3440-46-8

Basic information

• Product Name: 2-Methylquinazolin-4-aMine
• Synonyms: 2-Methylquinazolin-4-aMine
• CAS NO: 3440-46-8
• Molecular Formula: C₉H₉N₃
• Molecular Weight: 159.18786
• EINECS: -0
• Mol File: 3440-46-8.mol
• Article Data: 13

Chemical Properties

• Melting Point: 218-219 °C
• Boiling Point: 218-219 °C
• Appearance: /
• Density: 1.238±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C(protect from light)
• PKA: 7.63±0.50(Predicted)
• CAS DataBase Reference: 2-Methylquinazolin-4-aMine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Methylquinazolin-4-aMine(3440-46-8)
• EPA Substance Registry System: 2-Methylquinazolin-4-aMine(3440-46-8)

Safety Data

• Hazardous Substances Data: 3440-46-8(Hazardous Substances Data)

Usage

General Description

2-Methylquinazolin-4-amine is a chemical compound with the molecular formula C9H9N3. It is a derivative of quinazoline and belongs to the class of organic compounds known as quinazolines. 2-Methylquinazolin-4-aMine is a pale yellow solid that is insoluble in water but soluble in organic solvents. 2-Methylquinazolin-4-amine is used in the synthesis of pharmaceuticals and other organic compounds. It has potential applications in the fields of medicinal chemistry and drug development due to its structural features and biological activities.

Upstream product

• 82216-70-4 3-(2-benzylaminophenyl)-5-methyl-1,2,4-oxadiazole 
• 75-05-8 acetonitrile 
• 1885-29-6 anthranilic acid nitrile 
• 2719-08-6 methyl 2-(acetylamino)benzoate 
• 61844-46-0 5-methyl<1,2,4>oxadiazolo<2,3-c>quinazolin-2-one 
• 78-39-7 Triethyl orthoacetate 
• 2042-37-7 o-cyanobromobenzene 
• 124-42-5 acetamidine hydrochloride 
• 75-36-5 acetyl chloride 
• 64-19-7 acetic acid 
• 119392-86-8 N-acetyl-2-benzylaminobenzonitrile 
• 5589-62-8 2-(benzylamino)benzonitrile 
• 119392-83-5 1-benzyl-2-methyl-4(1H)-quinazolone oxime 
• 108732-43-0 2-Methyl-3-oxy-1,2-dihydro-quinazolin-4-ylamine 

Relevant articles and documents

Dawson heteropolyacid: A green, eco-friendly, and reusable catalyst for one-pot synthesis of 4-aminoquinazolines

A new multicomponent synthesis of 4-aminoquinazolines from the reaction of anthranilonitrile, acylchlorides, and ammonium acetate in the presence of catalytic amounts of Dawson-type heteropolyacids (HPAs) is reported. The catalytic performance of different forms of Dawson-type HPAs, H6 P2M18O62 (M = WVI, MoVI) and mixed addenda forms (M = CoII, CuII, NiII, MnIII) were compared and in all cases, maximum of yield was observed by using H6P2W18O62 as catalyst. The plausible mechanism was estimated. In all cases, the Dawson catalyst was easily recovered and recycled with retention of their initial structure and activity. The effects of reaction conditions have been studied and the results showed yields of reaction are good to excellent. Copyright Taylor and Francis Group, LLC.

Efficient copper-catalyzed synthesis of 4-aminoquinazoline and 2,4-diaminoquinazoline derivatives

We have developed an efficient copper-catalyzed method for the synthesis of 4-aminoquinazoline and 2,4-diaminoquinazoline derivatives via reactions of substituted 2-bromobenzonitriles with amidines or guanidine, and the method is of economical and practic

An efficient method to prepare 4-aminoquinazolines: Potential application to conformation-restricted bleomycin analogs

(Chemical Equation Presented) To enhance the iron-chelating ability of P-3A, 4-aminoquinazolines were designed as conformation-restricted bleomycin analogs. An efficient method was developed to prepare the 4-aminoquinazoline heterocyclic nucleus, which en