38177-30-9

Upstream product

• 124-41-4 sodium methylate 
• 3958-60-9 2-nitrophenylmethyl bromide 
• 868-85-9 Dimethyl phosphite 
• 1455-13-6 deuteromethanol 
• 538-86-3 benzyl methyl ether 
• 88-72-2 1-methyl-2-nitrobenzene 
• 612-25-9 2-Nitrobenzyl alcohol 
• 333-27-7 methyl trifluoromethanesulfonate 
• 616-38-6 carbonic acid dimethyl ester 
• 74-88-4 methyl iodide 
• 77-78-1 dimethyl sulfate 

Downstream Products

• 62723-78-8 2-methoxymethylaniline 
• 118-92-3 anthranilic acid 
• 552-89-6 2-nitro-benzaldehyde 
• 179691-34-0 2-methoxy-2-(2-nitrophenyl)ethanol 
• 5635-98-3 2-(methoxymethyl)phenol 
• 1409968-65-5 C₂₄H₂₆FN₃O₂ 
• 337906-36-2 2-(methoxymethyl)-p-phenylenediamine 
• 3958-60-9 2-nitrophenylmethyl bromide 
• 612-96-4 2-Phenylquinoline 
• 151830-34-1 methyl N-(2-methoxymethylphenyl)-carbamate 
• 122695-32-3 N'-(2-Methoxymethyl-phenyl)-N,N-dimethyl-formamidine 
• 215600-50-3 5'-O-(2-methoxy-2-(2-nitrophenyl)ethoxycarbonyl)thymidine 
• 179691-35-1 2-methoxy-2-(2-nitrophenyl)ethoxycarbonyl chloride 

Relevant academic research and scientific papers

PESTICIDAL COMPOSITIONS AND METHODS

This disclosure relates to the field of molecules having pesticidal utility against pests in phyla Nematoda, Arthropoda, and/or Mollusca, processes to produce such molecules and intermediates used in such processes, compositions containing such molecules,

Preparation method of benzyl bromide compound

The invention relates to a method for producing a benzyl bromide compound (I or II). The method has high reaction yield, high product purity, fewer produced three wastes and good environmental compatibility. The method has remarkable economic benefit, social benefit and environmental benefit. The formula is shown in the description.

COMPOUNDS AND METHODS FOR REGULATING INSULIN SECRETION

Disclosed herein are methods for inducing insulin secretion in a glucose-dependent manner and compounds for use in these methods.

A 2 - ( methoxy methyl ) phenyl -1,4-diamine preparation method

The invention relates to a method for preparing 2-(methoxyl-methyl) phenyl-1,4-diamine. The method comprises the following steps: by taking o-nitrobenzyl alcohol as a raw material, performing methylation and hydrogenation reduction reaction so as to obtai

Pyrrolidinyl phenylurea derivatives as novel CCR3 antagonists

Optimization starting with our lead compound 1 (IC50 = 4.9 nM) led to the identification of pyrrolidinyl phenylurea derivatives. Further modification toward improvement of the bioavailability provided (R)-1-(1-((6-fluoronaphthalen-2-yl)methyl)pyrrolidin-3-yl)-3-(2-(2- hydroxyethoxy)phenyl)urea 32 (IC50 = 1.7 nM), a potent and orally active CCR3 antagonist.

Carbamates and crop protection agents containing them

Carbamates of the formula I STR1 where the substituents have the following meanings: Z is methoxy, NH2, NHCH3, N(CH3)2, CH3, C2 H5, CF3 or CCl3, X and Y are

The matrix-isolation IR spectrum of the o-quinonoid intermediate in the photolysis of 2-nitrobenzyl methyl ether

Photolysis of 2-nitrobenzyl methyl ether in Ar and N2 matrices at 12 K generated an intermediate with λmax at 430 nm, and which was itself photolabile at 430-460 nm. Matrix IR spectra, as well as the UV-visible absorption, were obtai

Ozone-mediated nitration of phenylalkyl ethers, phenylacetic esters, and related compounds with nitrogen dioxide. the highest ortho substitution observed in the electrophilic nitration of arenes

By the combined action of ozonized oxygen and nitrogen dioxide (the kyodai-nitration), the title compounds were smoothly nitrated in dichloromethane at subzero degrees with hiigh ortho positional selectivity. Although the conventional nitration of phenylacetic acid and esters mainly produces m- and p-nitro derivatives, the present nitration offers a simple high-yield synthesis of o-nitro derivatives which are important as precursor in organic synthesis. The proportions of the ortho isomer in the nitration products from methyl 2-phenylethyl ether and methyl phenylacetate were 71 and 88%, respectively, the latter value being the highest ortho isomer proportion so far observed in the electrophilic aromatic nitration. The observed high ortho selectivity has been rationalized in terms of radical cation intermediate and six-membered cyclic transition state.

REACTIVITY OF THE ACIDS OF TRIVALENT PHOSPHORUS AND THEIR DERIVATIVES. PART IV. THE REACTION OF DIALKYLPHOSPHITE ANIONS WITH NITROBENZYL BROMIDES

The reaction of o-, m- and p-nitrobenzyl bromide with sodium dimethylphosphite as well as sodium diisopropylphosphite in THF and alcohols as the solvent is described.According to the constitution of the starting materials and the solvents used, the formation of the P-C bond, debromination or dimerization occurs.The principal process in o- and p-nitrobenzyl bromide and >P-O- anion systems is believed to be X-philic substitution, the dimer is formed through a secondary process via SET from the nitrobenzyl anion to nitrobenzyl bromide.Electron-transfer and proton-transfer processes in the nitrobenzyl bromide->P-O- systems are also discussed.Key words: o-, m- and p-nitrobenzyl bromides, dialkyl phosphites, Michaelis-Becker reaction, X-philic substitution, SET.

α-AMINO CARBANIONS. A SECOND GENERATION FORMAMIDINE FOR FACILE DEPROTONATION LEADING TO α-QUATERNARY SUBSTITUTION

Formamidines derived from o-methoxymethylaniline (MMA) allow proton removal of tertiary protons in 1-substituted-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolines.