38160-63-3

Usage

Uses

Used in Dye Industry:
Benzoic acid, 2-amino-4-hydroxy-, is used as a key intermediate in the production of azo dyes, which are widely used in the textile, paper, and plastics industries for their vibrant colors and excellent lightfastness.
Used in Pharmaceutical Industry:
Benzoic acid, 2-amino-4-hydroxyis used as a building block in the synthesis of various pharmaceuticals, including antibiotics, anti-inflammatory drugs, and antidepressants. Its unique chemical structure allows for the development of new and effective medications.
Used in Fragrance Industry:
Benzoic acid, 2-amino-4-hydroxy-, is used as a raw material in the production of fragrances, providing unique scents and enhancing the overall aroma of perfumes, soaps, and other personal care products.
Used in Food Industry:
As a precursor to the amino acid tryptophan, Benzoic acid, 2-amino-4-hydroxy- is used in the manufacturing of various food additives and flavors, contributing to the taste and aroma of processed foods and beverages.
Used in Skincare and Cosmetic Industry:
Due to its antioxidant and anti-inflammatory properties, benzoic acid, 2-amino-4-hydroxy-, is used as an active ingredient in the formulation of skincare and cosmetic products. It helps protect the skin from oxidative stress and inflammation, promoting a healthy and youthful appearance.

InChI:InChI=1/C7H7NO3/c8-6-3-4(9)1-2-5(6)7(10)11/h1-3,9H,8H2,(H,10,11)

Upstream product

• 124-38-9 carbon dioxide 
• 610-30-0 2,4-dinitrobenzoic acid 
• 610-36-6 4-amino-2-nitrobenzoic acid 
• 74230-08-3 4-hydroxy-2-nitrobenzoic acid 

Downstream Products

• 15540-79-1 4-amino-6-hydroxyisophthalic acid 
• 85915-70-4 acide hydroxy-4 N-benzoyl anthranilique 
• 117979-55-2 2-phenyl-7-benzoyloxy-4H-3,1-benzoxazin-4-one 
• 117979-57-4 2-(2-acetyloxyphenyl)-7-(2-acetyloxybenzoyloxy)-4H-3,1-benzoxazin-4-one 
• 79055-15-5 Acetic acid 2-[(E)-2-(4-acetoxy-phenyl)-vinyl]-4-oxo-4H-benzo[d][1,3]oxazin-7-yl ester 
• 1236056-47-5 C₁₄H₁₀N₂O₂ 
• 38196-08-6 4-hydroxy-3-amino-phenylacetic acid 
• 39134-10-6 2-(2-amino-4-hydroxyphenyl)benzothiazole 
• 115610-40-7 2-(2-hydroxybenzoyl)amino-4-hydroxybenzoic acid 
• 85915-62-4 dianthalexin 
• 108605-70-5 (E)-5-hydroxy-2-[[3-(4-hydroxyphenyl)-1-oxo-2-propenyl]amino]benzoic acid 

Relevant academic research and scientific papers

Inhibitors of serine proteases, particularly HCV NS3 protease

The present invention relates to compounds, methods and pharmaceutical compositions for inhibiting proteases, particularly serine proteases, and more particularly HCV NS3 proteases. The compounds, and the compositions and methods that utilize them, can be

Regioselective Carboxylation of Phenols with Carbon Dioxide

A few novel methods were developed for the regioselective preparation of p-hydroxybenzoic acid (pHBA) and its amino derivative by means of the Kolbe-Schmitt reaction. Thus, the carboxylation of tetraalkylammonium phenoxide at 125°C under the CO2 pressure of 5.0 MPa in the presence of K2CO3 gave pHBA in a maximum yield of 56% with the regioselectivity of 97-100%. The carboxylation of potassium phenoxide (PhOK) at 230°C under the CO2 pressure of 0.5 MPa also gave pHBA regioselectively in a 39% yield, together with unaltered phenol (61%) Under such conditions, the potassium salt of salicylic acid (SA) once formed was transformed into pHBA. Heat treatment of the dipotassium salt of 13C labeled SA indicated that the transformation occurs via two pathways, i.e., the intramolecular rearrangement of the salicylate (66%) and the decarboxylation of the salicylate followed by the recarboxylation of the resulting PhOK (34%). Furthermore, the carboxylation of cesium m-aminophenoxide and 5-amino-1-naphthoxide with CO2 gave regioselectively 4-hydroxyanthranilic and 8-amino-4-hydroxy-1-naphthoic acids, respectively, in good yields. This is a simple one-pot reaction giving these industrially useful acids with good yields.