24431-17-2

Basic information

• Product Name: Benzenemethanamine, N-[[4-(dimethylamino)phenyl]methylene]-
• CAS NO: 24431-17-2
• Molecular Formula: C16H18N2
• Molecular Weight: 238.332
• Mol File: 24431-17-2.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: Benzenemethanamine, N-[[4-(dimethylamino)phenyl]methylene]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanamine, N-[[4-(dimethylamino)phenyl]methylene]-(24431-17-2)
• EPA Substance Registry System: Benzenemethanamine, N-[[4-(dimethylamino)phenyl]methylene]-(24431-17-2)

Safety Data

• Hazardous Substances Data: 24431-17-2(Hazardous Substances Data)

Upstream product

• 31401-61-3 N‐(4‐(dimethylamino)benzylidene)benzylamine 
• 141-52-6 sodium ethanolate 
• 1753-47-5 5-(4-dimethylaminobenzylidene)barbituric acid 
• 130517-96-3 N-[(1E)-(4-chlorophenyl)methylidene]benzenemethanamine 
• 130517-94-1 (E)-N-benzyl-1-(4-methoxyphenyl)methanimine 
• 49546-71-6 5-(4-methoxybenzylidene)barbituric acid 
• 27402-31-9 5-(4-chlorobenzylidene)barbituric acid 
• 131196-45-7 N-[(1E)-thiophen-2-ylmethylidene]benzenemethanamine 
• 100-10-7 4-dimethylamino-benzaldehyde 
• 100-46-9 benzylamine 
• 123-11-5 4-methoxy-benzaldehyde 
• 104-88-1 4-chlorobenzaldehyde 
• 2826-28-0 p-(N-dimethylamino benzylidene) malononitrile 
• 100-47-0 benzonitrile 

Downstream Products

• 31401-61-3 N‐(4‐(dimethylamino)benzylidene)benzylamine 
• 55096-85-0 4-((benzylamino)methyl)-N,N-dimethylaniline 
• 27046-22-6 3-benzyl-2-(4-dimethylamino-phenyl)-6-phenyl-2,3-dihydro-[1,3,5]oxadiazin-4-one 
• 3476-94-6 9-(p-dimethylaminophenyl)-3,3,6,6-tetramethyl-1,2,3,4,5,6,7,8,9,10-decahydroacridine-1,8-dione 

Relevant articles and documents

Compound, preparation method thereof and application of compound as fluorescent probe

The invention discloses a compound, a preparation method thereof and application of the compound as a fluorescent probe, wherein the compound I is selected from at least one compound of the chemical formula shown I. I In formula R1 . R2 Independently selected C1 - C5 Alkyl, C1 - C5 Alkoxy and substituted C1 - C5 At least one of the alkyl I of the alkyl group. R3 Be selected from C1 - C5 Alkyl groups. Substituted C1 - C5 At least one of the alkyl II groups of the alkyl group. The fluorescence probe provided by the invention can detect the morphology and the position of protein aggregation states through fluorescent imaging in living cells.

Preparation of homoallylic amines via a three-component coupling process

A three-component synthesis of homoallylic amines is described. The allylboronic species were generated in situ by homologation of vinyl boroxines with trimethylsilyldiazomethane, then followed by trapping of the allylboron intermediate with imines. Twenty-seven compounds were successfully prepared in moderate to high yields. Imines bearing various functional groups were tolerated, including aliphatic, aromatic and heteroaromatic substituents. Further elaboration of some of the homoallylic amines to form azeditines is also reported.

Organocatalyzed and uncatalyzed C=C/C=C and C=C/C=N exchange processes between knoevenagel and imine compounds in dynamic covalent chemistry

Molecular diversity generation through reversible component exchange has acquired great importance in the last decade with the development of dynamic covalent chemistry. We explore here the recombination of components linked by C=C and C=N bonds through reversible double-bond formation, and cleavage in C=C/C=C and C=C/C=N exchange processes. The reversibility of the Knoevenagel reaction has been explored, and C=C/C=C C/C exchanges have been achieved among different benzylidenes, under organocatalysis by secondary amines such as L-proline. The substituents of these benzylidenes were shown to play a very important role in the kinetics of the exchange reactions. L-Proline is also used to catalyze the reversible C=C/C=C exchange between Knoevenagel derivatives of barbituric acid and malononitrile. Finally, the interconversion between Knoevenagel derivatives of dimethylbarbituric acid and imines (C=C/C=N exchange) has been studied and was found to occur rapidly in the absence of catalyst. The results of this study pave the way for the extension of dynamic combinatorial chemistry based on C=C/C=C and C=C/C=N exchange systems.