41388-50-5

Basic information

• Product Name: 1-(allyloxy)-3-bromobenzene
• Synonyms: 1-(allyloxy)-3-bromobenzene
• CAS NO: 41388-50-5
• Molecular Formula: C₉H₉BrO
• Molecular Weight: 213.07116
• Mol File: 41388-50-5.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 246°Cat760mmHg
• Flash Point: 108.9°C
• Appearance: /
• Density: 1.35g/cm³
• Vapor Pressure: 0.0435mmHg at 25°C
• Refractive Index: 1.541
• CAS DataBase Reference: 1-(allyloxy)-3-bromobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(allyloxy)-3-bromobenzene(41388-50-5)
• EPA Substance Registry System: 1-(allyloxy)-3-bromobenzene(41388-50-5)

Safety Data

• Hazardous Substances Data: 41388-50-5(Hazardous Substances Data)

Usage

General Description

1-(allyloxy)-3-bromobenzene is an organic compound with the chemical formula C9H9BrO. It is a benzene derivative with a bromine atom at position 3 and an allyloxy group at position 1. 1-(allyloxy)-3-bromobenzene is commonly used in organic synthesis as a starting material for the preparation of various types of organic molecules. It is also utilized in the production of pharmaceuticals, agrochemicals, and other fine chemicals. Additionally, 1-(allyloxy)-3-bromobenzene is a useful reagent in transition metal-catalyzed cross-coupling reactions, allowing for the formation of carbon-carbon bonds in organic synthesis. Overall, this chemical compound has important applications in the field of organic chemistry.

InChI:InChI=1/C9H9BrO/c1-2-6-11-9-5-3-4-8(10)7-9/h2-5,7H,1,6H2

Upstream product

• 760980-83-4 (Z)-1-bromo-3-(prop-1-en-1-yloxy)benzene 
• 591-20-8 3-Bromophenol 
• 556-56-9 allyl iodid 
• 106-95-6 allyl bromide 

Downstream Products

• 1446-24-8 3-allylphenol 
• 108-95-2 phenol 
• 760980-83-4 (Z)-1-bromo-3-(prop-1-en-1-yloxy)benzene 
• 591-20-8 3-Bromophenol 
• 13849-32-6 3,4-dihydro-5-hydroxy-2H-1-benzopyran 
• 319478-14-3 5-bromochromane 
• 1179810-92-4 1-hydroxy-1-(3-(propen-3-yl)oxyphenyl)-1,2-dihydropyrrolo[3,4-c]pyridine-3-one 

Relevant articles and documents

Nickel Hydride Catalyzed Cleavage of Allyl Ethers Induced by Isomerization

This report discloses the deallylation of O - and N -allyl functional groups by using a combination of a Ni-H precatalyst and excess Bronsted acid. Key steps are the isomerization of the O - or N -allyl group through Ni-catalyzed double-bond migration followed by Bronsted acid induced O/N-C bond hydrolysis. A variety of functional groups are tolerated in this protocol, highlighting its synthetic value.

ARYLPIPERAZINES

The present invention relates to arylpiperazines, and to the efficient treatment of an individual afflicted with L-DOPA-induced dyskinesia, which condition typically arises as a consequence of long-term treatment with L-DOPA therapy in Parkinson patients,

Development of isoniazid-NAD truncated adducts embedding a lipophilic fragment as potential bi-substrate InhA inhibitors and antimycobacterial agents

Isoniazid-NAD truncated adducts embedding a lipophilic fragment were designed, synthesized and evaluated as inhibitors of the enoyl-acyl carrier protein (ACP) reductase (InhA) of Mycobacterium tuberculosis and as antimycobacterial agents. These compounds, planned as bi-substrate inhibitors and inspired from the active metabolite of isoniazid, combine both the nicotinamide moiety of the cofactor NAD and a lipophilic hydrocarbon chain mimic of the InhA substrate. The lipophilic fragment was introduced using either Suzuki-Miyaura cross-coupling or a classical nucleophilic substitution reaction. Several compounds developed in this work were indeed able to inhibit the InhA activity and showed promising antimycobacterial activities. However a direct correlation between the expressed activity and the bi-substrate mode of action could not yet be unambiguously demonstrated.