383-28-8

Usage

Uses

Used in Organic Synthesis:
1-Bromo-4-((4-fluorophenyl)sulfonyl)benzene is used as a building block in organic synthesis for the creation of complex molecules. Its unique structure allows for various chemical reactions, facilitating the synthesis of a wide range of organic compounds.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 1-Bromo-4-((4-fluorophenyl)sulfonyl)benzene is utilized as a key intermediate in the development of new pharmaceuticals. Its versatile chemical properties enable the design and synthesis of novel drug candidates with potential therapeutic applications.
Used in Pharmaceutical Development:
1-Bromo-4-((4-fluorophenyl)sulfonyl)benzene is employed as a starting material in the synthesis of pharmaceuticals. Its unique structure and reactivity contribute to the discovery of new drugs with improved efficacy and safety profiles.
Used in Agrochemicals:
1-BroMo-4-((4-fluorophenyl)sulfonyl)benzene also has potential applications in the agrochemical industry, where it can be used as a precursor for the development of new pesticides or other agrochemical products. Its chemical properties may contribute to the creation of more effective and environmentally friendly solutions for agricultural challenges.

Upstream product

• 108-86-1 bromobenzene 
• 349-88-2 4-Fluorobenzenesulfonyl chloride 
• 462-06-6 fluorobenzene 
• 824-80-6 sodium 4-fluorobenzenesulfinate 
• 106-40-1 4-bromo-aniline 
• 98-58-8 4-bromobenzenesulfonyl chloride 
• 30427-78-2 (4-bromophenyl)(4-fluorophenyl)sulfane 
• 352-34-1 4-fluoro-1-iodobenzene 
• 106-53-6 para-bromobenzenethiol 

Downstream Products

• 312-28-7 (4-bromo-3-nitro-phenyl)-(4-fluoro-3-nitro-phenyl)-sulfone 

Relevant academic research and scientific papers

Stimuli-responsive cyclometalated platinum complex bearing bent molecular geometry for highly efficient solution-processable OLEDs

Smart materials, such as stimuli-responsive luminescence, have attracted much attentions due to their potential application in semiconductor filed. In this context, platinum complexes of (dfppy-DC)Pt(acac) and (dfppy-O-DC)Pt(acac) were prepared and charac

Visible-light-driven electron donor-acceptor complex induced sulfonylation of diazonium salts with sulfinates

This work reports an efficient sulfonylation reaction enabled by a visible-light-induced radical coupling reaction between phenyl/heterocyclic diazonium salts and sulfinates. Mechanistic experiments disclosed the formation of a versatile electron donor-acceptor (EDA) complex. This transformation is characterized by an easy operational procedure under mild conditions which avoids transition metals, ligands, catalysts, and oxidants.

Synthesis method and application of diphenyl sulfone-based double-chromophore thermally activated delayed fluorescent materials

The invention discloses thermally activated delayed fluorescent materials containing double chromophores, and an application thereof in solution-processible organic electroluminescent devices. A carbazole-diphenyl sulfone blue light-emitting chromophore used as a terminal group and a triphenylamine-anthraquinone orange red light-emitting chromophore used as a central core are connected in non-conjugated and conjugated manners to construct the double-chromophore thermally activated delayed fluorescent materials. The materials are beneficial for separating the spatial distribution of the highestoccupied orbits and the lowest empty orbits of molecules to obtain a small energy gap between a single state and a triple state; and the intramolecular energy transfer of the materials changes with the connection mode, and dual emission of the single molecules is achieved. The double-chromophore thermally activated delayed fluorescent materials can be used as the luminescent layer material of a solution-processible organic electroluminescent diode to make the devices have a maximum external quantum efficiency of 3.96%.

Organic monomolecular white light material, preparation method thereof and OLED device

The invention provides an organic monomolecular white light material, a preparation method of the organic monomolecular white light material and an OLED device. The organic monomolecular white light material disclosed by the invention has room temperature phosphorescence emission properties in a solid state, and can capture triplet excitons to achieve high-efficiency light emission, and the organic monomolecular white light material also has higher thermal decomposition temperature and glass transition temperature, is simple in synthesis method and purification process, mild in reaction conditions and high in yield, and can regulate the thermal properties, luminous efficiency, white color purity and the like of a final product through connecting different aromatic fused ring groups or aromatic heterocyclic groups. The OLED device disclosed by the invention uses the organic monomolecular white light material as a light-emitting layer, and the light-emitting layer of the organic monomolecular white light material is high in brightness and good in stability, so that both the luminous efficiency and the service life of the OLED device can meet practical requirements.

Organic white light material with thermal activation delay and aggregation-induced emission performance and synthetic method and application thereof

The invention provides an organic white light material with the terminal activation delay and aggregation-induced emission performance and a synthetic method and application thereof. The general molecular formula of the white light material is Ar-Ar1-Ar2, wherein Ar is a phenothiazine electron-donating substituent group, Ar1 is a strong electron-withdrawing group, and Ar2 is an aromatic fused ring or heterocyclic aromatic substituent group except phenothiazine. The synthetic method of the material is simple, the thermal performance, luminous efficiency and white light color purity of an end product can be adjusted through connection of different aromatic fused ring or heterocyclic aromatic groups, the white light material has the thermal activation delay and aggregation-induced emission properties, the glass transition temperature is high, and the emission performance is excellent. The obtained white light material is a light emitting layer applied to preparing a non-doped OLED device, the illumination brightness is high, the stability is good, and the practicability requirement can be met.

Optimized trade-offs between triplet emission and transparency in Pt(II) acetylides through phenylsulfonyl units for achieving good optical power limiting performance

Three Pt(ii) acetylides have been prepared by coupling trans-[PtCl2(PBu3)2] to ethynyl aromatic ligands with electron-withdrawing phenylsulfonyl units in high yields (>85%). The investigation of their photophysical behavior has shown that the unique conjugation-breaking configuration of the -SO2- linker in the phenylsulfonyl units can afford a very short cut-off wavelength (λcut-off) of P) of the prepared Pt(ii) acetylides can be effectively enhanced from 0.52% to 15.92% through increasing the number of fluorine substituents on the phenylsulfonyl units in the organic ligands. Benefiting from their enhanced ΦP, the phenylsulfonyl-based Pt(ii) acetylides can exhibit comparable or even better optical power limiting (OPL) performance against 532 nm lasers than the state-of-the-art OPL material C60, indicating their great potential in the field of laser protection. All of these results have provided a new strategy to achieve consistency between high OPL ability and good transparency for OPL materials, representing a valuable attempt for coping with key problems in the field of nonlinear optics.

The synthesis of diarylsulfones with simple arenes and K2S2O8 through double C-S bond formation

An unprecedented double C-S bond formation method has been developed to prepare both symmetric and unsymmetric diarylsulfones with simple arenes in a single step. This represents the first example that K2S2O8 can be employed as a highly effective sulfonating agent to synthesize diarylsulfones. The reaction demonstrates excellent reactivity, good functional group tolerance and high yields.

BIPHENYLOXYACETIC ACID DERIVATIVES FOR THE TREATMENT OF RESPIRATORY DISEASE

The invention relates to substituted phenoxyacetic acids as useful pharmaceutical compounds for treating respiratory disorders, pharmaceutical compositions containing them, and processes for their preparation.

Indium(III)-catalysed aryl sulfonylation reactions

A rapid, high yielding and regioselective process has been developed for the synthesis of biaryl sulfones via sulfonylation reactions catalysed by indium(III) chloride.

Preparation process of fluorine substituted aromatic compound

A preparation process of a fluorine substituted aromatic compound comprising reacting an alkali metal or alkali earth metal salt of an aromatic compound having a hydroxy group with an organic fluorinating agent is disclosed. As a representative fluorinating agent, a bis-dialkylamino-difluoromethane compound, for example, 2,2′-difluoro-1,3-dimethylimidazolidine, is exemplified. According to the process, an industrially useful fluorinated aromatic compound, for example, a fluorobenzene, a fluorine substituted benzophenone, a fluorine substituted diarylsulfone can be prepared with ease in economy without specific equipment.