promoted Synthesis of Unsymmetrical Aryl Sulfides

A novel synthesis of unsymmetrical aryl sulfides, which requires no transition metal catalyst and no oxidant, was developed. This base-promoted cross-coupling reaction proceeded using arylhydrazines and 1 equiv amount of disulfides under inert gas conditions to afford the unsymmetrical aryl sulfides in good yields.

No-carrier-added [18F]fluoroarenes from the radiofluorination of diaryl sulfoxides

No-carrier-added [18F]fluoroarenes were synthesized through the radiofluorination of diaryl sulfoxides with [18F]fluoride ion. Diaryl sulfoxides bearing a para electron-withdrawing substituent readily gave the corresponding 4-[18F]fluoroarenes in high RCYs. This process broadens the scope for preparing novel 18F-labeling synthons and PET radiotracers.

Diaryl Sulfide Cleavage by Sodium Sulfide in Dipolar Aprotic Solvents

The interaction of sodium sulfide with diaryl sulfides that possess electron-withdrawing substituents (e. g., cyano or nitro) on the aromatic rings results in cleavage of the thioether and the formation of sodium aryl sulfides in dipolar aprotic solvents.Exchange reactions between these diaryl sulfides and sodium aryl sulfides are also observed in dipolar aprotic solvents.The cleavage and exchange reactions were employed to prepare mixed diaryl or alkyl aryl sulfides from symmetrical diaryl sulfides.