22409-91-2 Usage
Description
ETHYL 3-PHENOXYPROPIONATE is an organic compound that serves as a synthetic intermediate in the chemical industry. It is characterized by its ester functional group and is derived from the reaction of phenol with propionic acid. ETHYL 3-PHENOXYPROPIONATE is known for its ability to be further transformed into various other chemical compounds, making it a versatile building block in organic synthesis.
Uses
Used in Pharmaceutical Industry:
ETHYL 3-PHENOXYPROPIONATE is used as a synthetic intermediate for the preparation of Phenoxypropionic acids, which are a class of nonsteroidal anti-inflammatory drugs (NSAIDs). These NSAIDs are widely used for their analgesic, antipyretic, and anti-inflammatory properties, helping to alleviate pain and reduce inflammation in various conditions.
Used in Chemical Industry:
In the chemical industry, ETHYL 3-PHENOXYPROPIONATE is utilized as a synthetic intermediate for the production of Chromanone derivatives. Chromanone derivatives are important compounds with a wide range of applications, including pharmaceuticals, agrochemicals, and materials science. They exhibit various biological activities, such as antioxidant, anti-inflammatory, and anticancer properties, making them valuable for the development of new drugs and other products.
Used in Research and Development:
ETHYL 3-PHENOXYPROPIONATE is also used in research and development for the synthesis of novel compounds with potential applications in various fields. Its reactivity and versatility make it an attractive candidate for the development of new chemical entities, which could lead to the discovery of new drugs, materials, or other useful products.
Check Digit Verification of cas no
The CAS Registry Mumber 22409-91-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,2,4,0 and 9 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 22409-91:
(7*2)+(6*2)+(5*4)+(4*0)+(3*9)+(2*9)+(1*1)=92
92 % 10 = 2
So 22409-91-2 is a valid CAS Registry Number.
InChI:InChI=1/C11H14O3/c1-2-13-11(12)8-9-14-10-6-4-3-5-7-10/h3-7H,2,8-9H2,1H3
22409-91-2Relevant articles and documents
The synthesis and evaluation of phenoxyacylhydroxamic acids as potential agents for Helicobacter pylori infections
Ni, Wei-Wei,Liu, Qi,Ren, Shen-Zhen,Li, Wei-Yi,Yi, Li-Li,Jing, Heng,Sheng, Li-Xin,Wan, Qin,Zhong, Ping-Fu,Fang, Hai-Lian,Ouyang, Hui,Xiao, Zhu-Ping,Zhu, Hai-Liang
supporting information, p. 4145 - 4152 (2018/07/13)
Two series of ω-phenoxy contained acylhydroxamic acids as novel urease inhibitors were designed and synthesized. Biological activity evaluations revealed that ω-phenoxypropinoylhydroxamic acids were more active than phenoxyacetohydroxamic acids. Out of these compounds, 3-(3,4-dichlorophenoxy)propionylhydroxamic acid c24 showed significant potency against urease in both cell free extract (IC50 = 0.061 ± 0.003 μM) and intact cell (IC50 = 0.89 ± 0.05 μM), being over 450- and 120-fold more potent than the clinically prescribed urease inhibitor AHA, repectively. Non-linear fitting of experimental data (V-[S]) suggested a mixed-type inhibition mechanism and a dual site binding mode of these compounds.
Kinetics and mechanism of thermal gas-phase elimination of β-substituted carboxylic acids
Al-Awadi,Abdallah,Dib,Ibrahim,Al-Awadi,El-Dusouqui
, p. 5769 - 5777 (2007/10/03)
3-Phenoxypropanoic acid (1), 3-(phenylthio)propanoic acid (2), and 4-phenylbutanoic acid (3) were pyrolysed between 520 and 682 K. Analysis of the pyrolysates showed the elimination products to be acrylic acid and the corresponding arene. Pyrolysis of ethyl 3-phenoxypropanoate (4) and its methyl analogue (5), ethyl 3-(phenylthio)propanoate (6) and its methyl counterpart (7), and 3-phenoxypropane nitrile (8) were also investigated between 617 and 737 K. The thermal gas-phase elimination kinetics and product analysis are compatible with a thermal retro-Michael reaction pathway involving a four-membered cyclic transition state.
