27320-99-6

Basic information

• Product Name: 7-Chloro-2H-1,4-benzoxazin
• Synonyms: 7-Chloro-2H-1,4-benzoxazin;7-Chloro-2H-1,4-benzoxazine;7-chloro-2H-benzo[b][1,4]oxazine;7-Chloro-2H-benzo[b][1,4]oxazin-3(4H)
• CAS NO: 27320-99-6
• Molecular Formula: C₈H₆ClNO₂
• Molecular Weight: 183.6
• Mol File: 27320-99-6.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 367.766 °C at 760 mmHg
• Flash Point: 176.219 °C
• Appearance: /
• Density: 1.393 g/cm³
• Vapor Pressure: 0.00115mmHg at 25°C
• Refractive Index: 1.612
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 7-Chloro-2H-1,4-benzoxazin(CAS DataBase Reference)
• NIST Chemistry Reference: 7-Chloro-2H-1,4-benzoxazin(27320-99-6)
• EPA Substance Registry System: 7-Chloro-2H-1,4-benzoxazin(27320-99-6)

Safety Data

• Hazardous Substances Data: 27320-99-6(Hazardous Substances Data)

Usage

General Description

7-Chloro-2H-1,4-benzoxazin, also known as Cl-BZ, is a chemical compound belonging to the benzoxazinoid family. It is a natural product found in plants such as maize and other grasses, and is known for its potent antimicrobial and allelopathic properties. It has been extensively studied for its role in plant defense mechanisms and its potential as a natural herbicide. Additionally, 7-Chloro-2H-1,4-benzoxazin has been investigated for its potential as a pharmaceutical agent due to its reported anti-inflammatory and anticancer properties. It has also been studied for its potential use in pest control and as an environmentally friendly alternative to synthetic pesticides.

InChI:InChI=1/C8H6ClNO/c9-6-1-2-7-8(5-6)11-4-3-10-7/h1-3,5H,4H2

Upstream product

• 37682-31-8 ethyl o-nitrophenoxyacetate 
• 771-26-6 4-hydroxy-2H-1,4-benzoxazin-3-one 
• 28443-50-7 2-amino-5-chlorophenol 
• 79-04-9 chloroacetyl chloride 
• 611-07-4 5-chloro-2-nitrophenol 
• 598-21-0 2-Bromoacetyl bromide 
• 120-83-2 2,4-dichlorophenol 
• 79-07-2 Chloroacetamide 
• 138035-65-1 7-chloro-4-hydroxy-2H-1,4-benzoxazin-3(4H)-one 
• 5466-88-6 3,4-dihydro-3-oxo-2H-1,4-benzoxazine 
• 1878-87-1 2-nitrophenoxyacetic acid 
• 824-39-5 sodium o-nitrophenate 

Downstream Products

• 1307844-95-6 C₂₀H₁₈Cl₂N₄O₂S 

Relevant articles and documents

Synthesis and Herbicidal Activity of Pyrido[2,3-d]pyrimidine-2,4-dione-Benzoxazinone Hybrids as Protoporphyrinogen Oxidase Inhibitors

To search for new protoporphyrinogen oxidase (PPO, EC 1.3.3.4) inhibitors with improved bioactivity, a series of novel pyrido[2,3-d]pyrimidine-2,4-dione-benzoxazinone hybrids, 9-13, were designed and synthesized. Several compounds with improved tobacco PP

Microwave-assisted synthesis of benzo-[1,4]-oxazinones using MeO-PEG-OMe as solvent

Efficient one-pot microwave-assisted synthesis of various benzo-[1,4]-oxazinones via Smiles rearrangement is described. Treatment of 2-chloroacetamide, substituted 2-chlorophenols and cesium carbonate in MeO-PEG-OMe (2,000) as solvent afforded the corresp

Electrochemical reduction of o-nitrophenoxy compounds: an access to 2H-1,4-benzoxazine derivatives

The electrochemical behavior of o-nitrophenoxyacetophenone, o-nitrophenoxyacetic acid and some related compounds (methyl ester, amide, nitrile) has been investigated in protic media.Controlled potential reductions allow the preparation of 2H-1,4-benzoxazine derivatives from the cyclization of the corresponding phenylhydroxylamines, but the latter can also disproportionate.In some cases, a retrocyclization was observed in warm acidic media, followed by a rearrangement of the parent phenylhydroxylamine. controlled potential electroreductions / 2H-1,4-benzoxazines / cyclic hydroxamic acid / lactam