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Benzene, 1,2,5-trimethoxy-3-(2-propenyl)-, also known as safrole, is an organic compound with the chemical formula C10H12O3. It is a colorless to pale yellow oily liquid with a strong, sweet odor. Safrole is a naturally occurring substance found in the roots and rhizomes of several plants, such as Sassafras albidum and Ocotea quixos. It is an important intermediate in the synthesis of various chemicals, including the illicit drug MDMA (ecstasy). Due to its potential health risks and association with the production of controlled substances, the sale and use of safrole are restricted in many countries.

5273-91-6

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5273-91-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 5273-91-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,2,7 and 3 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 5273-91:
(6*5)+(5*2)+(4*7)+(3*3)+(2*9)+(1*1)=96
96 % 10 = 6
So 5273-91-6 is a valid CAS Registry Number.

5273-91-6Relevant academic research and scientific papers

Towards an asymmetric synthesis of the bacterial peptide deformylase (PDF) inhibitor fumimycin

Hartmann, Caroline E.,Gross, Patrick J.,Nieger, Martin,Braese, Stefan

supporting information; experimental part, p. 5059 - 5062 (2010/04/04)

Studies towards the synthesis of the bacterial peptide deformylase (PDF) inhibitor fumimycin are reported. The synthetic approach features an organocatalytic access to the α,α-disubstituted amino acid unit and results in the synthesis of an advanced inter

Synthesis and hypolipidemic and antiplatelet activities of α-asarone isomers in humans (in vitro), mice (in vivo), and rats (in vivo)

Poplawski,Lozowicka,Dubis,Lachowska,Witkowski,Siluk,Petrusewicz,Kaliszan,Cybulski,Strzalkowska,Chilmonczyk

, p. 3671 - 3676 (2007/10/03)

A series of α-asarone isomers was synthesized and investigated for their hypolipidemic and antiplatelet activity. Considering the hypolipidemic activity in rats at a dose of 80 mg/kg/day, some isomers were more potent than clofibrate at 150 mg/kg. Compoun

Feeding-deterrent activity of α-asarone isomers against some stored Coleoptera

Poplewski, Janusz,Lozowicka, Bozena,Dubis, Alina T.,Lachowska, Barbara,Winiecki, Zbigiew,Nawrot, Jan

, p. 560 - 564 (2007/10/03)

All isomers of α-asarone [(E)-4-prop-1-enyl-1,2,5-trimethoxybenzene] were tested for their feeding deterrent activity against adults of Sitophilus granarius and Tribolium confusum and larvae of Trogoderma granarium and Tribolium confusum. (E)-2-prop-1-eny

Crystal structures of 1,2,5-trimethoxy-3-(1-propenyl)benzene and 1,3,5-trimethoxy-2-(1-propenyl)benzene

Wolska,Poplawski,Lozowicka

, p. 2331 - 2341 (2007/10/03)

The crystal structures of 1,2,5-trimethoxy-3-(1-propenyl)benzene (D) and 1,3,5-trimethoxy-2-(1-propenyl)benzene (F) have been determined by X-ray diffraction methods. The compounds crystallize in the monoclinic system, space group P21/c for (D)

STRUCTURE-ACTIVITY RELATIONSHIPS OF PHENYLPROPANOIDS AS GROWTH INHIBITORS OF THE GREEN ALGA SELENASTRUM CAPRICORNUTUM

Greca, Marina Della,Monaco, Pietro,Pollio, Antonino,Previtera, Lucio

, p. 4119 - 4124 (2007/10/02)

Twenty-seven commercial or synthetic phenylpropanoids have been tested in broth against the unicellular alga Selenastrum capricornutum.The antialgal activity seems to be linked to the number as well as to the position of the methoxyl group in the molecule.A slight effect of the side chain substitution was also observed. Key Word Index - Selenastrum capricornutum; allelochemicals; phenylpropanoids.

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