51490-06-3

Basic information

• Product Name: Ethanone, 1,2-bis(4-methylphenyl)-
• CAS NO: 51490-06-3
• Molecular Formula: C16H16O
• Molecular Weight: 224.302
• Mol File: 51490-06-3.mol
• Article Data: 35

Chemical Properties

• CAS DataBase Reference: Ethanone, 1,2-bis(4-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1,2-bis(4-methylphenyl)-(51490-06-3)
• EPA Substance Registry System: Ethanone, 1,2-bis(4-methylphenyl)-(51490-06-3)

Safety Data

• Hazardous Substances Data: 51490-06-3(Hazardous Substances Data)

Upstream product

• 2789-88-0 1,2-bis(4-methylphenyl)acetylene 
• 105-39-5 chloroacetic acid ethyl ester 
• 4294-57-9 para-methylphenylmagnesium bromide 
• 29875-07-8 (4-methylbenzyl)magnesium chloride 
• 104-85-8 para-methylbenzonitrile 
• 1218-89-9 4,4'-dimethylbenzoin 
• 766-97-2 4-n-methylphenylacetylene 
• 624-31-7 4-tolyl iodide 
• 40030-78-2 4,4'-dimethylbenzil monohydrazone 
• 122-00-9 para-methylacetophenone 
• 108-88-3 toluene 
• 5173-28-4 1,2-di-p-tolylethane-1,2-diol 
• 589-18-4 4-Methylbenzyl alcohol 
• 2947-61-7 (4-methylphenyl)acetonitrile 

Downstream Products

• 6629-83-0 4,4',4-(ethene-1,1,2-triyl)tris(methylbenzene) 
• 112323-95-2 1,1,2-tri-p-tolyl-ethanol 
• 112379-71-2 1-anisyl-1,2-ditolyl-ethanol 
• 3457-48-5 1,2-di(4-methylphenyl)-1,2-ethanedione 
• 104-87-0 4-methyl-benzaldehyde 
• 99-94-5 p-Toluic acid 
• 65-85-0 benzoic acid 
• 622-47-9 4-tolylacetic acid 
• 108-88-3 toluene 
• 54881-85-5 1,2-di-4-methylphenylethanol 
• 56186-30-2 Acetic acid 1-(4-methyl-benzoyl)-2-oxo-1,2-di-p-tolyl-ethyl ester 
• 73896-21-6 C₁₆H₁₇NO 

Relevant articles and documents

Electrochemical oxidation-induced benzyl C–H carbonylation for the synthesis of aromatic α-diketones

Electrochemical oxidation-induced direct carbonylation of benzyl C–H bond for the synthesis of aromatic α-diketones is described. In this process, tetrabutylammonium iodide (nBu4NI) not only acts as an electrolyte, but its iodine anion is oxidized to an iodine radical at the anode, acting as a hydrogen atom transfer agent. The iodine radical extracts the benzyl hydrogen atom and causes the carbonylation of the benzyl position, where O2 in the air is used as an oxygen source.

Cobalt(II)-Catalyzed Stereoselective Olefin Isomerization: Facile Access to Acyclic Trisubstituted Alkenes

Stereoselective synthesis of trisubstituted alkenes is a long-standing challenge in organic chemistry, due to the small energy differences between E and Z isomers of trisubstituted alkenes (compared with 1,2-disubstituted alkenes). Transition metal-catalyzed isomerization of 1,1-disubstituted alkenes can serve as an alternative approach to trisubstituted alkenes, but it remains underdeveloped owing to issues relating to reaction efficiency and stereoselectivity. Here we show that a novel cobalt catalyst can overcome these challenges to provide an efficient and stereoselective access to a broad range of trisubstituted alkenes. This protocol is compatible with both mono- and dienes and exhibits a good functional group tolerance and scalability. Moreover, it has proven to be a useful tool to construct organic luminophores and a deuterated trisubstituted alkene. A preliminary study of the mechanism suggests that a cobalt-hydride pathway is involved in the reaction. The high stereoselectivity of the reaction is attributed to both a π-πstacking effect and the steric hindrance between substrate and catalyst.

Diazaphosphinyl radical-catalyzed deoxygenation of α-carboxy ketones: A new protocol for chemo-selective C-O bond scission: Via mechanism regulation

C-O bond cleavage is often a key process in defunctionalization of organic compounds as well as in degradation of natural polymers. However, it seldom occurs regioselectively for different types of C-O bonds under metal-free mild conditions. Here we report a facile chemo-selective cleavage of the α-C-O bonds in α-carboxy ketones by commercially available pinacolborane under the catalysis of diazaphosphinane based on a mechanism switch strategy. This new reaction features high efficiency, low cost and good group-tolerance, and is also amenable to catalytic deprotection of desyl-protected carboxylic acids and amino acids. Mechanistic studies indicated an electron-transfer-initiated radical process, underlining two crucial steps: (1) the initiator azodiisobutyronitrile switches originally hydridic reduction to kinetically more accessible electron reduction; and (2) the catalytic phosphorus species upconverts weakly reducing pinacolborane into strongly reducing diazaphosphinane. This journal is