36081-67-1

Usage

Uses

Used in Organic Synthesis:
Ethanedione, (2-bromophenyl)phenylis used as a building block in organic synthesis for the production of various organic compounds. Its unique structure allows for the creation of a wide range of chemical products, making it a versatile component in the synthesis process.
Used in Pharmaceutical Industry:
Ethanedione, (2-bromophenyl)phenylis used as a key intermediate in the development of pharmaceuticals. Its chemical properties enable the creation of new drug molecules with potential therapeutic applications, contributing to the advancement of medicine.
Used in Agrochemical Industry:
Ethanedione, (2-bromophenyl)phenylis used as a starting material in the synthesis of agrochemicals, such as pesticides and herbicides. Its unique structure allows for the development of more effective and environmentally friendly products, benefiting agricultural practices.
Used in Materials Science:
Ethanedione, (2-bromophenyl)phenylis used in the development of new materials with specific properties, such as high thermal stability or unique optical characteristics. Its chemical structure plays a crucial role in the design and synthesis of advanced materials for various applications in materials science.

Upstream product

• 2042-37-7 o-cyanobromobenzene 
• 583-55-1 1-Bromo-2-iodobenzene 
• 536-74-3 phenylacetylene 
• 19472-74-3 2-(2-bromophenyl)acetonitrile 
• 1431527-08-0 1-phenyl-3-(o-bromophenyl)-2,3-epoxy-1-propanone 
• 1605349-89-0 (2-bromophenyl)(3-phenyloxiran-2-yl)methanone 
• 18698-97-0 ortho-bromophenylacetic acid 
• 55116-09-1 2-bromophenylacetyl chloride 
• 54737-45-0 (E)-2-bromostilbene 
• 36081-80-8 1-(2'-bromophenyl)-3-phenylpropane-1,3-dione 
• 2142-69-0 2-bromophenyl methyl ketone 
• 16897-97-5 2-(2-bromophenyl)-1-phenyl-1-ethanone 
• 100-44-7 benzyl chloride 
• 693208-77-4 2-Bromphenylbenzyl-ketimin 

Downstream Products

• 1146729-43-2 syn-1-(2-bromophenyl)-2-phenylethane-1,2-diol 
• 61547-75-9 1,3-Bis-<2-(α,α,β,β-tetrafluorphenethyl)-phenyl>-harnstoff 
• 61547-71-5 [2-(1,1,2,2-Tetrafluoro-2-phenyl-ethyl)-phenyl]-carbamic acid methyl ester 

Relevant academic research and scientific papers

Tailoring the Molecular Properties with Isomerism Effect of AIEgens

It is challenging to achieve precise control on the properties of organic π-functional materials to widen their practical applications. On the other hand, the study of aggregation-induced emission luminogens (AIEgens) helps achieve such goals because of i

Two-Step One-Pot Synthesis of Unsymmetrical (Hetero)Aryl 1,2-Diketones by Addition-Oxygenation of Potassium Aryltrifluoroborates to (Hetero)Arylacetonitriles

An efficient one-pot two-step procedure for the synthesis of unsymmetrical (hetero)aryl 1,2-diketones has been developed. The reaction proceeds through a palladium-catalyzed nucleophilic addition of potassium aryltrifluoroborates to aliphatic nitriles followed by a copper-catalyzed aerobic benzylic C–H oxygenation using molecular oxygen as a green oxidant. This represents the first example of the direct synthesis of unsymmetrical diaryl 1,2-diketones from arylacetonitriles. This method utilizes inexpensive, stable, nontoxic, and readily available starting materials, is highly effective in the presence of both electron-rich and electron-poor nitriles and aryltrifluoroborates, and tolerates a wide variety of functional groups. The synthetic utility of this transformation was shown by increasing the scale of the reaction and by carrying out the one-pot protocol for the preparation of quinoxaline and benzimidazole derivatives. A plausible reaction mechanism has also been proposed.

ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME

The present disclosure relates to an organic electroluminescent compound and an organic electroluminescent device comprising the same. The organic electroluminescent compound of the present disclosure can provide an organic electroluminescent device havin

ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME

The present disclosure relates to an organic electroluminescent compound and an organic electroluminescent device comprising the same. By comprising the organic electroluminescent compound of the present disclosure, an organic electroluminescent device ha

Copper-catalyzed TEMPO oxidative cleavage of 1,3-diketones and β-keto esters for the synthesis of 1,2-diketones and α-keto esters

A copper-catalyzed efficient and practical method has been developed for the synthesis of 1,2-diketones and α-keto esters. TEMPO was used as a radical initiator and scavenger, oxidizing the cleavage of α-methylene of 1,3-diketones and β-keto esters to form 1,2-diketones and α-keto esters. This method provided a general way for the formation of 1,2-dicarbonyl compounds.

Selectfluor-Mediated Simultaneous Cleavage of C-O and C-C Bonds in α,β-Epoxy Ketones under Transition-Metal-Free Conditions: A Route to 1,2-Diketones

Selectfluor-mediated simultaneous cleavage of C-O and C-C bonds in α,β-epoxy ketones has been successfully achieved under transition-metal-free conditions. The reaction gives 1,2-diketone compounds in moderate to good yields involving a ring-opening/benzoyl rearrangement/C-C bond cleavage sequence under oxidative conditions.

Copper-catalyzed base-accelerated direct oxidation of C-H bond to synthesize benzils, isatins, and quinoxalines with molecular oxygen as terminal oxidant

We describe herein an efficient and general copper (II)-catalyzed base-accelerated oxidation of the C-H bond to synthesize benzils and isatins. With similar oxidation system an efficient one-pot procedure for the synthesis of quinoxaline derivatives was realized. The two protocols feature using molecular oxygen as terminal oxidant, low catalyst loading, wide substrate scope, and high functional-group tolerance.

One-pot, two-step desymmetrization of symmetrical benzils catalyzed by the methylsulfinyl (dimsyl) anion

An operationally simple one-pot, two-step procedure for the desymmetrization of benzils is herein described. This consists in the chemoselective cross-benzoin reaction of symmetrical benzils with aromatic aldehydes catalyzed by the methyl sulfinyl (dimsyl) anion, followed by microwave-assisted oxidation of the resulting benzoylated benzoins with nitrate, avoiding the costly isolation procedure. Both electron-withdrawing and electron-donating substituents may be accommodated on the aromatic rings of the final unsymmetrical benzil. the Partner Organisations 2014.

Asymmetric transfer hydrogenation of unsymmetrical benzils

In this paper, the asymmetric transfer hydrogenation of unsymmetrical benzils with m, p-substituents was conducted with a substrate/catalyst molar ratio of 100 at 40°C for 24 h to produce (S,S)-hydrobenzoins in good yields (76.2% to 97.1%) with high diastereomeric (syn/anti = 10.8 to 29.7/1) and enantiomeric purities (86.1%ee syn to 98.9%ee syn). Unfortunately, the unsymmetrical benzils with the o-substituents such as electron-donating (R = CH3, OCH3) and electron-withdrawing groups (R = F, Cl, CF3) resulted in poor yields (0% to 31.2%), even at 40°C for 72 h. These products had inefficient diastereoselectivities (syn/anti = 1.5 to 5.0/1) caused by steric effects. Furthermore, the results of a dynamic-kinetic study were used to propose a plausible reaction pathway of unsymmetrical benzil using 3-methoxy-1,2-diphenyl ethanedione as an example.

Facile and highly chemoselective synthesis of benzil derivatives via oxidation of stilbenes in an I2-H2O system

A facile and highly chemoselective protocol for the synthesis of benzil derivatives has been developed by oxidation of stilbenes in an I 2-H2O system under air. Notably, the method was applicable to 26 examples and provided up to 98% yield, avoiding the use of acid, metal catalysts and so on.