52007-97-3Relevant articles and documents
π ligands in alkaline earth complexes
Ro?ca, Sorin-Claudiu,Caytan, Elsa,Dorcet, Vincent,Roisnel, Thierry,Carpentier, Jean-Fran?ois,Sarazin, Yann
, p. 1269 - 1277 (2017)
π ligands such as olefins and alkynes bind intramolecularly to the metal atom in d0 complexes of the large alkaline earths (Ae) calcium and strontium supported by fluoroalkoxo ligands with dangling unsaturated C=C or C=C bonds, and having the amide N(SiMe
Catalyst-Free Reductive Coupling of Aromatic and Aliphatic Nitro Compounds with Organohalides
Rauser, Marian,Eckert, Raphael,Gerbershagen, Max,Niggemann, Meike
supporting information, p. 6713 - 6717 (2019/04/14)
A rare reductive coupling of nitro compounds with organohalides has been realized. The reaction is initiated by a partial reduction of the nitro group to a nitrenoid intermediate. Therefore, not only aromatic but also aliphatic nitro compounds are efficiently transformed into monoalkylated amines, with organohalides as the alkylating agent. Given the innate reactivity of the nitrenoid, a catalyst is not required, resulting in a high tolerance for aryl halide substituents in both starting materials.
Synthesis of β-Lactams by Palladium(0)-Catalyzed C(sp3)?H Carbamoylation
Dailler, David,Rocaboy, Ronan,Baudoin, Olivier
supporting information, p. 7218 - 7222 (2017/06/13)
A general and user-friendly synthesis of β-lactams is reported that makes use of Pd0-catalyzed carbamoylation of C(sp3)?H bonds, and operates under stoichiometric carbon monoxide in a two-chamber reactor. This reaction is compatible with a range of primary, secondary and activated tertiary C?H bonds, in contrast to previous methods based on C(sp3)?H activation. In addition, the feasibility of an enantioselective version using a chiral phosphonite ligand is demonstrated. Finally, this method can be employed to synthesize valuable enantiopure free β-lactams and β-amino acids.