28864-27-9

Upstream product

• 98-88-4 benzoyl chloride 
• 141-78-6 ethyl acetate 
• 1904-58-1 anthranilic acid hydrazide 
• 65-85-0 benzoic acid 
• 118-48-9 isatoic anhydride 
• 613-94-5 benzoic acid hydrazide 
• 5344-90-1 2-Aminobenzyl alcohol 
• 93-89-0 benzoic acid ethyl ester 

Downstream Products

• 14663-55-9 3-benzoylamino-3H-quinazolin-4-one 
• 23047-95-2 2-(o-aminophenyl)-5-phenyl-1,3,4-oxadiazole 
• 118-92-3 anthranilic acid 
• 1429643-26-4 N-(2-(4-hydroxy-3-methoxyphenyl)-4-oxo-1,4-dihydroquinazolin-3(2H)-yl)benzamide 
• 1429643-12-8 C₂₃H₁₉N₃O₂ 
• 6761-27-9 3-benzoylamino-2-(3-nitro-phenyl)-3H-quinazolin-4-one 
• 856091-68-4 N-[2-(4-chloro-phenyl)-4-oxo-4H-quinazolin-3-yl]-benzamide 
• 930797-92-5 benzoic N'-[2-(ethoxyalylamino)benzoyl]hydrazide N-hydroxyamide 
• 930797-87-8 ethyl 3-(benzoylamino)-4-oxo-3,4-dihydroquinazoline-2-carboxylate 
• 930797-94-7 3-(benzoylamino)-4-oxo-3,4-dihydroquinazoline-2-carboxylic acid N-hydroxyamide 

Relevant academic research and scientific papers

Synthesis, Characterization, and Antimicrobial Activity of a Series of 2-(5-Phenyl-1,3,4-oxadiazol-2-yl)-N-[(1-aryl-1H-1,2,3-triazol-4-yl)methyl]anilines Using Click Chemistry

series of new triazolyl derived 1,3,4-oxadiazoles 7a–7l is synthesized with high yields by coppercatalyzed alkyne–azide cycloaddition reaction between a variety of substituted aryl/alkyl azides and 2-(5-phenyl-1,3,4-oxadiazol-2-yl)aniline. Structures of intermediates and the final compounds are confirmed by FTIR, 1H and 13C NMR, and Mass spectra. The synthesized compounds demonstrate moderate antibacterial activity and potent antifungal activity against the tested strains.

Unusual Acid- and Base-Catalyzed C-N Bond Formation Approach through Reaction of Chromonyl Meldrum's Acid and Nitrogen Binucleophiles

Reaction of chromonyl Meldrum's acid and N-substituted 2-aminobenzamides was studied in the presence of acidic and basic catalysts. The use of methanesulfonic acid as a catalyst in this reaction led to the synthesis of chromonyl quinazolinones through employing Meldrum's acid as a carbon leaving group. However, in the presence of basic catalyst, this reaction gave functionalized 2-pyridones.

Synthesis of 2-R-3-Hydroxy[1,2,4]triazino[6,1-b]-quinazoline-4,10-diones

A preparation method was developed for [1,2,4]triazino[6,1-b]quinazoline-4, 10-diones using isatoic anhydride, carboxylic acids hydrazides, ethyl oxalyl chloride, and hydroxylamine. Pleiades Publishing, Inc. 2006.

Reactions of N′-acyl- and N′-tosyl-substituted hydrazides of 2-aminobenzoic acid with carbonyl compounds

The reactions of N′-acyl and N′-tosyl-substituted hydrazides of 2-aminobenzoic acid with aliphatic, aromatic, and heterocyclic aldehydes or aliphatic ketones afforded 3-acyl- and 3-tosylamido-1,2-dihydroquinazolin-4-one derivatives, respectively. The stru

Reaction of 2-Aminobenzoylhydrazines with Carboxylic Acids: Formation of Quinazolin-4(3H)-one, 1,3,4-Oxadiazole and 1,3,4-Benzotriazepin-5-one Derivatives

Reactions of 2-aminobenzoylhydrazines with aliphatic acids give 1-(2'-acylaminobenzoyl)-2-acylhydrazines (4) which are cyclised to 3-amino-2-alkylquinazolin-4(3H)-ones (6).Aromatic acids react with 2-aminobenzoylhydrazines to give a mixture of 1-(2'-amino