52007-97-3

Basic information

• Product Name: N-(2-phenylethyl)propan-2-amine
• Synonyms: (2-phenylethyl)(propan-2-yl)amine
• CAS NO: 52007-97-3
• Molecular Formula: C₁₁H₁₇N
• Molecular Weight: 163.2594
• Mol File: 52007-97-3.mol
• Article Data: 20

Chemical Properties

• Boiling Point: 235.337°C at 760 mmHg
• Flash Point: 95.502°C
• Density: 0.902g/cm³
• Vapor Pressure: 0.05mmHg at 25°C
• Refractive Index: 1.5
• CAS DataBase Reference: N-(2-phenylethyl)propan-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-phenylethyl)propan-2-amine(52007-97-3)
• EPA Substance Registry System: N-(2-phenylethyl)propan-2-amine(52007-97-3)

Safety Data

• Hazardous Substances Data: 52007-97-3(Hazardous Substances Data)

Usage

General Description

N-(2-phenylethyl)propan-2-amine, also known as N,alpha-Diethylphenylethylamine or N-isopropylbenzaldehyde, is a synthetic chemical compound with a molecular formula C11H17N. It is classified as an amphetamine derivative and operates as a central nervous system (CNS) stimulant. The chemical structure of N-(2-phenylethyl)propan-2-amine is similar to other amphetamine compounds, and it has been used recreationally for its stimulating effects on the brain and body. However, its use is illegal in many countries and is considered a controlled substance due to its potential for misuse, addiction, and harmful side effects such as increased heart rate, blood pressure, and risk of stroke or heart attack. Additionally, the long-term effects and safety of N-(2-phenylethyl)propan-2-amine are not well understood, and its use is not recommended for any medical or therapeutic purposes.

Upstream product

• 64-04-0 phenethylamine 
• 108-18-9 diisopropylamine 
• 30533-08-5 N-methyl-N-nitroso-2-propanamine 
• 100-39-0 benzyl bromide 
• 75-31-0 isopropylamine 
• 536-74-3 phenylacetylene 
• 31349-66-3 methyl 2-((phenethylcarbamoyl)oxy)benzoate 
• 1943-82-4 phenethyl isocyanate 
• 123-42-2 4-Hydroxy-4-methyl-2-pentanone 
• 67-63-0 isopropyl alcohol 
• 103-82-2 phenylacetic acid 
• 122-78-1 phenylacetaldehyde 
• 75-26-3 isopropyl bromide 
• 5215-54-3 N-isopropyl-2-phenylacetamide 

Downstream Products

• 55246-61-2 isopropyl(phenethyl)carbamoyl chloride 
• 883973-32-8 (S)-2-(3-Isopropyl-3-phenethyl-ureido)-3-phenyl-propionic acid 
• 883973-43-1 2-(3-isopropyl-3-phenethyl-ureido)-N-methoxy-N-methyl-3-phenyl-propionamide 
• 3647-71-0 N-benzyl-2-phenylethylamine 
• 117106-15-7 4-methyl-1-phenethylazetidin-2-one 
• 883973-88-4 (S)-2-(3-Isopropyl-3-phenethyl-ureido)-3-phenyl-propionic acid methyl ester 

Relevant articles and documents

π ligands in alkaline earth complexes

π ligands such as olefins and alkynes bind intramolecularly to the metal atom in d0 complexes of the large alkaline earths (Ae) calcium and strontium supported by fluoroalkoxo ligands with dangling unsaturated C=C or C=C bonds, and having the amide N(SiMe

Catalyst-Free Reductive Coupling of Aromatic and Aliphatic Nitro Compounds with Organohalides

A rare reductive coupling of nitro compounds with organohalides has been realized. The reaction is initiated by a partial reduction of the nitro group to a nitrenoid intermediate. Therefore, not only aromatic but also aliphatic nitro compounds are efficiently transformed into monoalkylated amines, with organohalides as the alkylating agent. Given the innate reactivity of the nitrenoid, a catalyst is not required, resulting in a high tolerance for aryl halide substituents in both starting materials.

Synthesis of β-Lactams by Palladium(0)-Catalyzed C(sp3)?H Carbamoylation

A general and user-friendly synthesis of β-lactams is reported that makes use of Pd0-catalyzed carbamoylation of C(sp3)?H bonds, and operates under stoichiometric carbon monoxide in a two-chamber reactor. This reaction is compatible with a range of primary, secondary and activated tertiary C?H bonds, in contrast to previous methods based on C(sp3)?H activation. In addition, the feasibility of an enantioselective version using a chiral phosphonite ligand is demonstrated. Finally, this method can be employed to synthesize valuable enantiopure free β-lactams and β-amino acids.