26472-41-3

Usage

Uses

(R)-Humulone (CAS# 26471-41-3) can be used as a chemosensory receptor ligand.

Purification Methods

Crystallise humulon from Et2O. It dissolves slightly in hot H2O but precipitates on cooling. It has max () 237 (13,760) and 282 (8,330) in EtOH. [Wollmer Chem Ber 49 780 1916, Carson J Am Chem Soc 73 4652 1951, Beilstein 8 II 537, 8 III 4034, 8 IV 3410.]

InChI:InChI=1/C21H30O5/c1-12(2)7-8-15-18(23)17(16(22)11-14(5)6)20(25)21(26,19(15)24)10-9-13(3)4/h7,9,14,23-24,26H,8,10-11H2,1-6H3/t21-/m1/s1

Upstream product

• 4374-93-0 deoxyhumulone 
• 125137-35-1 (+/-)-humulone 

Downstream Products

• 78-78-4 methylbutane 
• 107152-23-8 3-methyl-1-(2,3,4,6-tetrahydroxy-5-isopentyl-phenyl)-butan-1-one 
• 504-85-8 4-methyl-pent-3-enoic acid 
• 78-84-2 isobutyraldehyde 
• 67-64-1 acetone 
• 56143-68-1 (3aS,5aR,8aR)-3a-Hydroxy-7-isopropenyl-6,6-dimethyl-2-(3-methyl-butyryl)-tetrahydro-cyclopenta[c]pentalene-1,3,4-trione 
• 81677-88-5 3,7-Dihydroxy-2,2-dimethyl-6-(3-methyl-butyryl)-7a-(4-methyl-pent-3-enoyl)-3,4,4a,7a-tetrahydro-2H-cyclopenta[b]pyran-5-one 
• 1534-03-8 trans-isohumulone 
• 467-72-1 trans-isohumulone 
• 1594-20-3 dehydrohumulinic acid 
• 92051-58-6 5,8-Dihydroxy-2,2-dimethyl-8-(3-methyl-but-2-enyl)-6-(3-methyl-butyryl)-2,3,4,8-tetrahydro-chromen-7-one 
• 92051-62-2 8,10-Dihydroxy-2,2-dimethyl-9-(3-methyl-but-2-enyl)-7-(3-methyl-butyryl)-1-oxa-spiro[4.5]deca-7,9-dien-6-one 
• 92051-59-7 6,7-Dihydroxy-2,2-dimethyl-6-(3-methyl-but-2-enyl)-8-(3-methyl-butyryl)-2,3,4,6-tetrahydro-chromen-5-one 
• 24183-31-1 (+/-)-3,4r-dihydroxy-2-isovaleryl-5t-(3-methyl-but-2-enyl)-cyclopent-2-enone 

Relevant academic research and scientific papers

Conversion of deoxyhumulone into the HOP α-acid humulone

In the final step of the biosynthesis of hop bitter acids an oxidation leads to the formation of α-acids. A method was set up to analyse the bitter acids in the presence of proteins, since proteins from a crude hop extract were found to interact with the

CIS 3,4-DIHYDROXY-2-(3-METHYLBUTANOYL)-5-(3-METHYLBUTYL)-4-(4-METHYLPENTANOYL)CYCLOPENT-2-EN-1-ONE DERIVATIVES, SUBSTANTIALLY ENANTIOMERICALLY PURE COMPOSITIONS AND METHODS

The present application provides cis 3,4-dihydroxy-2-(3-methylbutanoyl)-5-(3-methylbutyl)-4-(4-methylpentanoyl)cyclopent-2-en-1-one derivatives and substantially enantiomerically pure compositions thereof. These derivatives include (+)-(4S,5R)-3,4-dihydro

Method of acylation of phloroglucinol

A method of acylation of phloroglucinol in the presence of a Friedel Crafts catalyst which is effected in the presence of nitromethane and dichloromethane so as to produce an acylphloroglucinol. The acylphloroglucinol is reacted with a compound selected f

Hydroperoxy-desoxyhumulones

Humulones (I) are made by subjecting desoxyhumulones (II) to oxidation to form novel hydroperoxides (III) and reducing the latter. The humulones are used to make known isohumulones (IV) which are bitter substances useful in the beverage industry.