39076-18-1

Basic information

• Product Name: N-(3-Methylphenyl)carbamic acid methyl ester
• Synonyms: N-(3-Methylphenyl)carbamic acid methyl ester
• CAS NO: 39076-18-1
• Molecular Formula: C₉H₁₁NO₂
• Molecular Weight: 165.1891
• Mol File: 39076-18-1.mol
• Article Data: 16

Chemical Properties

• Boiling Point: 206.8°Cat760mmHg
• Flash Point: 78.9°C
• Appearance: /
• Density: 1.138g/cm³
• Vapor Pressure: 0.232mmHg at 25°C
• Refractive Index: 1.562
• CAS DataBase Reference: N-(3-Methylphenyl)carbamic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3-Methylphenyl)carbamic acid methyl ester(39076-18-1)
• EPA Substance Registry System: N-(3-Methylphenyl)carbamic acid methyl ester(39076-18-1)

Safety Data

• Hazardous Substances Data: 39076-18-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H11NO2/c1-7-4-3-5-8(6-7)10-9(11)12-2/h3-6H,1-2H3,(H,10,11)

Upstream product

• 67-56-1 methanol 
• 201230-82-2 carbon monoxide 
• 108-44-1 1-amino-3-methylbenzene 
• 6294-89-9 hydrazinecarboxylic acid methyl ester 
• 616-38-6 carbonic acid dimethyl ester 
• 124-38-9 carbon dioxide 
• 590-28-3 potassium cyanate 
• 591-17-3 meta-bromotoluene 
• 618-47-3 m-toluamide 
• 621-29-4 3-tolyl isocyanate 
• 17933-03-8 m-tolylboronic acid 
• 79-22-1 methyl chloroformate 
• 289909-33-7 4-m-tolyl-1,2,4-triazoline-3,5-dione 
• 149-73-5 trimethyl orthoformate 

Downstream Products

• 39074-44-7 Chloromethyl-m-tolyl-carbamic acid methyl ester 

Relevant articles and documents

Copper-Catalyzed Coupling of Amines with Carbazates: An Approach to Carbamates

A new approach for the preparation of carbamatesviathe copper-catalyzed cross-coupling reaction of amines with alkoxycarbonyl radicals generated from carbazates is described. This environmentally friendly protocol takes place under mild conditions and is compatible with a wide range of amines, including aromatic/aliphatic and primary/secondary substrates.

Electrochemical Hofmann rearrangement mediated by NaBr: Practical access to bioactive carbamates

An electrochemical Hofmann rearrangement is reported. With the mediation of NaBr, highly corrosive and toxic halogens are avoided. Moreover, this efficient and green approach is well compatible with a broad range of amides, including several commercial medicine derivatives, and provides direct access to synthetically useful carbamates. The synthetic utility of this method is also demonstrated by the preparation of 15N labeling carbamate and gram-scale synthesis of Amantadine.

A PROCESS FOR THE SYNTHESIS OF AROMATIC CARBAMATES

The present invention discloses a process for the synthesis of aromatic carbamates from amine with dialkyl carbonate in the presence of binary or ternary mixed metal oxide catalyst. The present invention further discloses the yield of said aromatic carbamate in the range of 60 to 99%. Further, the ratio of amine to dialkyl carbonate is in the range of 1:2 to 1:30.