52686-70-1Relevant academic research and scientific papers
alpha-aryl or alkyl substituted borane adduct, preparation method and applications thereof
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Paragraph 0305-0308; 0310-0312; 0314-0315, (2020/01/25)
The invention relates to an alpha-aryl or alkyl substituted borane adduct, a preparation method and applications thereof, specifically to preparation of an alpha-aryl or alkyl substituted borane adduct by carrying out a reaction on hydrazone as an unstabl
Catalytic Asymmetric Formal Insertion of Aryldiazoalkanes into the C-H Bond of Aldehydes: Synthesis of Enantioenriched Acyclic α-Tertiary Aryl Ketones
Kang, Byung Chul,Nam, Dong Guk,Hwang, Geum-Sook,Ryu, Do Hyun
supporting information, p. 4810 - 4813 (2015/10/12)
A novel, catalytic enantioselective route to synthesize a variety of α-tertiary aryl ketones via a boron Lewis acid promoted formal insertion of aryldiazoalkane into the C-H bond of both aromatic and aliphatic aldehydes is described. In the presence of ch
A Novel Synthesis of Arylsulfonyl Hydrazine Derivatives Via the Reaction of Arylsulfonyl Hydrazone Salts and Hydrazonoyl Chlorides
Khalili, Gholamhossein
, p. 1882 - 1886 (2015/10/29)
An efficient method for the synthesis of arylsulfonyl hydrazines and diazo compounds via arylsulfonyl hydrazone salts is described. The reaction was performed in DMF using hydrazonoyl chlorides and sodium arylsulfonyl hydrazones, which were easily prepare
Diverse alkanones by catalytic carbon insertion into the formyl C-H bond. Concise access to the natural precursor of achyrofuran
Wommack, Andrew J.,Moebius, David C.,Travis, Austin L.,Kingsbury, Jason S.
supporting information; experimental part, p. 3202 - 3205 (2009/11/30)
Over a century ago, the first reactions of diazomethane with aldehydes delivered methyl ketones. In the interim, aldehydes have been homologated with trimethylsilyldiazomethane, diazoacetates, and aryldiazomethanes, on rare occasion with catalysis. This work describes a mild procedure for convergent ketone assembly from nonstabilized diazoalkanes, including examples of chiral ketone synthesis with disubstituted (internal) nucleophiles. The method's remarkable tolerance to steric crowding is showcased in a simple approach to achyrofuran, a complex dibenzofuran.
The β-heteroatom effect on carbenes
Lambert, Joseph B.,Liu, Xiaoyang
, p. 9989 - 9996 (2007/10/03)
The β-thiophosphinoyl carbene PhCCH2P(S)Ph2 (5) has been prepared by irradiation of the corresponding diazo compound. The relative rates for insertion into the OH bond of methanol and for addition to the double bond of 2-methyl-2-but
1,2-Hydrogen migration and alkene formation in the photoexcited states of alkylphenyldiazomethanes
?elebi, Sol,Leyva, Soccoro,Modarelli, David A.,Platz, Matthew S.
, p. 8613 - 8620 (2007/10/02)
Laser flash photolysis of alkylphenyldiazomethanes in the presence of pyridine produces easily detected ylides. The data indicate that photolysis of alkylphenyldiazomethanes leads to both carbene formation and direct formation of rearrangement products which do not derive from relaxed carbene intermediates.
A significant barrier to 1,2 hydrogen migration in singlet 1-phenylethylidene. A laser flash photolysis study
Sugiyama, Michelle H.,Celebi, Sol,Platz, Matthew S.
, p. 966 - 973 (2007/10/02)
Laser flash photolysis of 1-phenyldiazoethane in heptane releases 1-phenylethylidene which can be intercepted with pyridine to form an ylide (λmax> = 475 nm). Oxygen trapping experiments indicate that relaxation of singlet 1-phenylethylidene to
CYCLOADDITIONS OF DISUBSTITUTED DIAZO COMPOUNDS TO P-CHLORO(BISTRIMETHYLSILYL) METHYLENE PHOSPHINE.
Thoraval, J. Y.,Nagai, W.,Yeung Lam Ko, Y. Y. C.,Carrie, R.
, p. 3859 - 3868 (2007/10/02)
Disubstituted diazo compounds rapidly add to P-chloro (bistrimethylsilyl) methylene phosphine at low temperature. 1H, 31P and 13C NMR allow the characterization of the resulting cycloadducts and the establisment of the stereochemistry of the resulting cycloadducts which are potential precursors of ?3λ5 bis methylene phosphorane by nitrogen extrusion.
