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2-Phenyl-1,3,4-thiadiazole is an organic compound with the chemical formula C9H6N2S. It is a heterocyclic aromatic molecule that features a thiadiazole ring, which consists of a five-membered ring with one sulfur atom and two nitrogen atoms. The phenyl group (C6H5) is attached to the thiadiazole ring at the 2-position, providing the compound with its characteristic structure. 2-phenyl-1,3,4-thiadiazole is known for its potential applications in various fields, such as pharmaceuticals and materials science, due to its unique electronic properties and chemical reactivity. It can be synthesized through various methods, including cyclization reactions involving phenyl-substituted thioamides or other precursors. The compound's properties, such as its stability and reactivity, make it a subject of interest for further research and development in the creation of new drugs, dyes, and other specialty chemicals.

4291-14-9

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4291-14-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 4291-14-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,2,9 and 1 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 4291-14:
(6*4)+(5*2)+(4*9)+(3*1)+(2*1)+(1*4)=79
79 % 10 = 9
So 4291-14-9 is a valid CAS Registry Number.

4291-14-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-phenyl-1,3,4-thiadiazole

1.2 Other means of identification

Product number -
Other names 5-phenyl-1,3,4-thiadiazole radical

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:4291-14-9 SDS

4291-14-9Relevant academic research and scientific papers

COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME

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Paragraph 0284-0287; 0292-0295, (2021/01/29)

The present specification provides a compound represented by chemical formula 1 and an organic light emitting device including the same. The compound may improve lifespan characteristics of the organic light emitting device.

Preparation of 1,3,4-oxadiazoles and 1,3,4-thiadiazoles via chemoselective сyclocondensation of electrophilically activated nitroalkanes to (thio)semicarbazides or thiohydrazides

Aksenov, Alexander V.,Aksenov, Dmitrii A.,Aksenov, Nicolai A.,Arutiunov, Nikolai A.,Kirillov, Nikita K.,Rubin, Michael

, p. 1067 - 1072 (2020/10/02)

[Figure not available: see fulltext.] Unusual reaction proceeding via the electrophilic activation of nitroalkanes in the presence of polyphosphoric acid has been discovered. Subsequent nucleophilic attack with semicarbazides or thiosemicarbazides allows

TiCl4 mediated facile synthesis of 1,3,4-oxadiazoles and 1,3,4-thiadiazoles

Zhang, Lin,Yu, Yu,Tang, Qiang,Yuan, Jianyong,Ran, Dongzhi,Tian, Binghua,Pan, Tao,Gan, Zongjie

, p. 423 - 431 (2019/12/27)

An efficient method for the synthesis of 2,5-disubstituted 1,3,4-oxadiazoles and 1,3,4-thiadiazoles has been developed. Various hydrazides or thionyl hydrazides readily react with DMA derivatives in the presence of TiCl4 as a catalyst to afford the desired products. This protocol provides a simple and economical procedure that affords the target products with good yields and wide substrate scope.

Preparation method of 1, 3, 4-thiadiazole compound and compound prepared by preparation method

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Paragraph 0019-0020; 0065-0070, (2020/12/10)

The invention belongs to the field of medicinal chemistry. Specifically, the invention discloses a preparation method of a 1, 3, 4-thiadiazole compound and the compound prepared by using the preparation method. According to the method, the 1, 3, 4-thiadia

A KHSO4 promoted tandem synthesis of 1,3,4-thiadiazoles from thiohydrazides and DMF derivatives

Gan, Zongjie,Tian, Binghua,Yuan, Jianyong,Ran, Dongzhi,Zhang, Lin,Dong, Gang,Pan, Tao,Zeng, Yixin,Yu, Yu

supporting information, (2020/07/15)

An efficient, simple and environmentally benign method for the construction of 1,3,4-thiadiazole skeletons via the tandem coupling and cyclization of thiohydrazides with DMF derivatives in the presence of KHSO4 has been reported. This method re

Transition-metal-free oxidative iodination of 1,3,4-oxadiazoles

Dannenberg, Carl Albrecht,Bizet, Vincent,Zou, Liang-Hua,Bolm, Carsten

supporting information, p. 77 - 80 (2015/02/02)

Transition-metal-free oxidative iodination of 2-substituted 1,3,4-oxadiazoles was achieved by using sodium iodide as the halide source and Selectfluor as the oxidant. Variously substituted products were obtained in moderate to good yields under operationa

Multinuclear magnetic resonance studies of 2-aryl-1,3,4-thiadiazoles

Gierczyk, B?azej,Ceg?owski, Micha?,Ka?mierczak, Marcin,Zalas, MacIej

, p. 637 - 641 (2012/10/29)

The 1H, 13C and 15N spectra of aryl-substituted 1,3,4-thiadiazoles were recorded. The results obtained were correlated with Hammett coefficients. The experimental results were compared with DFT-calculated chemical shifts.

Greener and rapid access to bio-active heterocycles: one-pot solvent-free synthesis of 1,3,4-oxadiazoles and 1,3,4-thiadiazoles

Polshettiwar, Vivek,Varma, Rajender S.

, p. 879 - 883 (2008/09/17)

A novel one-pot solvent-free synthesis of 1,3,4-oxadiazoles and 1,3,4-thiadiazoles by condensation of acid hydrazide and triethyl orthoalkanates under microwave irradiations is reported. This green protocol was catalyzed efficiently by solid supported NafionNR50 and phosphorus pentasulfide in alumina (P4S10/Al2O3) with excellent yields.

SEMICARBAZONES AND THIOSEMICARBAZONES OF THE HETEROCYCLIC SERIES. LI. RECYCLIZATION OF ISATIN α-THIOACYLHYDRAZONES

Tomchin, A. B.

, p. 779 - 789 (2007/10/02)

2-Thiosemicarbazones and other thioacylhydrazones of isatin undergo recyclization in an acidic medium (and also in the absence of the acid in the case of thiobenzylhydrazones).The five-membered ring is first cleaved with the addition of water and the form

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