25983-76-0

Usage

Uses

Used in Fragrance Industry:
2,2-Dimethyl-6-acetyl-7-methoxy-2H-1-benzopyran-5-ol is used as a fragrance ingredient in perfumes and other scented products for its sweet and vanilla-like scent, adding a warm and comforting aroma to personal care and household products.
Used in Medicinal Applications:
2,2-Dimethyl-6-acetyl-7-methoxy-2H-1-benzopyran-5-ol is used as a potential medicinal compound for its suggested antioxidant and anti-inflammatory effects, although further studies are needed to fully understand its health benefits and establish its efficacy in various therapeutic applications.

Upstream product

• 31525-67-4 dimethylacetal of 3-methyl-3-hydroxybutyraldehyde 
• 3602-54-8 4,6-dihydroxy-2-methoxyacetophenone 
• 32550-59-7 6-Acetyl-5-hydroxy-7-methoxy-3,4-dihydro-2,2-dimethyl-2H<1>benzopyran 
• 30403-01-1 1-[2,4-dihydroxy-6-methoxy-3-(3-methylbut-2-enyl)phenyl]ethanone 
• 107-86-8 3,3-dimethyl acrylaldehyde 
• 1019-60-9 2,3-dihydro-5-hydroxy-7-methoxy-2,2-dimethyl-4H-1-benzopyran-4-one 
• 75-36-5 acetyl chloride 
• 68097-14-3 4-acetyl-5-hydroxy-1,3-phenylene bis(4-methylbenzenesulfonate) 
• 404597-94-0 1-(2-methoxy-4,6-bis(methoxymethoxy)phenyl)ethan-1-one 
• 480-66-0 2,4,6-trihydroxyacetophenone 
• 2174-64-3 5-methoxyresorcinol 
• 78-79-5 isoprene 
• 74047-32-8 2,4-dihydroxy-3-iodo-6-methoxyphenyl methyl ketone 
• 450336-13-7 1-(2,6-dihydroxy-4-(methoxymethoxy)-3-(3-methylbut-2-en-1-yl)phenyl)ethanone 

Downstream Products

• 128031-07-2 1,3-dioxo-1-(5-hydroxy-7-methoxy-2,2-dimethyl-2H-1-benzopyran-6-yl)-3-(2',4'-dimethoxy-phenyl)-propane 
• 119309-05-6 6-O-acetyl-2,2-dimethyl-5-(4'-methoxy-benzoyloxy)-2H-benzopyran 
• 35930-31-5 Alloptaeroxylin methyl ether 
• 143885-76-1 3-(3,4-dimethoxyphenyl)-1-(5-hydroxy-7-methoxy-2,2-dimethyl-2H-chromen-6-yl)propenone 
• 41724-53-2 2-hydroxy-6'-methoxy-6'',6''-dimethylchromeno(4',3':2'',3'')chalcone 
• 76265-10-6 rac-4β-Hydroxyobovatachromen 
• 92413-38-2 1-(3,4-Dihydro-5-hydroxy-7-methoxy-2,2-dimethyl-2H-1-benzopyran-6-yl)-3-<(tetrahydro-2H-pyran-2-yl)oxyphenyl>-2-propen-1-on 
• 92413-39-3 9,10-Dihydro-5-methoxy-8,8-dimethyl-2-<(tetrahydro-2H-pyran-2-yl)oxyphenyl>-2H,8H-benzo<1,2-b:4-b'>dipyran 
• 92413-40-6 (2R,3S,4S)-5-Methoxy-8,8-dimethyl-2-[4-(tetrahydro-pyran-2-yloxy)-phenyl]-3,4,9,10-tetrahydro-2H,8H-pyrano[2,3-f]chromene-3,4-diol 
• 92413-40-6 (2S,3S,4S)-5-Methoxy-8,8-dimethyl-2-[4-(tetrahydro-pyran-2-yloxy)-phenyl]-3,4,9,10-tetrahydro-2H,8H-pyrano[2,3-f]chromene-3,4-diol 
• 92413-41-7 Acetic acid (2R,3R,4S)-3-acetoxy-5-methoxy-8,8-dimethyl-2-[4-(tetrahydro-pyran-2-yloxy)-phenyl]-3,4,9,10-tetrahydro-2H,8H-pyrano[2,3-f]chromen-4-yl ester 
• 92413-41-7 Acetic acid (2S,3R,4S)-3-acetoxy-5-methoxy-8,8-dimethyl-2-[4-(tetrahydro-pyran-2-yloxy)-phenyl]-3,4,9,10-tetrahydro-2H,8H-pyrano[2,3-f]chromen-4-yl ester 
• 1000618-51-8 1-(5-hydroxy-7-methoxy-2,2-dimethyl-2H-chromen-6-yl)-3-[4-(methoxymethoxy)phenyl]-2-propen-1-one 
• 1393809-19-2 (+/-)-3-(3,5-dimethoxyphenyl)-3-hydroxy-1-(5-hydroxy-7-methoxy-2,2-dimethyl-2H-chromen-6-yl)propan-1-one 

Relevant academic research and scientific papers

Total synthesis of isorobustin

The synthesis of isorobustin 1 in four steps from 5-methoxyresorcinol proceeds in an overall yield of 34%. The key step involves the arylation of a 4-hydroxy-2H-l-benzopyran-2-one 6 by 3,4-methylenedioxyphenyllead triacetate 9 in a chemoselective and regioselective manner.

Neuroregenerative Potential of Prenyl- And Pyranochalcones: A Structure-Activity Study

Loss of neuronal tissue is a hallmark of age-related neurodegenerative diseases. Since adult neurogenesis has been confirmed in the human brain, great interest has arisen in substances stimulating the endogenous neuronal regeneration mechanism based on ad

Chromane-like cyclic prenylflavonoids for the medical intervention in neurological disorders

The present invention relates to certain chromane-like cyclic prenylflavonoids, in particular the compounds of formulae (I), (II) and (III) as described and defined herein, for use in the treatment or prevention of a neurological disorder, as well as their use in promoting neuronal differentiation, neurite outgrowth and neuroprotection.

New synthetic approaches to naturally occurring and unnatural pyranoflavones

Total synthesis of biologically interesting natural and unnatural pyranoflavones has been accomplished starting from readily available 2,4-dihydroxyacetophenone or 2,4-dihydroxy-6-methoxyacetophenone in three steps, i.e., benzopyran formation, condensatio

Concise Synthetic Approaches to Naturally Occurring β- Hydroxypyranochalcones: First Total Synthesis of Purpurenone, Its Derivative, and Praecansone B

The total synthesis of biologically interesting β- hydroxypyranochalcones, purpurenone (1), its derivative 2, praecansone B (3), and pongapinone A (4) has been accomplished starting from commercially available 2,4-dihydroxyacetophenone or 6-methoxy-2,4-di

The synthesis of morusin as a potent antitumor agent

Morusin, which can be isolated from Chinese herbal medicine, is achieved in which the longest linear sequence is only 13 steps in 12% overall yield from commercially available phloroglucinol. In addition, the metal/EtSH reagents for regioselective demethy

Synthesis, cytotoxicity, and antioxidative activity of minor prenylated chalcones from Humulus lupulus

The minor hop (Humulus lupulus) chalcones 3′-geranylchalconaringenin (3), 5′-prenylxanthohuraol (4), flavokawin (5), xanthohumol H (8), xanthohumol C (9), and 1″,2″-dihydroxanthohumol C (10) were synthesized. The non-natural chalcones 3′-geranyl-6′-O- methylchalconaringenin (2), 3′-methylflavokawin (6), and 2′-0-methyl-3′-prenylchalconaringenin (7) were also synthesized. Cytotoxicity was investigated in HeLa cells, and these compounds all had IC 50 values comparable to xanthohumol (8.2-19.2 μM). The ORAC-fluorescein assay revealed potent antioxidative activity for 7 and 8 with 5.2 and 4.8 Trolox equivalents, respectively.

Total synthesis of (±)-glyflavanone by a rigid quaternary ammonium salt

Total synthesis of (±)-glyflavanones and glychalcones was accomplished starting from the known 1-(5-hydroxy-7-methoxy-2,2-dimethyl-2H- chromen-6-yl)ethanone (6). A new approach to synthesis of flavanones, based on a high yielding N-benzylcinchoninium salt

An efficient and rapid synthetic route to biologically interesting pyranochalcone natural products

An efficient and concise total synthesis of naturally occurring pyranochalcones was achieved from readily available 2,4-dihydroxyacetophenone and 2,4-dihydroxy-6-methoxyacetophenone. The key steps in the synthetic strategy were ethylenediamine diacetate-c

Concise total synthesis of biologically interesting pyranochalcone natural products: Citrunobin, boesenbergin A, boesenbergin B, xanthohumol C, and glabrachromene

New and efficient synthetic approaches to the biologically interesting natural products citrunobin, boesenbergins A and B, xanthohumol C, and glabrachromene are described. The key strategies involve ethylenediamine diacetate catalyzed benzopyran formation