244-99-5

Usage

Uses

Used in Organic Chemistry:
5H-Indeno[1,2-b]pyridine is used as a building block for synthesizing new chemical products. Its fused ring structure allows for the creation of complex molecules that can be utilized in various applications within the field of organic chemistry.
Used in Pharmaceutical Drug Development:
5H-Indeno[1,2-b]pyridine is used as a key component in the development of pharmaceutical drugs. Its unique structure and properties make it a valuable asset in the design and synthesis of new medications, potentially leading to the discovery of novel therapeutic agents.
Used in the Chemical Industry:
5H-Indeno[1,2-b]pyridine is used as a raw material in the production of various chemical products. Its versatility and the ability to form complex molecules make it a valuable resource in the manufacturing of a wide range of chemical compounds.
Used in Research and Development:
5H-Indeno[1,2-b]pyridine is used as a research compound in the exploration of new chemical reactions and processes. Its unique properties and potential applications make it an interesting subject for scientific investigation, potentially leading to new discoveries and advancements in the field of chemistry.

InChI:InChI=1/C12H9N/c1-2-6-11-9(4-1)8-10-5-3-7-13-12(10)11/h1-7H,8H2

Upstream product

• 3882-46-0 5H-indeno[1,2-b]pyridin-5-one 
• 10273-89-9 2-(2-methylphenyl)pyridine 
• 33421-20-4 2-(2-methylphenyl)pyridine N-oxide 
• 72568-66-2 9-Bromo-4-azafluorene 
• 72568-67-3 4-aza-9-fluorenylhydrazone 
• 33421-39-5 2-phenyl-3-pyridinecarboxylic acid 
• 230-27-3 7,8-benzoquinoline 
• 98-80-6 phenylboronic acid 
• 57214-73-0 o-methoxybenzimidic acid ethyl ester 
• 107-02-8 acrolein 
• 825-60-5 benzimidic acid ethyl ester 
• 107-18-6 allyl alcohol 
• 591-51-5 phenyllithium 
• 2369-18-8 2-fluoro-3-methylpyridine 

Downstream Products

• 3882-46-0 5H-indeno[1,2-b]pyridin-5-one 
• 135265-18-8 9-(α-hydroxybenzylidene)-4-azafluorene 
• 84443-30-1 9,9-Dichloro-4-azafluorene 
• 86445-17-2 E-3'-(p-nitrophenyl)spiro<4-azafluorene-9,2'-oxirane> 
• 85658-50-0 4'-Hydroxy-2',6'-diphenyl-3'-carbethoxyspiro(4-azafluorene-9,1'-cyclohex-3'-ene) 
• 84443-28-7 (E)-3'-phenylspiro<4-azafluorene-9,2-ozirane> 
• 71483-76-6 bis(4-azafluorenylidene) 
• 135265-19-9 (Z)-9-phenylaminomethylene-4-azafluorene 
• 135265-20-2 (E)-9-phenylaminomethylene-4-azafluorene 
• 874466-03-2 5-(2-bromobenzyl)-5-methyl-5H-indeno[1,2-b]pyridine 
• 118453-30-8 C₂₈H₂₂N₂O₂ 
• 10445-91-7 4-(Chloromethyl)pyridine 
• 89971-97-1 β-ethyl N-p-tolylcarbamate 
• 89995-25-5 9--4-azafluorene 

Relevant academic research and scientific papers

Sequential C-H and C-C Bond Cleavage: Divergent Constructions of Fused N-Heterocycles via Tunable Cascade

Streamlining the generation of diverse highly functionalized molecules from abundant feedstocks holds great synthetic promises and challenges in pharmaceutical and material discovery. Herein, we report a tunable selectivity in multiple cascade reactions for the divergent assembly of fused N-heterocycles, comprising sequential activation of C-H and C-C bonds. Isolatable indene-type intermediates might be responsible for the generation of densely substituted fused pyridines, azepines, and azafluorenones products. The tolerance of strongly coordinating N-heterocycles, and those readily applicable for the late-stage modifications of pharmaceuticals and material molecules precursors, further demonstrated the synthetic robustness of this transformation.

Preparation method of pyridino-indene compound

The invention relates to the technical field of organic synthesis, in particular to a preparation method of a pyridino-indene compound. According to the preparation method of the pyridino-indene compound provided by the invention, a compound shown as a formula II or a compound shown as a formula II' reacts with a compound shown as a formula III so as to obtain a compound shown as a formula I. According to the preparation method of the pyridino-indene compound provided by the invention, novel combination of a substrate and coupling can be designed, and the preparation of the pyridino-indene compound is realized through a cascade reaction.

Scope of regioselective Suzuki reactions in the synthesis of arylpyridines and benzylpyridines and subsequent intramolecular cyclizations to azafluorenes and azafluorenones

The current investigation on regioselective Suzuki reactions of 2,3-dihalopyridines and 2-halo-3-halomethylpyridines yielded the unexplored synthesis of arylpyridines and benzylpyridines bearing synthetic handles for further functionalization. Indeed, the scope of intramolecular cyclizations of arylpyridines and benzylpyridines prepared in this study for the synthesis of azafluorenes and azafluorenones has been investigated.

INDENOTRIPHENYLENE DERIVATIVES AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME

The present invention discloses a new indenotriphenylene derivatives and organic light emitting device using the derivatives. The organic light emitting device employing new indenotriphenylene derivatives as host material can lower driving voltage, prolong half-lifetime, increasing efficiency. The new indenotriphenylene derivatives are represented by the following formula (A): Wherein A1, A2 are substituted or unsubstituted fused ring hydrocarbon units with one to five rings. Preferably A1, A2 are phenyl group, naphthyl group, anthracenyl group, pyrenyl group, chrysenyl group. Perylenyl group. R1 to R4 are identical or different. R1 to R4 are independently selected from the group consisting of a hydrogen atom, a halide, alkyl group having 1 to 20 carbon atoms, a substituted or unsubstituted aryl group having 6 to 30 carbon atoms, a substituted or unsubstituted aralkyl group having 6 to 30 carbon atoms, a substituted or unsubstituted heteroaryl group having 6 to 30 carbon atoms. X is selected from carbon atom or nitrogen atom.

FLUORENE COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME

The present invention discloses a new fluorene compound and organic EL device using the compound. The organic EL device employing the new fluorene compound as host material can lower driving voltage, prolong half-lifetime. The fluorene compound can functions as blue emitting host material of a light emitting layer and improve CIE colour purity in blue emitting device. The fluorene compound are represented by the following formula(A): Wherein R1 to R6 are identical or different. R1 to R6 are independently selected from the group consisting of a hydrogen atom, a halide, alkyl group having 1 to 20 carbon atoms, a substituted or unsubstituted aryl group having 6 to 30 carbon atoms, a substituted or unsubstituted aralkyl group having 6 to 30 carbon atoms, a substituted or unsubstituted heteroaryl group having 6 to 30 carbon atoms. R7?R13 are identical or different R7 to R13 are independently selected from the group consisting of hydrogen atom, halide, alkyl group, aryl group, heteroaryl group. m and n are independently an integer of 0 to 3, X is selected from carbon or nitrogen.

AZAFLUORENE DERIVATIVE AND ORGANIC LIGHT-EMITTING DEVICE USING THE DERIVATIVE

A novel azafluorene derivative and an organic light-emitting device having the derivative are provided. The organic light-emitting device includes a pair of electrodes composed of an anode and a cathode one of which is a transparent or semi-transparent electrode, and an organic compound layer interposed between the pair of electrodes. The organic compound layer contains the azafluorene derivative represented by the following general formula (I):

Identification of a novel antifungal agent based on a pharmacophoric group in cryptolepine

Though its mechanism of action is not yet known, cryptolepine (1) possesses desirable properties to serve as a lead in developing novel antifungal agents. Several analogues of cryptolepine were synthesized in order to identify the pharmacophoric groups present in the molecule. Rational modification of the structure of cryptolepine has resulted in several analogues fifty to a hundred fold more potent than cryptolepine.

α,α-disubstituted aromatics and heteroaromatics as cognition enhancers

Cognitive defeciencies or neurological dysfunction in mammals are treated with α,α-disubstituted aromatic or heteroaromatic compounds. The compounds have the formula: STR1 or a salt thereof wherein X and Y are taken together to form a saturated or unsaturated carbocyclic or heterocyclic first ring and the shown carbon in said ring is α to at least one additional aromatic ring or heteroaromatic ring fused to the first ring; one of Het1 is 2, 3 or 4-pyridyl or 2, 4, or 5-pyrimidinyl and the other is selected from (a) 2, 3, or 4-pyridyl, (b) 2, 4, or 5-pyrimidinyl, (c) 2-pyrazinyl, (d) 3, or 4-pyridazinyl, (e) 3, or 4-pyrazolyl, (f) 2, or 3-tetrahydrofuranyl, and (g) 3-thienyl.

Spiro-tricyclicaromatic succinimide derivatives

Disclosed are substituted or unsubstituted planar tricyclic fluorene or nuclear analogs thereof, spiro-coupled to a five-membered ring containing a secondary amide, and the pharmaceutically acceptable salts thereof. These compounds are useful, inter alia in the treatment of diabetes. Also disclosed are processes for the preparation of such compounds; pharmaceutical compositions comprising such compounds; and methods of treatment comprising administering such compounds and compositions when indicated for, inter alia, long term, prophylactic treatment of the diabetes syndrome. A particularly preferred class of compounds comprise difluoro-dialkoxy substituted spiro-(9H-fluorene-9,4'-imidazolidine)-2,40 ,5-diones.

REACTION OF 9-HYDROXY(CHLORO, BROMO)-4-AZAFLUORENE TO BIS

4-Aza-fluoren-9-ol and 9-chloro(bromo)-4-azafluorenes are converted in high yields upon refluxing with thionyl chloride to form bis.At about 20 deg C, azafluorenol and thionyl chloride form 9-chloro-4-azafluorene.Mechanisms are proposed for these reactions.