2308-61-4

Basic information

• Product Name: 3,6-Dibenzylhexahydropyrazine-2,5-dione
• Synonyms: 3,6-Bis(phenylmethyl)-2,5-piperazinedione;3,6-Dibenzyl-2,5-piperazinedione;3,6-Dibenzylhexahydropyrazine-2,5-dione
• CAS NO: 2308-61-4
• Molecular Formula: C₁₈H₁₈N₂O₂
• Molecular Weight: 294.3477
• Mol File: 2308-61-4.mol
• Article Data: 7

Chemical Properties

• Melting Point: 289-291 °C(Solv: ethanol (64-17-5))
• Boiling Point: 594.2°Cat760mmHg
• Flash Point: 229.8°C
• Appearance: /
• Density: 1.186g/cm³
• Vapor Pressure: 4.34E-14mmHg at 25°C
• Refractive Index: 1.59
• PKA: 12.88±0.60(Predicted)
• CAS DataBase Reference: 3,6-Dibenzylhexahydropyrazine-2,5-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 3,6-Dibenzylhexahydropyrazine-2,5-dione(2308-61-4)
• EPA Substance Registry System: 3,6-Dibenzylhexahydropyrazine-2,5-dione(2308-61-4)

Safety Data

• Hazardous Substances Data: 2308-61-4(Hazardous Substances Data)

Usage

Uses

3,6-Dibenzylpiperazine-2,5-dione is a new class of anthelmintics. 3,6-Dibenzylpiperazine-2,5-dione is a dipeptide metabolites from the broth of marine fungus Aspergillus specie. 3,6-Dibenzylpiperazine-2,5-dione is a secondary metabolites of Aspergillus awamori F12 isolated from rhizosphere soil of Rhizophora stylosa Griff that exhibits antibacterial properties.

InChI:InChI=1/C18H18N2O2/c21-17-15(11-13-7-3-1-4-8-13)19-18(22)16(20-17)12-14-9-5-2-6-10-14/h1-10,15-16H,11-12H2,(H,19,22)(H,20,21)/t15-,16-/m1/s1

Upstream product

• 150-30-1 Phenylalanine 
• 63-91-2 L-phenylalanine 
• 1233-98-3 3,6-dibenzylidene-2,5-piperazinedione 
• 64-19-7 acetic acid 
• 60-29-7 diethyl ether 
• 64-17-5 ethanol 
• 508220-75-5 2-azidocarbonyl-3-phenyl-propionic acid 
• 100-52-7 benzaldehyde 
• 2308-61-4 3,6-dibenzylpiperazine-2,5-dione 
• 3182-93-2 (L)-phenylalanine ethyl ester hydrochloride 
• 1795-96-6 phenylalanine ethyl ester 
• 74720-33-5 (Z)-3-(Z)-6-dibenzylidene-2,5-piperazinedione 
• 15028-44-1 DL-phenylalanine methyl ester 
• 126727-04-6 2-(9-fluorenylmethoxycarbonylamino)-3-phenylpropionic acid 

Downstream Products

• 103511-63-3 3,6-dibenzyl-1,4-bis-(N,N-phthaloyl-glycyl)-piperazine-2,5-dione 
• 94514-47-3 (+/-)-trans-1,4-diacetyl-3,6-dibenzylpiperazine-2,5-dione 
• 59552-68-0 (+/-)-cis-1,4-diacetyl-3,6-dibenzylpiperazine-2,5-dione 
• 13795-55-6 (+/-)-cis-3,6-dibenzyl-1,4-dimethylpiperazine-2,5-dione 
• 61139-44-4 cyclo-L-N-methylphenylalanyl-D-N-methylphenylalanyl 
• 132213-60-6 3,6-dibenzyl-5-chloropyrazine 
• 74156-60-8 3,6-dibenzyl-2,5-dichloropyrazine 
• 133357-48-9 3,6-dibenzyl-2-benzyloxy-5-methoxypyrazine 4-oxide 
• 132213-67-3 3,6-dibenzyl-2-benzyloxy-5-methoxypyrazine 1-oxide 
• 132213-66-2 3,6-dibenzyl-2-benzyloxy-5-methoxypyrazine 
• 132213-63-9 6-(α-acetoxybenzyl)-3-benzyl-5-methoxypyrazine 
• 132213-64-0 2-acetoxy-3,6-dibenzyl-5-methoxypyrazine 
• 117333-12-7 emeheterone 
• 132213-59-3 3,6-dibenzyl-2-hydroxy-5-methoxypyrazine 1-oxide 

Relevant articles and documents

Towards structure determination of self-assembled peptides using dynamic nuclear polarization enhanced solid-state NMR spectroscopy

Supra-sensitivity: Dynamic nuclear polarization (DNP) enhanced solid-state NMR spectroscopy was performed on self-assembled peptide nanotubes. This approach yields significant experimental time savings (about five orders of magnitude; see picture) and was

Investigation of reaction mechanism of amino acids and phosphorus trichloride by 31P NMR and ESI-MS/MS

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Amino Acid Derivatives in Organic Synthesis: New Synthetic Routes to Heterocycles Containing Amino Acid Residues

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