349403-39-0

Basic information

• Product Name: 2-Bromo-N-butylbenzamide
• Synonyms: 2-Bromo-N-butylbenzamide;N-Butyl 2-bromobenzamide
• CAS NO: 349403-39-0
• Molecular Formula: C₁₁H₁₄BrNO
• Molecular Weight: 256.14
• Product Categories: blocks;Bromides;Carboxes
• Mol File: 349403-39-0.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 355.7±25.0 °C(Predicted)
• Appearance: /
• Density: 1.310±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 14.25±0.46(Predicted)
• CAS DataBase Reference: 2-Bromo-N-butylbenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Bromo-N-butylbenzamide(349403-39-0)
• EPA Substance Registry System: 2-Bromo-N-butylbenzamide(349403-39-0)

Safety Data

• Hazardous Substances Data: 349403-39-0(Hazardous Substances Data)

Usage

General Description

2-Bromo-N-butylbenzamide is an organic compound with the chemical formula C11H14BrNO. It belongs to the class of benzamides, which are derivatives of benzoic acid with an amide functional group. This particular compound is characterized by the presence of a bromine atom and a butyl group attached to the benzamide core. It is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. The compound may also have potential applications in organic chemistry research, particularly in the development of new chemical reactions and processes. Overall, 2-Bromo-N-butylbenzamide is a versatile chemical that has various uses in the field of industrial and scientific research.

Upstream product

• 79985-00-5 2-bromo-benzoyl bromide 
• 109-73-9 N-butylamine 
• 6630-33-7 ortho-bromobenzaldehyde 
• 98-88-4 benzoyl chloride 
• 2782-40-3 N-butylbenzamide 
• 88-65-3 2-bromobenzoic-acid 
• 7154-66-7 2-bromobenzoic acid chloride 

Downstream Products

• 1127897-04-4 (Z)-3-benzylidene-2-butyl-2,3-dihydro-isoindol-1-one 
• 4299-07-4 2-butyl-1,2-benzothiazolin-3-one 
• 67796-16-1 2-phenyl-3-n-butylquinazoline-4(3H)-one 
• 34497-13-7 2-butyl-1-oxo-3-phenyl-1,2-dihydroisoquinoline 
• 1425606-06-9 N-butyl-3-phenylisoquinolin-1-amine 
• 23023-35-0 3-phenylisoquinolin-1-ylamine 

Relevant articles and documents

Synthesis of pyrimido[2,1-a]isoindolone and isoindolo[2,1-a]quinazolinoneviaintramolecular aza-Prins type reaction

A novel aza-Prins type cyclization reaction involvingN-acyliminium ions and amides is reported for the synthesis of tetrahydropyrimido[2,1-a]isoindole-2,6-dione and 6,6a-dihydroisoindolo[2,1-a]quinazoline-5,11-dione derivatives in excellent yields. The strategy features inexpensive reagents, mild reaction conditions, and metal-free synthesis of N-heterocyclic frameworks. Further, post-synthetic modification results in the unprecedented formation of its triazole, tetracyclic diazacyclopenta[def]phenanthrene-1,4(9a1H)-dione and carbonyl derivatives.

Convenient metal-free direct oxidative amidation of aldehyde using dibromoisocyanuric acid under mild conditions

A facile method for the direct synthesis of amides from aldehydes is described. Amide bonds were synthesized by an oxidative amidation in the presence of dibromoisocyanuric acid (DBI). Treatment of aromatic and aliphatic aldehydes with dibromoisocyanuric acid generated acyl bromide intermediates, which were employed to react with a variety of secondary and primary amines to give amides. Through this reaction method, various amides were synthesized directly from aldehydes under mild conditions in high yields and short times. This facile and efficient procedure provides potential strategy for the direct synthesis of amides from aldehydes.

Synthesis of 1-aminoisoquinolines by gold(III)-mediated domino reactions from 2-alkynylbenzamides and ammonium acetate

A facile synthetic route toward pharmaceutically interesting 1-aminoisoquinoline derivatives by gold(III)-mediated domino reactions is described. This synthetic protocol starts from readily available 2-alkynylbenzamides and ammonium acetate and takes plac