527-52-6Relevant articles and documents
Two new steroidal glycosides from Cynanchum otophyllum Schneid
Yang, Xin-Xin,Bao, Yong-Rui,Wang, Li-Fen,Wang, Shuai,Bao, Li-Na,Guan, Yu-Peng,Meng, Xian-Sheng
, p. 285 - 288 (2015)
Two new C21 steroidal glycosides were isolated from Cynanchum otophyllum Schneid. Their structures were elucidated as qinyangshengenin-3-O-β-d-digitoxopyranoside (1) and rostratamine-3-O-β-d-cymaropyranosyl-(1 → 4)-β-d-digitoxopyranoside (2) on the basis of chemical and spectroscopic methods, including 1D and 2D NMR experiments.
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Smith
, p. 23,25 (1931)
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Triterpene glycosides and phenylpropane derivatives from Staurogyne concinnula possessing anti-angiogenic activity
Vo, Thanh-Hoa,Lin, Yu-Chi,Liaw, Chia-Ching,Pan, Wen-Pin,Cheng, Jing-Jy,Lee, Ching-Kuo,Kuo, Yao-Haur
, (2021/02/03)
After anti-angiogenic activity screening, the potential n-butanol layer partitioned from the ethanol extract of Staurogyne concinnula was conducted. Further purification by Diaion HP20 column and preparative HPLC chromatography, four undescribed triterpen
New Immunomodulating Polyhydroxypregnane Glycosides from the Roots of Cynanchum otophyllum C.K.Schneid.
Zhan, Zha-Jun,Bao, Shu-Min,Zhang, Yue,Qiu, Fei-Jun,Shan, Wei-Guang,Ma, Lie-Feng
, (2019/06/13)
Seven new polyhydroxypregnane glycosides, named cynotophyllosides P–V, together with three known analogs were isolated from the roots of Cynanchum otophyllum C.K.Schneid. Their structures were elucidated by a variety of spectroscopic techniques, as well as acid-catalyzed hydrolysis. All isolates were tested for their immunological activities in vitro against Con A- and LPS-induced proliferation of mice splenocytes. Immunoenhancing (for 1, 9) and immunosuppressive (for 2) activities were observed. Furthermore, cynotophylloside R (3) showed immunomodulatory as it enhanced the proliferation of splenocytes in low concentration and suppressed immune cells in concentration more than 1.0 μg/ml.
Two new steroidal saponins from the roots of Cynanchum limprichtii
Liu, Jia-Chuan,Yu, Li-Li,Tang, Ming-Xu,Lu, Xiao-Jie,Zhao, Dan,Wang, Hai-Feng,Chen, Gang,Su, Guang-Yue,Pei, Yue-Hu
, p. 875 - 882 (2017/11/29)
As a part of our continuing research for bioactive constituents from Cynanchum limprichtii Schltr., two new C21 steroidal glycosides limproside A (1) and limproside B (2) were isolated from the roots of Cynanchum limprichtii. Their structures were elucidated on the basis of 1D- and 2D-NMR spectroscopic data as well as HR-ESI-MS analysis. The cytotoxicity of two compounds against two selected human cancer cell lines was assayed.