4672-49-5Relevant academic research and scientific papers
Grafting of polymeric platforms on gold by combining the diazonium salt chemistry and the photoiniferter method
Ahmad, Randa,Mocaer, Adrien,Gam-Derouich, Sarra,Lamouri, Aazdine,Lecoq, Hélène,Decorse, Philippe,Brunet, Philippe,Mangeney, Claire
, p. 12 - 20 (2015)
The grafting of stable and strongly attached polymeric platforms on gold is a key factor for successful applications in biology, catalysis and sensing. Here, we report on the use of a combination of the iniferter method and the diazonium salt chemistry for preparing smart polymeric platforms attached through covalent bonds on gold. For this, bifunctional molecules bearing aryl diazonium coupling agents for anchoring on gold and N,N-diethyldithiocarbamate groups for initiating the growth of polymer chains were used. These two moieties were separated by oligo(ethylene oxide) spacers of various lengths allowing a fine tuning of the hydrophilic properties of the grafted photoinitiator layers. Cross-linked copolymers of methacrylic acid (MAA) and N,N′-methylenebisacrylamide (MBAm) were then grown from the gold surfaces under UV light. The polymer films were characterized in terms of chemical composition and wettability by X-ray photoelectron spectroscopy and contact angle measurements, respectively. The grafting procedure was simple, rapid and effective in producing polymer-grafted Au surfaces at room temperature. The diethyldithiocarbamil groups remaining at the end of the growing tethered chains could then be easily exchanged by a UV-light induced radical-exchange experiment in order to obtain terminal amino moieties able to immobilize citrate-capped gold nanoparticles, through electrostatic interactions. The results obtained in the present work highlight the efficiency of the diazonium salt chemistry coupled to the photo-iniferter based surface grafting approach to spontaneously functionalize gold surfaces through covalent bonds. This strategy open new opportunities for the preparation of "smart" hybrid platforms made of pH-responsive polymers and nanoparticle assemblies.
Greener synthesis of dimethyl carbonate from carbon dioxide and methanol using a tunable ionic liquid catalyst
Pawar, Atul A.,Chaugule, Avinash A.,Kim, Hern
, p. 1252 - 1265 (2020/02/06)
Several types of ionic liquids (ILs) performance towards dimethyl carbonate (DMC) synthesis using cheap reactant (methanol) and waste CO2 which is abundantly available in the environment are discussed. We synthesized ILs with cheap raw materials such as ethylene glycol. The main aim of this study is to synthesize efficient catalysts for the production of profitable fuel additives. ILs show high thermal stability, less viscosity, and low vapor pressure. In addition, some ILs have high CO2 absorption capacity due to moderate acid-base properties. These ILs reversibly capture more CO2 which is more efficient towards mass transport of methanol at optimum reaction conditions which enhance the DMC yield. This catalytic system is easily reusable for several reactions without decreased performance under the same reaction conditions. These reaction conditions had an effect on the synthesis of DMC. Temperature, pressure, IL loading, and IL/DMAP ratio were fine tuned. We propose a mechanism which the reaction may follow. The synthesized ILs required moderate reaction conditions and reduce waste gases (CO2) from the environments as they have high CO2 absorption capacity compared to the metal oxide catalyst. Therefore, this catalytic system helps and gives new direction to synthesize new catalyst for other application.
Phenyl pyrazoline compound with bioactivity and preparation method and application thereof
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Paragraph 0059; 0060; 0064, (2019/08/26)
The invention discloses a phenyl pyrazoline compound shown as a formula (I) and a preparation method and application thereof. R, R1, R2, R3 and R4 in the formula are defined in the specification. Thecompound shown as the formula (I) has herbicidal, insecticidal/acaricidal or bactericidal bioactivity and has high activity especially on weeds.
TRANSPARENT BODY PRODUCTION METHOD, TRANSPARENT BODY, AND AMORPHOUS BODY
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Paragraph 0109; 0110, (2017/10/10)
A transparent body production method that includes subjecting the compound represented by formula (1) to heating at a temperature equal to or greater than the melting point of said compound. In formula (1), each of W1 and W2 is the group represented by formula (2) in which the ring Z is an aromatic hydrocarbon ring, X is a single bond or —S—, R1 is a single bond or an alkylene group having 1-4 carbon atoms, R2 is a specific substituent, and m is an integer of 0 or higher, the group represented by formula (4) is —OH— or a (meth)acryloyloxy group, each of the rings Y1 and Y2 is an aromatic hydrocarbon ring, R is a single bond or a specific divalent group, each of R3a and R3b is —CN, a halogen group, or a monovalent hydrocarbon group, and each of n1 and n2 is an integer of 0-4.
PREPARATION OF AMMONIUM OR PHOSPHONIUM BORATE SALTS
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Page/Page column 19; 20, (2017/12/27)
A process for preparing an ammonium or phosphonium borate salt KA containing a cation K and an anion A comprising the steps (a) providing a melt of a borate salt K1A, (b) adding a solution of an ammonium or phosphonium salt KA1 in a solvent or solvent mixture wherein K is an organic ammonium or phosphonium cation; A is a borate anion of formula (la) or (lb)
CT gastrointestinal tract contrast agent and application thereof
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Paragraph 0048, (2017/08/30)
The invention relates to the field of nonionic X-ray contrast agents, in particular to a nonionic polymer iodine contrast agent and a contrast agent composition containing the compound. The compound has more superior physical and chemical properties compared with a nonionic dimer contrast agent in the prior art, has osmotic pressure closer to human blood and low viscosity and is applicable to various occasions, especially in CT gastrointestinal tract contrast.
COMPOSITION CONTAINING VINYL-GROUP-CONTAINING COMPOUND
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Paragraph 0401; 0402, (2016/04/20)
A composition containing a novel vinyl-group-containing compound. This composition contains a vinyl-group-containing compound represented by general formula (1). In the formula: W1 and W2 represent a group represented by general formula (2) (where a ring (Z) is an aromatic hydrocarbon ring, X is a single bond or —S—, R1 is a single bond or a C1-4 alkylene group, R2 is a specific substituent group such as a monovalent hydrocarbon, and m is an integer equal to 0 or higher), a group represented by general formula (4) (where the ring (Z), X, R1, R2, and m are as previously stated), a hydroxyl group, or a (meth)acryloyloxy group; rings (Y1, Y2) are aromatic hydrocarbon rings; R represents a single bond or a specific divalent group; R3a and R3b represent a cyano group, a halogen atom, or a monovalent hydrocarbon group; and n1 and n2 are integers of 0-4.
PRODUCTION METHOD OF VINYL GROUP-CONTAINING COMPOUND
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Paragraph 0128, (2017/04/03)
PROBLEM TO BE SOLVED: To provide a new production method of a vinyl group-containing compound having a fluorene skeleton (9,9-bisphenyl fluorene skeleton or the like) that is known for having excellent functions in optical characteristics such as a transmittance for light and a refractive index and in thermal characteristics such as heat resistance. SOLUTION: The production method of a vinyl group-containing compound includes: a decoloration step of removing a colored substance from a crude product containing a hydroxyl group-containing compound represented by 6,6-(9-fluorenylidene)-2,2-dinaphthol by use of alcohol to obtain a purified product containing the hydroxyl group-containing compound; and a reaction step of obtaining a vinyl group-containing compound represented by compound 1 or compound 4 below from the purified product. SELECTED DRAWING: None COPYRIGHT: (C)2016,JPOandINPIT
VINYL-GROUP-CONTAINING FLUORENE COMPOUND
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Paragraph 0134-0135, (2016/03/22)
A novel vinyl-group-containing fluorene compound and a method for producing the same, a polymerizable monomer and cross-linking agent including this compound, a leaving-group-containing fluorene compound, a monovinyl-group-containing fluorene compound, and methods for producing the same. This vinyl-group-containing fluorene compound is represented by formula (1). In the formula, W1 and W2 represent a group represented by formula (2), a group represented by formula (4), a hydroxyl group, or a (meth)acryloyloxy group, R3a and R3b represent a cyano group, a halogen atom, or a monovalent hydrocarbon, and n1 and n2 are integers of 0-4. In formulas (2) and (4), a ring (Z) is an aromatic hydrocarbon ring, X is a single bond or a group represented by —S—, R1 is a single bond or a C1-4 alkylene group, R2 is a specific substituent group such as a monovalent hydrocarbon, and m is an integer of 0 or greater.
In vitro antiplasmodial activity of triazole-linked chloroquinoline derivatives synthesized from 7-chloro-N-(prop-2-yn-1-yl)quinolin-4-amine
Taleli, Lebusetsa,De Kock, Carmen,Smith, Peter J.,Pelly, Stephen C.,Blackie, Margaret A.L.,Van Otterlo, Willem A.L.
, p. A4163 - A4171 (2015/08/03)
The synthesis and in vitro evaluation of novel triazole-linked chloroquinoline derivatives as potential antiplasmodial agents against Plasmodium falciparum is reported. The 15 synthesized target compounds were obtained by means of a copper(I)-mediated click reaction between a variety of 1,2- and 1,3-azidoamines and 7-chloro-N-(prop-2-yn-1-yl)quinolin-4-amine in moderate to good yields (53-85%). The compounds were screened for antiplasmodial activity against NF54 chloroquine-sensitive and Dd2 chloroquine-resistant strains, alongside chloroquine and artesunate as reference compounds. Six of the test compounds revealed a 3-5 fold increase in antiplasmodial activity against chloroquine-resistant strain Dd2 compared to chloroquine. Among the six compounds with good antiplasmodial activity, a reduced cross-resistance relative to artesunate (>3 fold in comparison to chloroquine) was observed, mainly in derivatives that incorporated chloroquine-resistance reversing pharmacophores. A general trend for reduced chloroquine cross-resistance was also detected among 12 out of the 15 compounds tested.
