42164-79-4

Usage

Uses

Used in Organic Synthesis:
α-Hydroxy-3-nitrobenzeneacetic acid is used as a key intermediate in the synthesis of various organic compounds due to its reactive functional groups. It serves as a versatile building block for the preparation of a wide range of chemical products.
Used in Pharmaceutical Industry:
α-Hydroxy-3-nitrobenzeneacetic acid is used as a starting material for the synthesis of various pharmaceuticals. Its functional groups allow for the development of new drug candidates with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical industry, α-Hydroxy-3-nitrobenzeneacetic acid is utilized as a precursor for the synthesis of agrochemicals, such as pesticides and herbicides. Its reactivity enables the creation of effective compounds for crop protection and management.
Used in Materials Science:
α-Hydroxy-3-nitrobenzeneacetic acid has potential applications in the field of materials science. It can be used as a starting material for the synthesis of various specialty chemicals, contributing to the development of new materials with unique properties and applications.

InChI:InChI=1/C8H7NO5/c10-7(8(11)12)5-2-1-3-6(4-5)9(13)14/h1-4,7,10H,(H,11,12)

Upstream product

• 13312-88-4 meta nitromandelic acid ethyl ester 
• 7664-93-9 sulfuric acid 
• 30077-08-8 d-α-amino-m-nitrophenylacetic acid 
• 7647-01-0 hydrogenchloride 
• 93555-01-2 2-(3-nitrophenyl)-2-[(trimethylsilyl)oxy]acetonitrile 
• 2227-64-7 3'-nitro-2-bromoacetophenone 
• 2835-06-5 phenylglycin 
• 99-61-6 3-nitro-benzaldehyde 
• 7677-24-9 trimethylsilyl cyanide 
• 6890-77-3 3-nitrophenylglyoxal 
• 151-50-8 potassium cyanide 
• 13312-82-8 3-nitro-mandelonitrile 
• 13651-07-5 2,2-dibromo-1-(3-nitrophenyl)ethan-1-one 

Downstream Products

• 75172-64-4 (R)-(-)-3-nitromandelic acid 
• 602301-53-1 (S)-Acetoxy-(3-nitro-phenyl)-acetic acid 
• 5496-38-8 2-(3-nitrophenyl)-4,5-diphenyl-1H-imidazole 
• 1173294-94-4 (3-nitrophenyl)(2-(pyridin-2-yl)phenyl)methanone 
• 17430-90-9 (RS)-methoxy-(3-nitro-phenyl)-acetic acid methyl ester 
• 97522-72-0 anhydro-2-(3-acetamidophenyl)-3-hydroxythiazolo<3,2-a>pyridinium hydroxide 
• 97522-70-8 anhydro-2-(3-aminophenyl)-3-hydroxythiazolo<3,2-a>pyridinium hydroxide 
• 75172-60-0 (S)-(+)-3-nitromandelic acid 
• 99-61-6 3-nitro-benzaldehyde 
• 6330-40-1 2-(3-nitrophenyl)-2-oxoacetic acid 
• 97522-68-4 anhydro-2-(3-nitrophenyl)-3-hydroxythiazolo<3,2-a>pyridinium hydroxide 
• 92057-09-5 ethyl 2-(3-nitrophenyl)-2-oxoacetate 
• 52944-27-1 (R,S)-2-hydroxy-2-(3-aminophenyl)acetic acid 

Relevant academic research and scientific papers

Enzymatic resolution of substituted mandelic acids

A series of substituted mandelic acids were prepared and subjected to enzymatic resolution utilizing Lipase PS 'Amano'.

7-α-Amino-substituted acylamino-3-(1-carboxymethyltetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acids

Certain 7-acylamido-3-(1-carboxy-loweralkyl-tetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acids and their salts and easily hydrolyzed esters of the 4-carboxyl group were synthesized and found to be potent antibacterial agents which exhibited good aqueous solubility. In a preferred embodiment the 7-substituent was 2'-aminomethylphenylacetamido.

7-(D-α-Hydroxy-2-arylacetamido)-3-(2-carboxyalkyl-2,3-dihydro-s-triazolo-[4,3-b]pyridazin-3-on-6-ylthiomethyl)-3-cephem-4-carboxylic acids and derivatives

7-(D-α-Hydroxy-2-arylacetamido)-3-(2-carboxyalkyl-2,3-dihydro-s-triazolo[4,3-b]pyridazin-3-on-6-ylthiomethyl)-3-cephem-4-carboxylic acids and derivatives containing blocking groups on the α-hydroxy group and their nontoxic, pharmaceutically acceptable salts are valuable as antibacterial agents and are particularly valuable as therapeutic agents in poultry and in animals, including man, in the treatment of infectious diseases caused by many Gram-positive and Gram-negative bacteria. A preferred compound is 7-(D-mandelamido)-3-(2-carboxyalkyl-2,3-dihydro-s-triazolo[4,3-b]pyridazin-3-on-6-ylthiomethyl)-3-cephem-4-carboxylic acid.

7-(D-α-Hydroxy-2-arylacetamido)-3-(tetrazolo-[4,5-b]pyridazin-6-ylthiomethyl)-3-cephem-4-carboxylic acids

7-(D-α-Hydroxy-2-arylacetamido)-3-(tetrazolo-[4,5-b]pyridazin-6-ylthiomethyl)-3-cephem-4-carboxylic acids and their nontoxic, pharmaceutically acceptable salts are valuable as antibacterial agents and are particularly valuable as therapeutic agents in poultry and animals, including man, in the treatment of infectious diseases caused by many Gram-positive and Gram-negative bacteria.