3213-50-1

Basic information

• Product Name: ethyl cyano(cyclohexyl)acetate
• Synonyms: Cyclohexaneacetic acid, .alpha.-cyano-, ethyl ester; cyclohexaneacetic acid, alpha-cyano-, ethyl ester; Ethyl cyano(cyclohexyl)acetate
• CAS NO: 3213-50-1
• Molecular Formula: C₁₁H₁₇NO₂
• Molecular Weight: 195.2582
• Mol File: 3213-50-1.mol
• Article Data: 17

Chemical Properties

• Boiling Point: 307.7°C at 760 mmHg
• Flash Point: 142.9°C
• Density: 1.036g/cm³
• Vapor Pressure: 0.000713mmHg at 25°C
• Refractive Index: 1.469
• CAS DataBase Reference: ethyl cyano(cyclohexyl)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl cyano(cyclohexyl)acetate(3213-50-1)
• EPA Substance Registry System: ethyl cyano(cyclohexyl)acetate(3213-50-1)

Safety Data

• Hazardous Substances Data: 3213-50-1(Hazardous Substances Data)

Usage

General Description

Ethyl cyano(cyclohexyl)acetate is a chemical compound with the molecular formula C11H15NO2. It is a colorless to pale yellow liquid with a fruity odor, commonly used as a flavoring agent in the food and beverage industry. ethyl cyano(cyclohexyl)acetate is also used in the production of pharmaceuticals and as an intermediate in organic synthesis. Ethyl cyano(cyclohexyl)acetate is a versatile compound, with applications in multiple industries, and is known for its pleasant aroma and taste-enhancing properties. It is important to handle this chemical with care, as it may be harmful if swallowed, inhaled, or in contact with skin.

Upstream product

• 542-18-7 cyclohexyl chloride 
• 18852-51-2 sodium cyanoacetic acid ethyl ester 
• 626-62-0 Cyclohexyl iodide 
• 6802-76-2 ethyl 2-cyano-2-cyclohexylideneacetate 
• 108-94-1 cyclohexanone 
• 105-56-6 ethyl 2-cyanoacetate 
• 108-85-0 1-bromocyclohexane 
• 110-83-8 cyclohexene 
• 4435-14-7 2-cyclohexylacetonitrile 
• 105-58-8 Diethyl carbonate 
• 108-93-0 cyclohexanol 
• 108-95-2 phenol 

Downstream Products

• 4354-67-0 2-cyclohexylmalonic acid 
• 4435-14-7 2-cyclohexylacetonitrile 
• 5292-21-7 Cyclohexylacetic acid 
• 408536-63-0 2-cyano-2-cyclohexylbutyric acid ethyl ester 
• 4354-64-7 2-cyclohexyl-malonamic acid 
• 93116-94-0 Cyclohexylmalon-amidoxim-hydroxamsaeure 
• 13275-31-5 ethyl cyclohexyloxoacetate 
• 91690-99-2 Propyl-cyclohexyl-malonamidsaeure 
• 91690-98-1 Isopropyl-cyclohexyl-malonamidsaeure 
• 5452-75-5 ethyl 2-cyclohexylacetate 
• 860256-59-3 benzyl(cyano)(cyclohexyl)acetic acid ethyl ester 
• 95834-44-9 cyano(cyclohexyl)(methyl)acetic acid ethyl ester 

Relevant articles and documents

Photo-induced anti-Markovnikov hydroalkylation of unactivated alkenes employing a dual-component initiator

Metal-free anti-Markovnikov hydroalkylation of unactivated alkenes with cyanoacetate has been developed, featuring the use of a dual-component initiator containing an organic photocatalyst and a radical precursor. When combined, the two components can und

AlCl3 catalyzed coupling of: N-benzylic sulfonamides with 2-substituted cyanoacetates through carbon-nitrogen bond cleavage

A new cross-coupling reaction of N-benzylic sulfonamides with 2-substituted cyanoacetates for the synthesis of 2-substituted benzylbenzene was reported. In the presence of AlCl3, a broad range of N-benzylic sulfonamides reacted smoothly with 2-substituted cyanoacetates to afford structurally diverse benzylbenzenes in moderate to excellent yields. The conversion could be enlarged to gram-scale efficiently. The practicability of this approach was further manifested in the synthesis of a related bioactive agent with high anti-inflammatory activity.

COMPOUNDS USEFUL AS MODULATORS OF TRPM8

The present invention includes compounds useful as modulators of TRPM8, such as compounds of Formulae (Ia), (Ib) and (Ic), and the subgenus and species thereof; personal products containing those compounds; and the use of those compounds and the personal products, particularly the use of increasing or inducing chemesthetic sensations, such as cooling or cold sensations.