35750-24-4

Basic information

• Product Name: methyl 4-(prop-2-en-1-yloxy)benzoate
• Synonyms: RARECHEM AL BF 0237;Methyl 4-(allyloxy)benzoate;Methyl 4-(prop-2-en-1-yloxy)benzoate
• CAS NO: 35750-24-4
• Molecular Formula: C₁₁H₁₂O₃
• Molecular Weight: 192.2112
• Mol File: 35750-24-4.mol
• Article Data: 41

Chemical Properties

• Boiling Point: 289.6°C at 760 mmHg
• Flash Point: 117°C
• Density: 1.071g/cm³
• Vapor Pressure: 0.00218mmHg at 25°C
• Refractive Index: 1.51
• CAS DataBase Reference: methyl 4-(prop-2-en-1-yloxy)benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 4-(prop-2-en-1-yloxy)benzoate(35750-24-4)
• EPA Substance Registry System: methyl 4-(prop-2-en-1-yloxy)benzoate(35750-24-4)

Safety Data

• Hazardous Substances Data: 35750-24-4(Hazardous Substances Data)

Upstream product

• 556-56-9 allyl iodid 
• 99-76-3 methyl 4-hydroxylbenzoate 
• 106-95-6 allyl bromide 
• 107-05-1 3-chloroprop-1-ene 
• 67-56-1 methanol 
• 27914-60-9 4-allyloxybenzoic acid 
• 99-96-7 4-hydroxy-benzoic acid 
• 106-93-4 ethylene dibromide 
• 107-18-6 allyl alcohol 
• 40663-68-1 4-(2-propenyloxy)benzaldehyde 
• 619-42-1 4-methoxycarbonylphenyl bromide 

Downstream Products

• 53596-60-4 methyl 3-allyl-4-hydroxybenzoate 
• 114544-58-0 methyl trans-4-<<3-(4-chlorophenyl)-2-methyl-3-<(1H-1,2,4-triazol-1-yl)methyl>isoxazolidin-5-yl>methoxy>benzoate 
• 114544-58-0 methyl cis-4-<<3-(4-chlorophenyl)-2-methyl-3-<(1H-1,2,4-triazol-1-yl)methyl>isoxazolidin-5-yl>methoxy>benzoate 
• 99-76-3 methyl 4-hydroxylbenzoate 
• 99-96-7 4-hydroxy-benzoic acid 
• 27914-60-9 4-allyloxybenzoic acid 
• 918164-16-6 methyl 4-acetoxy-3-(3-methylbut-2-enyl)benzoate 
• 1138-41-6 4-hydroxy-3-prenylbenzoic acid 
• 92194-92-8 4-(chlorocarbonyl)-2-(3-methylbut-2-en-1-yl)phenyl acetate 
• 1990-85-8 4-acetoxy-3-(3-methylbut-2-en-1-yl)benzoic acid 
• 918164-15-5 methyl 4-acetoxy-3-allylbenzoate 
• 124172-25-4 cis-4-<<3-(4-chlorophenyl)-2-methyl-3-<(1H-1,2,4-triazol-1-yl)methyl>isoxazolidin-5-yl>methoxy>benzoic acid 
• 219763-06-1 2-Methyl-1-benzofuran-5-carboxylic acid 
• 117379-97-2 5-methoxycarbonyl-2-methylbenzofuran 

Relevant articles and documents

Electro-Oxidative Selective Esterification of Methylarenes and Benzaldehydes

A mild and green electro-oxidative protocol to construct aromatic esters from methylarenes and alcohols is herein reported. Importantly, the reaction is free of metals, chemical oxidants, bases, acids, and operates at room temperature. Moreover, the design of the electrolyte was found critical for the oxidation state and structure of the coupling products, a rarely documented effect. This electro-oxidative coupling process also displays exceptional tolerance of many fragile easily oxidized functional groups such as hydroxy, aldehyde, olefin, alkyne, as well as neighboring benzylic positions. The enantiomeric enrichment of some chiral alcohols is moreover preserved during this electro-oxidative coupling reaction, making it overall a promising synthetic tool.

DEUTERIUM-ENRICHED SUBSTITUTED PHENOXYPHENYL ACETIC ACIDS AND ACYLSULFONAMIDES

The present invention is concerned with deuterium-enriched substituted phenoxy-(3, 4-methylenedioxy)phenylacetic acid and acylsulfonamide derivatives of general structural formula I, their optically active or pure enantiomers and diastereomers, and pharmaceutical salts thereof, Formula (I) These compounds have selective antagonist activity for endothelin receptors or both endothelin and angiotensin II receptors, and are useful in the treatment of diseases mediated by endothelin and angiotensin-II and their receptors.

2-Aryl benzazole derived new class of anti-tubercular compounds: Endowed to eradicate mycobacterium tuberculosis in replicating and non-replicating forms

The high mortality rate and the increasing prevalence of Mtb resistance are the major concerns for the Tuberculosis (TB) treatment in this century. To counteract the prevalence of Mtb resistance, we have synthesized 2-aryl benzazole based dual targeted molecules. Compound 9m and 9n were found to be equally active against replicating and non-replicating form of Mtb (MIC(MABA) 1.98 and 1.66 μg/ml; MIC(LORA) 2.06 and 1.59 μg/ml respectively). They arrested the cell division (replicating Mtb) by inhibiting the GTPase activity of FtsZ with IC50 values 45 and 64 μM respectively. They were also capable of kill Mtb in non-replicating form by inhibiting the biosynthesis of menaquinone which was substantiated by the MenG inhibition (IC50 = 11.62 and 7.49 μM respectively) followed by the Vit-K2 rescue study and ATP production assay.