41882-23-9

Upstream product

• 141-52-6 sodium ethanolate 
• 130117-94-1 N¹-(p-chlorobenzoyl)-N¹-(p-methylbenzyl)-N²-(p-nitrophenyl)-formamidine 
• 450408-66-9 4,5-dichloro-2-(4-chloro-benzoyl)-2H-pyridazin-3-one 
• 104-84-7 para-methylbenzylamine 
• 623-03-0 4-Cyanochlorobenzene 
• 589-18-4 4-Methylbenzyl alcohol 
• 1228693-30-8 C₂₆H₁₉ClF₁₇NO₂ 
• 619-56-7 4-chlorobenzamide 
• 122-01-0 4-chloro-benzoyl chloride 

Downstream Products

• 39193-07-2 N-(4-nitrophenyl)-4-chlorophenyl carboxamide 
• 130117-94-1 N¹-(p-chlorobenzoyl)-N¹-(p-methylbenzyl)-N²-(p-nitrophenyl)-formamidine 
• 130340-58-8 N,N-bis(p-nitrophenyliminomethyl)-p-nitroaniline 
• 74-11-3 para-chlorobenzoic acid 

Relevant academic research and scientific papers

H-β-zeolite catalyzed transamidation of carboxamides, phthalimide, formamides and thioamides with amines under neat conditions

Efficient transamidation of unactivated carboxamides, phthalimides, formamides and thioamides with amines under solvent-free conditions using H-β-zeolite as a green and recyclable heterogeneous catalyst is described. Easy work up, high purity of the products, recyclability and environmentally-friendly nature of the catalyst are the attractive features of the present methodology. This is the first report for the transamidation of thioamides under heterogeneous conditions.

Synthesis and application of a new fluorous-tagged ammonia equivalent

A novel fluorous-tagged ammonia equivalent has been developed. It is based on a nitrogen-oxygen bond, which can be cleaved in a traceless manner by a molybdenum complex or samarium diiodide. The application in the synthesis of ureas, amides, sulfonamides, and carbamates is described. The scope of the fluo-rous N-O linker is exemplified by the synthesis of itopride, a drug used for the treatment of functional dyspepsia. Itopride was synthesized with the aid of fluorous purification methods and the product was isolated in good overall yield, with high purity.

Nafion-catalyzed microwave-assisted Ritter reaction: an atom-economic solvent-free synthesis of amides

An atom-economic solvent-free synthesis of amides by the Ritter reaction of alcohols and nitriles under microwave irradiation is reported. This green protocol is catalyzed by solid-supported NafionNR50 with improved efficiency and reduced waste production.

2-Acylpyridazin-3-ones: Novel mild and chemoselective acylating agents for amines

2-Acyl-4,5-dichloropyridazin-3-ones served as excellent novel N-acylating reagents for amines under neutral conditions in organic solvent. They are convenient, chemoselective and easy to handle stable N-acylating reagents of amines.