41295-20-9

Basic information

• Product Name: 4-AMINO-4'-METHYLDIPHENYL ETHER
• Synonyms: AKOS B033070;AKOS BBS-00006937;AKOS BC-0768;4-(P-TOLYLOXY)BENZENAMINE;4-(P-TOLYLOXY)ANILINE;4-AMINO-4'-METHYLDIPHENYL ETHER;4-AMINOPHENYL P-TOLYL ETHER;4-(4-METHYLPHENOXY)ANILINE
• CAS NO: 41295-20-9
• Molecular Formula: C₁₃H₁₃NO
• Molecular Weight: 199.25
• EINECS: 255-298-7
• Product Categories: Amines;Phenyls & Phenyl-Het;Phenyls & Phenyl-Het
• Mol File: 41295-20-9.mol
• Article Data: 15

Chemical Properties

• Melting Point: 122°C
• Boiling Point: 333.1 °C at 760 mmHg
• Flash Point: 160.4 °C
• Appearance: /
• Density: 1.115 g/cm³
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: 4.86±0.10(Predicted)
• CAS DataBase Reference: 4-AMINO-4'-METHYLDIPHENYL ETHER(CAS DataBase Reference)
• NIST Chemistry Reference: 4-AMINO-4'-METHYLDIPHENYL ETHER(41295-20-9)
• EPA Substance Registry System: 4-AMINO-4'-METHYLDIPHENYL ETHER(41295-20-9)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 36/37/38-22
• Safety Statements: 26-36/37/39
• HazardClass: IRRITANT
• Hazardous Substances Data: 41295-20-9(Hazardous Substances Data)

Usage

General Description

4-Amino-4'-Methyldiphenyl Ether, also known as 4,4'-Dimethoxydiphenylamine, is a chemical compound with the formula C14H15NO2. It is a pale yellow solid that is commonly used as an intermediate in the production of dyes, pigments, and pharmaceuticals. It is also used as a stabilizer for certain polymers and as an antioxidant for rubber products. The chemical is classified as a primary aromatic amine and requires proper handling and storage to prevent potential health hazards. Additionally, it is considered a hazardous substance and should be handled with care to avoid harmful effects on human health and the environment.

Upstream product

• 3402-74-2 4-(4-nitrophenoxy)toluene 
• 352-32-9 p-fluorotoluene 
• 123-30-8 4-amino-phenol 
• 106-44-5 p-cresol 
• 371-40-4 4-fluoroaniline 
• 100-00-5 4-chlorobenzonitrile 
• 1192-96-7 potassium p-cresolate 
• 586-78-7 para-nitrophenyl bromide 
• 106-38-7 para-bromotoluene 
• 624-31-7 4-tolyl iodide 
• 122-18-9 cetyldimethylbenzylammonium chloride 
• 106-47-8 4-chloro-aniline 
• 106-40-1 4-bromo-aniline 
• 350-46-9 4-Fluoronitrobenzene 

Downstream Products

• 331974-00-6 N-(4-(p-tolyloxy)phenyl)acetamide 
• 92556-18-8 1-(4-p-tolyloxy-phenyl)-biguanide 
• 109125-90-8 (4-p-tolyloxy-phenyl)-guanidine 
• 1706-12-3 4-phenoxytoluene 
• 6377-63-5 4-chlorophenyl 4-methylphenyl ether 
• 56884-87-8 2-phenyl-3-(4-p-tolyloxy-phenyl)-thiazolidin-4-one 
• 56884-92-5 2-(4-methoxy-phenyl)-3-(4-p-tolyloxy-phenyl)-thiazolidin-4-one 
• 73944-71-5 Benzotriazol-1-ylmethyl-(4-p-tolyloxy-phenyl)-amine 
• 73944-61-3 (2-Methyl-benzoimidazol-1-ylmethyl)-(4-p-tolyloxy-phenyl)-amine 
• 73944-73-7 2-[(4-p-Tolyloxy-phenylamino)-methyl]-isoindole-1,3-dione 
• 73944-79-3 3-[(4-p-Tolyloxy-phenylamino)-methyl]-3H-benzooxazole-2-thione 
• 73944-69-1 3-[(4-p-Tolyloxy-phenylamino)-methyl]-3H-benzothiazole-2-thione 
• 73944-66-8 6-Nitro-3-[(4-p-tolyloxy-phenylamino)-methyl]-3H-benzooxazol-2-one 
• 94549-19-6 4'-(4-Methyl-phenoxy)-4-methyl-diphenylthioaether 

Relevant articles and documents

Oxalohydrazide Ligands for Copper-Catalyzed C?O Coupling Reactions with High Turnover Numbers

Here, we report a class of ligands based on oxalohydrazide cores and N-amino pyrrole and N-amino indole units that generates long-lived copper catalysts for couplings that form the C?O bonds in biaryl ethers. These Cu-catalyzed coupling of phenols with aryl bromides occurred with turnovers up to 8000, a value which is nearly two orders of magnitude higher than those of prior couplings to form biaryl ethers and nearly an order of magnitude higher than those of any prior copper-catalyzed coupling of aryl bromides and chlorides. This ligand also led to copper systems that catalyze the coupling of aryl chlorides with phenols and the coupling of aryl bromides and iodides with primary benzylic and aliphatic alcohols. A wide variety of functional groups including nitriles, halides, ethers, ketones, amines, esters, amides, vinylarenes, alcohols and boronic acid esters were tolerated, and reactions occurred with aryl bromides in pharmaceutically related structures.

CoII Immobilized on Aminated Magnetic-Based Metal–Organic Framework: An Efficient Heterogeneous Nanostructured Catalyst for the C–O Cross-Coupling Reaction in Solvent-Free Conditions

Abstract: In this paper, we report the synthesis of Fe3O4?AMCA-MIL53(Al)-NH2-CoII NPs based on the metal–organic framework structures as a magnetically separable and environmentally friendly heterogeneous nanocatalyst. The prepared nanostructured catalyst efficiently promotes the C–O cross-coupling reaction in solvent-free conditions without the need for using toxic solvents and/or expensive palladium catalyst. Graphic Abstract: [Figure not available: see fulltext.].

Method for preparing aminodiphenyl ether by p-nitrchlorobenzene serving as raw material

The invention relates to a preparation method of aminodiphenyl ether, in particular to a method for preparing aminodiphenyl ether by p-nitrchlorobenzene serving as a raw material. The method includesthe steps: etherification reaction; oil-water phase separation of etherification products; catalytic hydrogenation reaction; filtering; rectification and the like. The method for preparing the aminodiphenyl ether by the p-nitrchlorobenzene serving as the raw material is clean, environmentally friendly, simple to operate, low in energy consumption and pollution-free in environment, and the aminodiphenyl ether prepared by the method is high in yield and purity. According to the method for preparing the aminodiphenyl ether by the p-nitrchlorobenzene serving as the raw material, phase transfer catalysts are less in dosage, and fewer by-products are generated in the reaction process.