23133-34-8Relevant academic research and scientific papers
Microwave-mediated Green synthesis of oxadiazole derivatives against inflammatory disease
Sahoo, Biswa Mohan,Panda, Jnyanaranjan,Banik, Bimal Krishna,Sahoo, Binayani
, p. 1307 - 1310 (2020/06/27)
A rapid and efficient microwave-mediated Green synthesis of oxadiazole derivatives (2a-e) is described based on reaction between benzohydrazide and various substituted benzoic acids. The use of microwave irradiation to carry out chemical reactions provide
Use of ester formylhydrazones for the synthesis of 1,2,4-triazole and 1,3,4-oxadiazole derivatives
Yildirim, Nuri,Bekircan, Olcay
, p. 160 - 163 (2013/07/05)
A series of ester formylhydrazones were synthesised by the reaction of alkyl imidate hydrochlorides with ormylhydrazine. Treatment of the ester formylhydrazones with acetic acid hydrazide, isonicotinic acid hydrazide, nicotinicacid hydrazide, and 4-hydroxybenzhydrazide resulted in the formation of either 4-acylamino-4H-1,2,4-triazoles or 2,5-disubstituted 1,3,4-oxadiazoles. 3-Alkyl-4-amino-4,5-dihydro-1H-1,2,4-triazol-5-ones were synthesised by the reaction of the ester formylhydrazones with carbohydrazide. Some arylidenamino compounds were synthesized by the reaction of 4-amino-4,5-dihydro-1H-1,2,4- triazol-5-ones with several aldehydes. These compounds were characterised by elemental analyses, IR, 1H NMR, and UV spectral techniques.
Electrosynthesis and screening of novel 1,3,4-oxadiazoles as potent and selective antifungal agents
Singh, Sushma,Sharma, Laxmi Kant,Saraswat, Apoorv,Siddiqui, Ibadur R.,Kehri, Harbans K.,Singh, Rana K. Pal
, p. 4237 - 4245 (2013/05/08)
The electrochemical oxidation of aldehyde-N-aroylhydrazone has been studied in the presence of NaClO4 as supporting electrolyte in MeOH solution using cyclic voltammetry and controlled potential electrolysis. The results indicate that intramolecular cyclization of aldehyde-N-aroylhydrazone has been successfully performed at a platinum electrode in an undivided cell with good yields of the corresponding 1,3,4-oxadiazoles at ambient conditions. The reaction products were characterized by spectroscopic methods and a mechanism was deduced from voltammetry studies. The antifungal activity of the synthesized compounds was evaluated on Fusarium oxysporum, Alternaria solani, Candida albicans and Aspergillus niger. The results revealed that all the synthesized compounds have significant antifungal activity against the tested fungi. Among the synthesized derivatives 7b, 7d, 7g, 7h, 7i, 7j and 7r were found to be the most effective antifungal compounds. The Royal Society of Chemistry 2013.
2,4,6-Tris[(4-dichloroiodo)phenoxy)]-1,3,5-triazine as a new recyclable hypervalent iodine(III) reagent for chlorination and oxidation reactions
Thorat, Prerana B.,Bhong, Bhagyashree Y.,Karade, Nandkishor Y.
supporting information, p. 2061 - 2066 (2013/10/21)
The synthesis of 2,4,6-tris[(4-dichloroiodo)phenoxy)]-1,3,5-triazine, as a new recyclable nonpolymeric analogue of (dichloroiodo)benzene, is achieved in two steps using 2,4,6-trichloro-1,3,5-triazine and 4-iodophenol. The application of 2,4,6-tris[(4-dichloroiodo)phenoxy)]-1,3,5-triazine for the chlorination reaction of various activated arenes, olefin, and 1,3-diketone is demonstrated. The reagent 2,4,6-tris[(4-dichloroiodo)phenoxy)]-1,3,5-triazine can be applied also for the oxidative synthesis of 1,3,4-oxadiazoles and 1,2,4-thiadiazoles under mild conditions in excellent yields. The recyclability of the 2,4,6-tris[(4-dichloroiodo)phenoxy)]-1,3,5-triazine was possible owing to the facile recovery and reuse of the coproduced 2,4,6-tris(4-iodophenoxy)-1,3,5- triazine from the reaction mixture due to its practical insolubility in methanol. Georg Thieme Verlag Stuttgart, New York.
The spectrophotometric study of a fluorescence-enhanced inclusion complex Threaded with β-cyclodextrin: Synthesis and characterization
Chiu, Yi-Hong,Liu, Jui-Hsiang
experimental part, p. 3368 - 3374 (2011/04/26)
A novel achiral monomer end-capped with a phenyl-[1,3,4]oxadiazolyl group and threaded through β-cyclodextrin was synthesized to investigate the host-guest interactions in the inclusion complex. 1H NMR studies revealed that one or two eyclodextrin molecules were threaded onto the synthesized achiral monomer, leading to the formation of a fibrous construction of self-assembled inclusion complexes. The formation of a self-assembled inclusion complex was identified using SEM and TEM. The highly ordered alignment of selfassembled supramolecules was confirmed using polarized optical microscopy. We demonstrate an easy process for the fabrication of nano-structured self-assembled inclusion complexes in pyridine/ethanol (1 mL/10 mL) as well as the enhancement of photo-induced fluorescence via monomers end-capped with a phenyl-[1,3,4]oxadiazolyl moiety threaded with β-cyclodextrins.
A multicomponent rhenium-based triplet emitter for organic electroluminescence
Liu,Li,Li,Hong,Zhao,Liu,Li
, p. 54 - 58 (2008/02/13)
A novel Re complex functionalized by a hole-transport and an electron-transport groups was utilized to fabricate organic light-emitting devices (OLEDs). A current efficiency up to 8.2 cd A-1 corresponding to a power efficiency of 4.6 ml W-1 and a peak brightness as high as 5500 cd m-2 were obtained. These results represent the best values reported for OLEDs based on rhenium complexes. Short lifetime, enhanced carrier injection capability of Re complex, and efficient charge-trapping followed by exciton confinement in the emissive layer should be responsible for the outstanding electrophosphorescent performances.
A comparison of crystalline- and graft polymer-based chemosensors
Broadwater, Steven J.,Hickey, Mary Kay,McQuade, D. Tyler
, p. 11154 - 11155 (2007/10/03)
Herein, we report a highly sensitive luminescent thin film chemosensor constructed out of a small-molecule donor/acceptor system. Two types of films were compared: one using a small-molecule crystalline donor/acceptor pair and the other using a donor-graf
Soluble electroluminescent poly(phenylene vinylene)s with balanced electron- and hole injections
Lee,Chen,Chen,Wei,Fann
, p. 2296 - 2307 (2007/10/03)
We report a new route for the design of efficient soluble electroluminescent PPV-based copolymers bearing electron-deficient oxadiazole (OXD) moieties on side chains. The introduction of OXD through a long alkylene spacer with PPV backbone provides a molecular dispersion of OXD in the film; both the side chain OXD and the main chain PPV do retain their own electron-transport and emissive properties, respectively. The use of phenylene vinylene derivatives with asymmetric and branched substituents and a long spacer provides solubility for ease of device fabrication as well as amorphous structure to allow a well-mixing of OXD groups with the main chains. By properly adjusting the OXD content through copolymerization, we can tailor the chemical structure of electroluminescent material to give a balance of hole- and electron injections for various metal cathodes, such that the quantum efficiency is significantly improved and the turn-on voltage is reduced for the devices with aluminum and calcium. For the device with calcium fabricated in open air, a maximum brightness of 15000 cd/m2 at 15 V/100 nm and a maximum luminance efficiency of 2.27 cd/A can be obtained, respectively, about 30 times brighter and 9.4 times more efficient than those with the corresponding homopolymer, poly[2-methoxy-5-(2′-ethylhexyloxy)-p-phenylenevinylene] (MEH-PPV). The use of physical blends to simulate the copolymers provides no significant improvement, since phase-separation structures appear, causing an inefficient utilization of OXD and sometimes voltage-dependent emission spectra. The present route permits a fabrication of single layer PLED with high brightness, high efficiency, and low turn-on voltage.
The Hydroxy Derivatives of 2,5-Diphenyl-1,3,4-oxadiazole
Jacobsen, Noel W.,Philippides, Athena E.
, p. 1911 - 1914 (2007/10/02)
An unambiguous synthesis for each of the monohydroxy derivatives of 2,5-diphenyl-1,3,4-oxadiazole is reported.
