22482-62-8

Upstream product

• 124-38-9 carbon dioxide 
• 100-40-3 4-ethenylcyclohexene 
• 978-70-1 tris<2-(3-cyclohexen-1-yl)ethyl>aluminum 
• 16626-54-3 3-cyclohex-3-enylpropan-1-ol 
• 22482-61-7 2-(3-Cyclohexen-1-yl)-ethan-1,1-dicarbonsaeure 
• 67-66-3 chloroform 
• 88686-86-6 2-<2-(3-Cyclohexen-1-yl)ethyl>-1,3,2-dithiaborolane 
• 72581-32-9 cyclohex-3-enylmethanol 
• 22482-60-6 Diethyl-2-(3-cyclohexen-1-yl)-ethan-1,1-dicarboxylat 
• 201230-82-2 carbon monoxide 

Downstream Products

• 22482-52-6 3-(3-Cyclohexen-1-yl)-propionsaeurechlorid 
• 389607-96-9 3-(cyclohex-3-en-1-yl)-1-phenyl-1-propanone 
• 280-65-9 bicyclo[3.3.1]nonane 
• 6671-66-5 bicyclo[3.3.1]non-2-ene 
• 2568-17-4 bicyclo[3.3.1]nonan-2-one 
• 22858-74-8 3-(cyclohex-3-en-1-yl)propanal 
• 16626-54-3 3-cyclohex-3-enylpropan-1-ol 
• 20681-51-0 methyl 3-cyclohexylpropionate 
• 1124-63-6 3-cyclohexylpropan-1-ol 
• 120264-01-9 3-Cyclohex-3-enyl-2-diazo-propionic acid methyl ester 
• 120264-02-0 (propene-2 oate de methyle) yl-4 cyclohexene cis 
• 78640-15-0 3-(3-Cyclohexen-1-yl)propansaeure-methylester 

Relevant academic research and scientific papers

A direct synthesis of carboxylic acidsviaplatinum-catalysed hydroxycarbonylation of olefins

The platinum-catalysed hydroxycarbonylation of olefins is reported for the first time. Using a combination of PtCl2/2,2′-bis(tert-butyl(pyridin-2-yl)phosphanyl)-1,1′-binaphthalene (Neolephos) in the presence of sulfuric acid [0.6 M] in acetic acid selective carbonylation of terminal aliphatic olefins proceeds to good yields and selectivities to the corresponding carboxylic acids. Comparing the reactivity of different butenes (iso- andn-butenes), the terminal olefin can be selectively carbonylated.

Cp2TiCl2-Catalyzed Regioselective Hydrocarboxylation of Alkenes with CO2

Cp2TiCl2-catalyzed regioselective hydrocarboxylation of alkenes with CO2 to give carboxylic acids in high yields has been developed in the presence of iPrMgCl. The reaction proceeds with a wide range of alkenes under mild conditions. Styrene and its derivatives can transform to α-aryl carboxylic acids, and aliphatic alkenes can transform to form alkanoic acids.

Organoboranes. 35. Reaction of Alkylthioboronic Esters with Trichloromethyllithium: Preparation of One-Carbon-Extended Carboxylic Acids and Thioacetals from Alkenes via Hydroboration

Various 2-alkyl-1,3,2-dithiaborolanes, RB(S2C2H4) (1), were converted to the corresponding carboxylic acids, RCO2H (2), by using LiCCl3 in THF, followed by oxidation with alkaline hydrogen peroxide.For R=hexyl, a reaction intermediate is converted by solvent into another compound, C6H13C(S2C2H4)B2 (9a), characterized spectroscopically.The yields of 2 decreased with increasing bulkiness of the alkyl groups R.Although the configuration of R= trans-2-methylcyclopent-1-yl (1k) was retained in the product (>98percent trans), a significant degree of epimerization tookplace for R= exo-norbornyl (1j) during the oxidation (exo : endo = 86 : 14).More uniquely, the intermediates 9 were easily hydrolyzed by heating the reaction mixture with aqueous NaOH to give the corresponding 2-alkyl-1,3-dithiolanes 3.Stereochemical integrity was retained in the products derived from 1j and 1k.Since 1 was prepared by the hydroboration of alkenes, this sequence provides a new method for introducing oxycarbonyl or thioacetal functionality into alkenes in a regioselective manner, and, in the case of 3, also with stereocontrol.