38940-44-2

Basic information

• Product Name: 7-oxo-6,7-diphenylheptanenitrile
• Synonyms: 7-oxo-6,7-diphenylheptanenitrile
• CAS NO: 38940-44-2
• Molecular Weight: 277.366
• Mol File: 38940-44-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 7-oxo-6,7-diphenylheptanenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 7-oxo-6,7-diphenylheptanenitrile(38940-44-2)
• EPA Substance Registry System: 7-oxo-6,7-diphenylheptanenitrile(38940-44-2)

Safety Data

• Hazardous Substances Data: 38940-44-2(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 4452-11-3 1,2-diphenylprop-2-en-1-one 
• 2972-05-6 cyclobutanone oxime 
• 38940-42-0 6-Chloro-1,2-diphenyl-hexan-1-one 
• 143-33-9 sodium cyanide 
• 100-42-5 styrene 
• 451-40-1 phenyl benzyl ketone 

Relevant articles and documents

Organocatalytic Three-Component 1,2-Cyanoalkylacylation of Alkenes via Radical Relay

Here, we report an unprecedented regioselective, intermolecular 1,2-cyanoalkylacylation of feedstock alkenes with readily available oxime esters and aldehydes by N-heterocyclic carbene (NHC) organocatalysis. The crux of this success is the exquisite control over the radical relay process by an NHC organocatalyst. This protocol offers a general platform for diversity-oriented synthesis of valuable ketonitriles under mild, transition-metal-free, and redox-neutral conditions and highlights its potential in the late-stage functionalization of pharmaceutical architectures and natural products.

Photocatalytic, Phosphoranyl Radical-Mediated N-O Cleavage of Strained Cycloketone Oximes

A photoinduced, phosphoranyl radical-mediated protocol for the direct N-O cleavage of strained cycloketone oximes via a polar/SET crossover process was developed for the first time. This visible-light-driven direct N-O activation mode for oxime offers beneficial features such as streamlined synthetic process and versatile photochemical reactivities. Consequently, the alkenes and α-trifluoromethyl alkenes with varied electronic and structural features acted as competent radical receptors in this protocol, enabling facile accesses to a range of elongated cyano and/or gem-difluoroalkene-bearing compounds.