25436-07-1

Usage

Uses

Used in Organic Chemistry:
TMS-CA is used as a silylating agent for the conversion of certain organic compounds into derivative forms that are more amenable to analysis or further reactions. This application is crucial in various research and development processes within the field of organic chemistry.
Used in Characterization Techniques:
TMS-CA is employed in diverse forms of characterization techniques, such as Nuclear Magnetic Resonance (NMR), to facilitate the analysis of organic compounds. Its use in these techniques helps researchers gain a better understanding of the structure and properties of the compounds being studied.
Used in Research and Development:
In the context of research and development, TMS-CA is used as a reagent to aid in the synthesis and modification of organic compounds. Its versatility in facilitating reactions and transformations makes it a valuable tool for scientists working on the development of new compounds and materials.

InChI:InChI=1/C5H9Cl3O2Si/c1-11(2,3)10-4(9)5(6,7)8/h1-3H3

Upstream product

• 43112-38-5 3-(trimethylsilyl)-2-oxazolidinone 
• 76-03-9 trichloroacetic acid 
• 107-46-0 Hexamethyldisiloxane 
• 16029-98-4 trimethylsilyl iodide 
• 1825-62-3 ethyl trimethylsilyl ether 
• 4124-31-6 trichloroacetic acid anhydride 
• 762-72-1 allyl-trimethyl-silane 
• 75-77-4 chloro-trimethyl-silane 
• 650-51-1 sodium trichloroacetate 
• 999-97-3 1,1,1,3,3,3-hexamethyl-disilazane 

Downstream Products

• 18156-74-6 1-(Trimethylsilyl)imidazole 
• 43112-38-5 3-(trimethylsilyl)-2-oxazolidinone 
• 3553-94-4 1-trimethylsilanyl-azepan-2-one 
• 85695-31-4 Trimethyl-(1-trichloromethyl-cyclohex-2-enyloxy)-silane 
• 98188-40-0 Trimethyl-(3-trichloromethyl-cyclohex-1-enyloxy)-silane 
• 1014-66-0 trimethyl(4-nitrophenoxy)silane 
• 17878-44-3 (4-bromophenoxy)trimethylsilane 
• 27607-77-8 trimethylsilyl trifluoromethanesulfonate 
• 25237-79-0 (4-tert-butylphenoxy)trimethylsilane 
• 85695-25-6 Trimethyl-[2,2,2-trichloro-1-(3,5-dichloro-phenyl)-ethoxy]-silane 
• 137787-28-1 (S)-2,2-Dimethyl-4-((R)-2,2,2-trichloro-1-hydroxy-ethyl)-oxazolidine-3-carboxylic acid benzyl ester 
• 137787-29-2 (R)-2,2-Dimethyl-4-((S)-2,2,2-trichloro-1-hydroxy-ethyl)-oxazolidine-3-carboxylic acid benzyl ester 
• 84678-74-0 trimethyl(4-cyanonphenoxy)silane 
• 85695-26-7 [2,2,2-trichloro-1-(4-trimethylsiloxyphenyl)ethoxy]trimethylsilane 

Relevant academic research and scientific papers

Trimethylsilyl Esters as Novel Dual-Purpose Protecting Reagents

Trimethylsilyl esters, AcOTMS, BzOTMS, TCAOTMS, etc., are inexpensive and chemically stable reagents that pose a negligible environmental hazard. Such compounds prove to serve as efficient dualpurpose reagents to respectively achieve acylation and trimethylsilylation of alcohols under acidic or basic conditions. Herein, a detailed study on protection of various substrates and new methodological investigations is described.

Method for Producing Acyloxysilanes, Acyloxysilanes Obtained Thereby, and Use of Same

An object of the invention is to provide a method for efficiently producing an acyloxysilane which is useful as a functional chemical, an acyloxysilane obtained thereby, and the use thereof. The present invention provides: a method for producing an acyloxysilane, including a reaction step of reacting an alkoxysilane with a carboxylic anhydride in the presence of a catalyst, wherein the alkoxysilane is a specified alkoxysilane represented by General Formula (I), the carboxylic anhydride is a specified carboxylic acid represented by General Formula (IIA) or (IIB), the catalyst is an acid catalyst, and an acyloxysilane obtained in the reaction step is a specified acyloxysilane represented by General Formula (IIIA) or (IIIB); and the use of the acyloxysilane as a surface treatment agent or the like.

B(C6F5)3-catalyzed allylation of propargyl acetates with allylsilanes.

[reaction: see text] An efficient method for the B(C(6)F(5))(3)-catalyzed allylation of secondary propargylic alcohol derivatives with allylsilanes has been developed. This method allows for the facile synthesis of a variety of 1,5-enynes in good to high yields with a number of functionalities, such as nitro, chloro, ester, and boronic ester, being tolerated under the reaction conditions.

NOVEL TRICHLOROACETYL BASED SILYLATIONS: SIMPLE METHODS FOR t-BUTYLDIMETHYLSILYLATIONS AND FOR THE PROTECTION OF AMINO GROUPS.

A new reagent for t-butyldimethylsilylation has been developed and the known trimethylsilyl trichloroacetate (1) has been shown to be of use for N-silylating amines.

Reagents and synthetic methods. 31. Silylations with N-trimethylsilyl-2-oxazolidinone (TMSO)

Silylation of ketones, alcohols, mercaptans, and carboxylic acids with N-trimethylsilyl-2-oxazolidinone (TMSO) and triflic acid as catalyst has been described from synthetic and mechanistic points of view.

A FACILE SILYLATION OF CARBOXYLIC ACIDS WITH HEXAMETHYLDISILOXANE

It was found that, in the presence of a catalytic amount of sulfuric acid, hexamethyldisiloxane silylates carboxylic acids to give trimethylsilyl carboxylates in good yields.