51138-45-5

Basic information

• Product Name: Phenol, 2-(3-methyl-1-phenyl-1H-pyrazol-5-yl)-
• CAS NO: 51138-45-5
• Molecular Formula: C16H14N2O
• Molecular Weight: 250.3
• Mol File: 51138-45-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Phenol, 2-(3-methyl-1-phenyl-1H-pyrazol-5-yl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 2-(3-methyl-1-phenyl-1H-pyrazol-5-yl)-(51138-45-5)
• EPA Substance Registry System: Phenol, 2-(3-methyl-1-phenyl-1H-pyrazol-5-yl)-(51138-45-5)

Safety Data

• Hazardous Substances Data: 51138-45-5(Hazardous Substances Data)

Usage

General Description

Phenol, 2-(3-methyl-1-phenyl-1H-pyrazol-5-yl)-, also known as 5-Methyl-2-(3-methyl-1-phenyl-1H-pyrazol-5-yl)phenol, is a chemical compound with the molecular formula C16H14N2O. It is a derivative of phenol that contains a pyrazole ring and a methyl group. Phenol, 2-(3-methyl-1-phenyl-1H-pyrazol-5-yl)- has potential applications in the pharmaceutical and agrochemical industries, as it is a building block for the synthesis of various pharmaceutical drugs and agrochemicals. Its structure and properties make it useful for the development of new drugs with diverse biological activities. However, its potential toxicity and environmental impact should be carefully assessed before its widespread use.

Upstream product

• 5751-48-4 2-methylchromone 
• 100-63-0 phenylhydrazine 
• 51138-52-4 2-methylbenzopyran-4-thione 
• 16636-62-7 1-(2'-hydroxyphenyl)butane-1,3-dione 
• 931-55-5 phenyl-diazene 
• 64-17-5 ethanol 
• 10037-20-4 3-acetyl-2-methyl-4-oxo-4H-<1>benzopyran 
• 67140-88-9 2-Methyl-4-oxo-4H-<1>benzopyran-3-carbonitrile 
• 51751-37-2 2-Methyl-4-oxo-4H-<1>benzopyran-3-carboxylic acid 
• 59-88-1 phenylhydrazine hydrochloride 

Relevant articles and documents

Reaction of aryl and heterocyclyhydrazines with 2-methylchromone: Structural investigation of the products

Reaction of 2-methylchromone (2) with phenylhydrazine provides 3-methyl-5-(o-hydroxyphenyl)-1-phenylpyrazole (6) as a major product. In contrast under similar conditions, heterocyclyhydrazines (8a-c) yield exclusively 5-ethyl-3-(o-hydroxyphenyl)-1-heterocyclylpyrazoles (9a-c). The structural assignments are based on an unambiguous synthesis and an analysis of NMR (1H and 13C) spectral data.

INVESTIGATIONS IN THE CHROMONE SERIES. PART XI. REACTIONS OF METHYLCHROMONES AND METHYL-4-THIOCHROMONES WITH PHENYLHYDRAZINE

Reactions of 6-methyl-, 2-methyl- and 2,8-dimethylchromones, as well as of 6-methyl-, 8-methyl- and 2,8-dimethyl-4-thiochromones with phenylhydrazine have been investigated.A lack of reactivity in thiocarbonyl group in 4-thiochromone system has been established.Intermediate products of reactions have been separated, their structure established and the reaction course described.