3762-39-8

Usage

Molecular Weight

213.12 g/mol

Functional Groups

Secondary alcohol, Bromine atom, Phenyl ring

Chirality

Chiral molecule

Physical State

Likely a liquid or solid at room temperature (exact state depends on temperature)

Solubility

Soluble in organic solvents like ethanol, methanol, and dichloromethane

Reactivity

Reacts with various reagents in organic synthesis

Applications

Reagent in organic synthesis
Pharmaceutical research
Synthesis of biologically active compounds
Building block for complex molecules
Precursor in pharmaceutical drug and agrochemical production
Potential applications in medicinal chemistry and drug discovery

Upstream product

• 21906-32-1 3-bromophenylacetone 
• 75-16-1 methylmagnesium bromide 
• 676-58-4 methylmagnesium chloride 
• 150529-73-0 methyl 2-(3-bromophenyl)acetatee 
• 558-30-5 2-methyl-1,2-epoxypropane 
• 108-36-1 1,3-dibromobenzene 
• 955369-44-5 3-(3-bromophenyl)-2,2-dimethyloxirane 
• 823-78-9 meta-bromobenzyl bromide 
• 67-64-1 acetone 

Downstream Products

• 955369-45-6 [3-(2-hydroxy-2-methylpropyl)phenyl]boronic acid 
• 808769-15-5 N-[2-(3-bromophenyl)-1,1-dimethylethyl]-2-chloroacetamide 
• 1346690-13-8 1-[3-(hydroxymethyl)phenyl]-2-methylpropan-2-ol 
• 1346690-14-9 3-(2-hydroxy-2-methylpropyl)benzyl methanesulphonate 
• 1418296-25-9 1-{3-[(3-{(Z)-1-fluoro-2-[4-(1,1,1-trifluoro-2-methylpropan-2-yl)phenyl]vinyl}-5-methyl-1H-pyrazol-1-yl)methyl]phenyl}-2-methylpropan-2-ol 
• 1346690-12-7 3-(2-hydroxy-2-methylpropyl)benzaldehyde 
• 808769-12-2 3-(2-tert-butoxycarbonylamino-2-methylpropyl)benzoic acid methyl ester 
• 808769-13-3 [2-(3-bromophenyl)-1,1-dimethylethyl]carbamic acid tert-butyl ester 
• 808769-11-1 methyl 3-(2-amino-2-methylpropyl)benzoate 
• 808769-14-4 1-(3-bromophenyl)-2-methylpropan-2-amine 
• 1754-71-8 Dimethyl-(3-brom-benzyl)-carbinylchlorid 

Relevant academic research and scientific papers

COMPOSITION HAVING A MUGUET ODOR

The present invention relates to a composition of matter comprising a) at least one compound of formula (I) in the form of any one of its isomers or a mixture thereof; wherein R1 represents a hydrogen atom or a C1-2 alkyl group; R2 represents a hydrogen atom or a methyl group; and R represents a group of formula –[CH2]nC(Me)2OH, wherein n is 1 or 2; said R being, relative to position 1, an ortho, meta or para substituent of the aromatic ring; and b) at least one compound of formula (II) in the form of any one of its isomers or a mixture thereof; wherein R1, R2 and R have the same meaning as defined in formula (I); said R being, relative to position 1, an ortho, meta or para substituent of the aromatic ring; their uses as perfuming ingredients as well as the composition and consumer product including such a composition of matter and the process to prepare it.

SUBSTITUTED OXADIAZOLYL PYRIDINONES AND OXADIAZOLYL PYRIDAZINONES AS HIF INHIBITORS

The present application relates to novel substituted 5-(1,2,4-oxadiazol-5-yl)pyridin-2-ones and 6-(1,2,4-oxadiazol-5-yl)pyridazin-3-ones, to processes for their preparation, to their use for the treatment and/or prevention of diseases and to their use for producing medicaments for treatment and/or prevention of diseases, in particular for treatment and/or prevention of hyperproliferative and angiogenic diseases and those diseases which arise from metabolic adaptation to hypoxic states. Such treatments can be effected in the form of monotherapy or else in combination with other medicaments or further therapeutic measures.

3-(Fluorovinyl)pyrazoles and their use

The present application relates to novel 3-(fluorovinyl)pyrazole derivatives, to processes for their preparation, to their use for treatment and/or prevention of diseases and to their use for the preparation of medicaments for treatment and/or prevention of diseases, in particular for treatment and/or prevention of hyperproliferative and angiogenic diseases and those diseases which arise from metabolic adaptation to hypoxic states. Such treatments can be carried out as monotherapy or also in combination with other medicaments or further therapeutic measures.

Dihydropyrazolopyrimidinone derivatives

The invention relates to compounds of a general formula (I): wherein Ar1 is an optionally-substituted aryl or heteroaromatic group; R1 is an optionally-substituted lower alkyl, lower alkenyl, lower alkynyl or cyclo-lower alkyl group, or is an aryl, aralkyl or heteroaromatic group optionally having a substituent; R2 is a hydrogen atom, a lower alkyl group, a lower alkenyl group or a lower alkynyl group, or is an aryl, aralkyl or heteroaromatic group optionally having a substituent; R3 is a hydrogen atom or a lower alkyl group; R4 is a hydrogen atom, a halogen atom, a hydroxyl group, a lower alkyl group or a group of —N(R1k)R1m; T and U are a nitrogen atom or a methine group, etc. The compounds of the invention have excellent Weel kinase-inhibitory effect and are therefore useful in the field of medicines, especially treatment of various cancers.

COMPOUNDS FOR THE TREATMENT OF DISEASES

The invention relates to compounds of formula (1) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The compounds according to the present invention are useful in

Phenylethanolamine derivatives as beta-2 agonists

The invention relates to compounds of formula (1) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The compounds according to the present invention are useful in

FORMAMIDE DERIVATIVES USEFUL AS ADRENOCEPTOR

The invention relates to compounds of formula (1) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The compounds according to the present invention are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.

COMPOUNDS HAVING BETA-AGONIST ACTIVITY

The invention relates to compounds of formula (1) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The compounds according to the present invention are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.

Sulfonamide derivatives for the treatment of diseases

The invention relates to compounds of formula (1) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The compounds according to the present invention are useful in

Compounds for the treatment of diseases

The invention relates to compounds of formula (1) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. The compounds according to the present invention are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.