35450-37-4

Basic information

• Product Name: METHYL 3-BROMO-4-METHOXYBENZOATE 98
• Synonyms: METHYL 3-BROMO-4-METHOXYBENZOATE 98;METHYL 3-BROMO-4-METHOXYBENZOATE, PURISS, 98%;3-Bromo-4-methoxybenzoic Acid Methyl Ester Methyl 3-Bromo-p-anisate 3-Bromo-p-anisic Acid Methyl Ester;4-Methoxy-3-BroMo Benzoic Acid Methyl Ester
• CAS NO: 35450-37-4
• Molecular Formula: C₉H₉BrO₃
• Molecular Weight: 245.071
• EINECS: 1312995-182-4
• Product Categories: Aromatic Esters;Acids & Esters;Anisoles, Alkyloxy Compounds & Phenylacetates;Bromine Compounds;Building Blocks;C8 to C9;Carbonyl Compounds;Chemical Synthesis;Esters;Organic Building Blocks
• Mol File: 35450-37-4.mol
• Article Data: 27

Chemical Properties

• Melting Point: 98-100 °C(lit.)
• Boiling Point: 298.1 °C at 760 mmHg
• Flash Point: 134.1 °C
• Appearance: /
• Density: 1.463 g/cm³
• Vapor Pressure: 0.00129mmHg at 25°C
• Refractive Index: 1.537
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: soluble in Toluene
• CAS DataBase Reference: METHYL 3-BROMO-4-METHOXYBENZOATE 98(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 3-BROMO-4-METHOXYBENZOATE 98(35450-37-4)
• EPA Substance Registry System: METHYL 3-BROMO-4-METHOXYBENZOATE 98(35450-37-4)

Safety Data

• Hazard Codes: T
• Statements: 25
• Safety Statements: 45
• RIDADR: UN 2811 6.1/PG 3
• WGK Germany: 3
• Hazardous Substances Data: 35450-37-4(Hazardous Substances Data)

Usage

General Description

Methyl 3-bromo-4-methoxybenzoate 98 is a chemical compound commonly used in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals. It is a colorless to pale yellow liquid with a molecular formula of C9H9BrO3 and a molecular weight of 241.07 g/mol. METHYL 3-BROMO-4-METHOXYBENZOATE 98 is often utilized as an intermediate in organic synthesis, particularly in the preparation of various esters and ethers. It is also known for its potential application in the development of new drugs or medicinally active compounds. With a purity of 98%, this chemical is considered to be of high quality and suitable for a wide range of research and industrial purposes.

InChI:InChI=1/C9H9BrO3/c1-12-8-4-3-6(5-7(8)10)9(11)13-2/h3-5H,1-2H3

Upstream product

• 121-98-2 methyl 4-methoxybenzoate 
• 67-56-1 methanol 
• 22002-45-5 2-bromo-4-methylanisole 
• 99-96-7 4-hydroxy-benzoic acid 
• 34841-06-0 3-bromo-4-methoxybenzylaldehyde 
• 14348-41-5 3-bromo-4-hydroxy-benzoic acid 
• 74-88-4 methyl iodide 
• 99-58-1 3-bromo-4-methoxybenzoic acid 
• 99-76-3 methyl 4-hydroxylbenzoate 
• 105-13-5 4-Methoxybenzyl alcohol 
• 123-11-5 4-methoxy-benzaldehyde 
• 7726-95-6 bromine 
• 64-19-7 acetic acid 
• 77-78-1 dimethyl sulfate 

Downstream Products

• 873980-71-3 4,4'-dimethoxy-3,3'-oxy-di-benzoic acid dimethyl ester 
• 38493-59-3 (3-bromo-4-methoxy-phenyl)-methanol 
• 89978-72-3 2-bromo-4-(bromomethyl)-1-methoxybenzene 
• 443776-90-7 4-methoxy-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzaldehyde 
• 1426580-94-0 1,7-bis-(3-bromo-4-methoxyphenyl)-heptan-3-one 
• 34841-06-0 3-bromo-4-methoxybenzylaldehyde 
• 1426580-91-7 2-[4-(3-bromo-4-methoxyphenyl)-but-3-enyl]-2-methyl-[1,3]dioxolane 
• 1426580-97-3 2-[4-(3-bromo-4-methoxyphenyl)-but-3-enyl]-2-methyl-[1,3]dioxolane 
• 1432055-45-2 2-bromo-4-(hepta-1,6-dien-4-yl)-1-methoxybenzene 
• 1432055-46-3 2-bromo-4-(cyclopent-3-en-1-yl)-1-methoxybenzene 
• 1432055-44-1 4-(3-bromo-4-methoxyphenyl)hepta-1,6-dien-4-ol 
• 181136-33-4 3-bromo-4-methoxybenzohydrazide 
• 21962-50-5 5-formyl-2-methoxybenzonitrile 
• 310424-35-2 5-hydroxymethyl-2-methoxy-benzonitrile 

Relevant articles and documents

Synthetic Strategies towards Imidazopyridinones and 7-Azaoxindoles and their Evaluation as Antibacterial Agents

Imidazopyridinones and 7-azaoxindoles are two classes of heterocyclic compounds with only limited previous use in organic and medicinal chemistry. Various synthetic methods and routes have been evaluated to identify safe and robust chemistry to advanced i

Ni-NiO heterojunctions: a versatile nanocatalyst for regioselective halogenation and oxidative esterification of aromatics

Herein, we report a facile method for the synthesis of Ni-NiO heterojunction nanoparticles, which we utilized for the nuclear halogenation reaction of phenol and substituted phenols usingN-bromosuccinimide (NBS). A remarkablepara-selectivity was achieved for the halogenated products under semi-aqueous conditions. Interestingly, blocking of thepara-position of phenol offeredortho-selective halogenation. In addition, the Ni-NiO nanoparticles catalyzed the oxidative esterification of carbonyl compounds with alcohol, diol or dithiol in the presence of a catalytic amount of NBS. It was observed that the aromatic carbonyls substituted with an electron-donating group favoured nuclear halogenation, whereas an electron-withdrawing group substitution in carbonyl compounds facilitated the oxidation reaction. In addition, the catalyst was magnetically separated and recycled 10 times. The tuned electronic structure at the Ni-NiO heterojunction controlled selectivity and activity as no suchpara-selectivity was observed with commercially available NiO or Ni nanoparticles.

A convenient and efficient H2SO4-promoted regioselective monobromination of phenol derivatives using N-bromosuccinimide

A convenient, rapid H2SO4-promoted regioselective monobromination reaction with N-bromosuccinimide was developed. The desired para-monobrominated or ortho-monobrominated products of phenol derivatives were obtained in good to excellent yields with high selectivity. Regioselective chlorination and iodination were also achieved in the presence of H2SO4 using N-chlorosuccinimide and N-iodosuccinimide, respectively.