3051-09-0 Usage
Uses
Different sources of media describe the Uses of 3051-09-0 differently. You can refer to the following data:
1. Indicator for complexometric titrations.
2. Murexide is used as a complexometric indicator in analytical chemistry for complexometric titrations of calcium, copper nickel and cobalt. It is an inhibitor of dihydrofolate reductase. Further, it acts as an enhancer of sonochemical destruction of chlorinated hydrocarbon pollutants.
Purification Methods
The sample may be grossly contaminated with uramil, alloxanthine, etc., and may be difficult to purify. It is better to synthesise it from pure alloxanthine [Davidson J Am Chem Soc 58 1821 1936]. Recrystallise it from water. [Kuhn & Lyman Chem Ber 69 1547 1936, Beilstein 25 I 709, 25 III/IV 4236.]
Check Digit Verification of cas no
The CAS Registry Mumber 3051-09-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,0,5 and 1 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 3051-09:
(6*3)+(5*0)+(4*5)+(3*1)+(2*0)+(1*9)=50
50 % 10 = 0
So 3051-09-0 is a valid CAS Registry Number.
InChI:InChI=1/C8H5N5O6.H3N/c14-3-1(4(15)11-7(18)10-3)9-2-5(16)12-8(19)13-6(2)17;/h1H,(H2,10,11,14,15,18)(H2,12,13,16,17,19);1H3
3051-09-0Relevant articles and documents
Compound instability in dimethyl sulphoxide, case studies with 5-aminopyrimidines and the implications for compound storage and screening
Prochazkova, Eliska,Jansa, Petr,Brezinova, Anna,Cechova, Lucie,Mertlikova-Kaiserova, Helena,Holy, Antonin,Dracinsky, Martin
supporting information, p. 6405 - 6409 (2012/11/07)
The oxidation reactions of 5-aminopyrimidine derivatives in dimethyl sulphoxide (DMSO) were studied. The DMSO solutions of the studied compounds became deeply coloured within a few hours or days. The oxidation products can undergo further condensation reactions with the starting pyrimidines to yield bipyrimidines and/or pyrimidopteridines. The reaction mechanism of the oxidation-condensation reaction was also supported by reactions of the 5-aminopyrimidines with alloxan (2,4,5,6-tetraoxopyrimidine). DMSO is often used as the solvent in in vitro tests of biological activities, but it is also an oxidising agent and may react with solute molecules and significantly affect the quality of the generated biochemical data.
