6228-40-6Relevant academic research and scientific papers
Online Monitoring of Methanol Electro-Oxidation Reactions by Ambient Mass Spectrometry
Cheng, Si,Wu, Qiuhua,Dewald, Howard D.,Chen, Hao
, p. 1005 - 1012 (2017)
Online detection of methanol electro-oxidation reaction products [e.g., formaldehyde (HCHO)] by mass spectrometry (MS) is challenging, owing to the high salt content and extreme pH of the electrolyte solution as well as the difficulty in ionizing the reac
Shaken, not stirred: a schools test for aldehydes and ketones
Plater, M John
, p. 104 - 107 (2019/11/22)
A schools test for aldehydes and ketones in water at room temperature using test tubes has been developed in this laboratory using either phenylhydrazine hydrochloride or phenylhydrazine hydrochloride with NaOAc . 3H2O. The role of one equivalent of a strong or weak acid which catalyses the reaction is discussed.
Selective Conversion of Carbon Dioxide to Formaldehyde via a Bis(silyl)acetal: Incorporation of Isotopically Labeled C1 Moieties Derived from Carbon Dioxide into Organic Molecules
Rauch, Michael,Strater, Zack,Parkin, Gerard
supporting information, p. 17754 - 17762 (2019/11/05)
The conversion of carbon dioxide to formaldehyde is a transformation that is of considerable significance in view of the fact that formaldehyde is a widely used chemical, but this conversion is challenging because CO2 is resistant to chemical transformations. Therefore, we report here that formaldehyde can be readily obtained from CO2 at room temperature via the bis(silyl)acetal, H2C(OSiPh3)2. Specifically, formaldehyde is released from H2C(OSiPh3)2 upon treatment with CsF at room temperature. H2C(OSiPh3)2 thus serves as a formaldehyde surrogate and provides a means to incorporate CHx (x = 1 or 2) moieties into organic molecules. Isotopologues of H2C(OSiPh3)2 may also be synthesized, thereby providing a convenient means to use CO2 as a source of isotopic labels in organic molecules.
A Multicomponent Electrosynthesis of 1,5-Disubstituted and 1-Aryl 1,2,4-Triazoles
Yang, Na,Yuan, Gaoqing
, p. 11963 - 11969 (2018/09/25)
A novel electrochemical route has been developed for the synthesis of 1,5-disubstituted and 1-aryl 1,2,4-triazoles from aryl hydrazines, paraformaldehyde, NH4OAc, and alcohols. In this multicomponent reaction system, alcohols act as solvents as well as reactants and NH4OAc is used as the nitrogen source. With the assistance of reactive iodide radical or I2 and NH3 electrogenerated in situ, this process could effectively avoid the use of strong oxidants and transition-metal catalysts and be smoothly carried out at room temperature to give a wide array of 1,2,4-triazole derivatives in good to high yields. Preliminary studies reveal that the reaction mechanism involves a radical process.
A novel electrochemical conversion of CO2 with aryl hydrazines and paraformaldehyde into 1,3,4-oxadiazol-2(3H)-one derivatives in one step
Yang, Na,Lai, Qiang,Jiang, Huanfeng,Yuan, Gaoqing
, p. 109 - 112 (2016/09/28)
Using CO2 to replace phosgene or CO as the C1 synthon, we successfully achieved the one-pot electrochemical synthesis of 1,3,4-oxadiazol-2(3H)-one derivatives via a three-component coupling reaction of CO2 with aryl hydrazines and pa
Reactions of arenediazonium o-benzenedisulfonimides with aliphatic triorganoindium compounds
Barbero, Margherita,Cadamuro, Silvano,Dughera, Stefano,Ghigo, Giovanni
scheme or table, p. 862 - 868 (2009/04/11)
The reaction of various arenediazonium o-benzenedisulfonimides with aliphatic triorganoindium compounds is described. Surprisingly, with triethyl- or tributylindium we obtained N-ethyl- or N-butylanilines, respectively. This is the first case in which, at least formally, the reactive site of a diazonium salt is the nitrogen atom directly bonded to the aromatic ring. In contrast, with trimethylindium we obtained only formaldehyde (aryl)hydrazones. In order to explain the difference between trimethyl- and triethylindium we have proposed some reaction mechanisms, supported by detailed density functional (DFT) calculations. The possible role of diazene/hydrazone tautomerism initially assumed was discarded and therefore three mechanisms for the key step (nucleophilic addition of the trialkylindium to the N=N double bond of diazene) were studied. For the favoured mechanism there is a difference in the energy barriers of 2 kcalmol-1 between the reactions with trimethyl- and triethylindium. This difference is explained on the basis of the different C-In bond energies in the two organometallics and it is assumed to be enough to explain their different behaviour under the experimental conditions. Wiley-VCH Verlag GmbH & Co. KGaA, 2008.
Cyclothiomethylation of aryl hydrazines with formaldehyde and hydrogen sulfide
Akhmetova,Nadyrgulova,Tyumkina,Starikova,Golovanov,Antipin,Kunakova,Dzhemilev
, p. 1824 - 1834 (2007/10/03)
Cyclothiomethylation of phenyl hydrazine with CH2O and H 2S in a ratio of 1: 3: 2 in an acidic medium (HCl) afforded previously unknown 3-phenyl-1,3,4-thiadiazolidine (35% yield) and N-phenyl(perhydro-1,3,5-dithiazin-5-yl)amine (35%
Gold(I)-catalyzed oxidative cleavage of a C-C double bond in water
Xing, Dong,Guan, Bingtao,Cai, Guixin,Fang, Zhao,Yang, Liping,Shi, Zhangjie
, p. 693 - 696 (2007/10/03)
Oxidative cleavage of the C=C bond to afford ketone or aldehyde products with tert-butyl hydrogenperoxide (TBHP) as the oxidant can be catalyzed by AuCl with neocuproine (1) in water.
Investigations on the stability of l-methyl-2-phenylacetohydrazide
Bresser,Weber
, p. 470 - 476 (2007/10/03)
l-Methyl-2-phenylacetohydrazide (1), a degradation product of dipyrone, is hydrolytically stable. In contrast it is oxidized into several products like 3a/3b, 4 and 5a/5b. The composition of the reaction mixture depends on the oxidation conditions (ferricyanide; hydrogenperoxide with/without peroxidase; pH 5-9) and was determined by capillary column gaschromatography.
