25775-89-7

Basic information

• Product Name: N,3-DIPHENYLACRYLAMIDE
• Synonyms: N,3-DIPHENYLACRYLAMIDE;AURORA KA-3355;(2E)-N,3-DIPHENYLACRYLAMIDE;N-PHENYLCINNAMAMIDE;N,3-diphenylacrylamide (en);2-PropenaMide, 3-phenyl-N-phenyl-, (2E)-
• CAS NO: 25775-89-7
• Molecular Formula: C₁₅H₁₃NO
• Molecular Weight: 223.27
• Mol File: 25775-89-7.mol
• Article Data: 62

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N,3-DIPHENYLACRYLAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N,3-DIPHENYLACRYLAMIDE(25775-89-7)
• EPA Substance Registry System: N,3-DIPHENYLACRYLAMIDE(25775-89-7)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 25775-89-7(Hazardous Substances Data)

Usage

General Description

N,3-Diphenylacrylamide is a chemical compound with the molecular formula C15H13NO. It is a white crystalline powder that is insoluble in water but soluble in organic solvents. N,3-DIPHENYLACRYLAMIDE is commonly used as a monomer in the production of polymers and copolymers, particularly in the synthesis of cross-linked gels and hydrogels. It also has applications in the field of organic synthesis, as well as in the pharmaceutical and cosmetic industries. N,3-Diphenylacrylamide is known for its ability to form stable and durable polymer networks, making it a valuable component in various materials and products.

Upstream product

• 62-53-3 aniline 
• 621-82-9 Cinnamic acid 
• 104-55-2 3-phenyl-propenal 
• 103-84-4 Acetanilid 
• 4360-47-8 cinnamonitrile 
• 114-83-0 1-acetyl-2-phenylhydrazine 
• 15093-36-4 1-isopropyl-3-phenylthiourea 
• 27829-46-5 N,N-diethylcinnamide 
• 66680-87-3 (2-phenylvinyl)tributylstannane 
• 103-71-9 phenyl isocyanate 
• 103-36-6 ethyl 3-phenyl-2-propenoate 
• 84958-06-5 C₂₂H₁₉NO₃S 
• 29834-36-4 trans-3-bromo-1,4-diphenylazetidin-2-one 
• 100-42-5 styrene 

Downstream Products

• 14371-10-9 (E)-3-phenylpropenal 
• 3271-81-6 hydrocinnamanilide 
• 93500-91-5 α,β-dibromohydrocinnamanilide 
• 1020478-99-2 N-phenyl-cinnamimidoyl chloride 
• 1681-94-3 4-dimethylaminochalcone 
• 34188-23-3 α-Methylthio-β-chlordihydrozimtsaeureanilid 
• 34193-80-1 3-Chloro-2-(2-chloro-ethylsulfanyl)-3,N-diphenyl-propionamide 
• 104-55-2 3-phenyl-propenal 
• 1139588-27-4 N,5-diphenyl-4,5-dihydroisoxazol-3-amine 
• 16619-19-5 N-morpholinocinnamide 
• 4888-33-9 4-phenyl-3,4-dihydro-1H-quinolin-2-one 
• 51527-49-2 3-(4-methoxyphenyl)-3-phenylpropanoic acid N-phenylamide 

Relevant articles and documents

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Umpolung cyclization reaction of: N -cinnamoylthioureas in the presence of DBU

A novel regioselective cyclization reaction of N-cinnamoylthioureas leading to six- or five-membered heterocyclic compounds was developed. N-Cinnamoylthioureas in the presence of trifluoroacetic acid (TFA) underwent the well-established intramolecular cycloaddition reaction to give 2-imino-2,3,5,6-tetrahydro-4H-1,3-thiazin-4-ones in good yields. On the other hand, the reaction with 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) proceeded in an unprecedented umpolung cyclization fashion to afford five-membered 2-imino-1,3-thiazolidin-4-ones and/or 2-thioxoimidazolidine-4-ones. The reaction was considered to occur via a cycloadduct of DBU with the cinnamoyl moiety followed by intramolecular attack of the thiourea group.

Iron-catalyzed oxidative amidation of acylhydrazines with amines

A new approach for amide bond formation via a mild and efficient Iron-catalyzed cross-coupling reaction of acylhydrazines and amines using TBHP as oxidant is described. This protocol is compatible with a wide range of amines and acylhydrazines. In addition, the synthetic application of the reaction is presented.

Chlorination Reaction of Aromatic Compounds and Unsaturated Carbon-Carbon Bonds with Chlorine on Demand

Chlorination with chlorine is straightforward, highly reactive, and versatile, but it has significant limitations. In this Letter, we introduce a protocol that could combine the efficiency of electrochemical transformation and the high reactivity of chlorine. By utilizing Cl3CCN as the chloride source, donating up to all three chloride atom, the reaction could generate and consume the chlorine in situ on demand to achieve the chlorination of aromatic compounds and electrodeficient alkenes.