5355-17-9

Basic information

• Product Name: alpha-methoxy-p-cresol
• Synonyms: alpha-methoxy-p-cresol;4-(2-METHOXYETHYL)PHENOLMETHOTREATE;(4-Hydroxybenzyl)methyl ether;4-(Methoxymethyl)phenol;p-(MethoxyMethyl)phenol;alpha-Methoxy-p-cresol Phenol
• CAS NO: 5355-17-9
• Molecular Formula: C₈H₁₀O₂
• Molecular Weight: 138.1638
• EINECS: 226-334-9
• Mol File: 5355-17-9.mol
• Article Data: 23

Chemical Properties

• Melting Point: 82.5-83.5 °C
• Boiling Point: 222.8 °C at 760 mmHg
• Flash Point: 92.5 °C
• Appearance: /
• Density: 1.087 g/cm³
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 9.84±0.26(Predicted)
• CAS DataBase Reference: alpha-methoxy-p-cresol(CAS DataBase Reference)
• NIST Chemistry Reference: alpha-methoxy-p-cresol(5355-17-9)
• EPA Substance Registry System: alpha-methoxy-p-cresol(5355-17-9)

Safety Data

• Hazardous Substances Data: 5355-17-9(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Tetrahedron Letters, 30, p. 1939, 1989 DOI: 10.1016/S0040-4039(00)99619-9

Upstream product

• 67-56-1 methanol 
• 623-05-2 (4-hydroxyphenyl)methanol 
• 39720-27-9 4-acetoxybenzyl chloride 
• 80767-12-0 4-hydroxybenzyl acetate 
• 61661-14-1 -chlorid 
• 106-44-5 p-cresol 
• 123-08-0 4-hydroxy-benzaldehyde 
• 937-62-2 p-tolyl chloroformate 
• 15451-04-4 p-chloromethyl-phenyl chloroformate 
• 2937-64-6 4-(acetyloxy)benzyl acetate 
• 78507-15-0 Dimethano-1,4: 5,8 methylene-10 octahydro-1,4,4a,5,8,8a,9a,10a 9H, 10H-anthracenone-9 
• 124-41-4 sodium methylate 
• 61334-39-2 8-Ethoxycarbonyloxy-3-(4-ethoxycarbonyloxy-benzyl)-3,6,11-trimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocinium; iodide 

Downstream Products

• 1026335-66-9 4-(4-methoxymethyl-phenoxy)-thieno[2,3-c]pyridine-2-carboxylic acid methyl ester 
• 1026148-21-9 4-(4-methoxymethyl-phenoxy)-thieno[2,3-c]pyridine-2-carboxylic acid 
• 180521-90-8 4-(Methoxy-trimethylsilanyl-methyl)-phenol 
• 180521-89-5 1-(Methoxy-trimethylsilanyl-methyl)-4-trimethylsilanyloxy-benzene 
• 675855-60-4 4-undecylphenyl trifluoromethanesulfonate 
• 675855-56-8 1-ethoxymethoxy-4-undecylbenzene 
• 675855-57-9 1-ethoxymethoxy-4-isobutyl-benzene 
• 35117-05-6 1-ethoxymethoxy-4-methylbenzene 
• 123-08-0 4-hydroxy-benzaldehyde 
• 675855-49-9 1-ethoxymethoxy-4-methoxymethylbenzene 
• 180521-88-4 (4-Methoxymethyl-phenoxy)-trimethyl-silane 

Relevant articles and documents

A method of manufacturing a lignocellulose compd. (by machine translation)

PROBLEM TO BE SOLVED: To provide a production method capable of obtaining a high-purity benzyl ether compound at excellent yield by a simple method. SOLUTION: This invention relates to a method for producing a benzyl ether compound represented by general formula (In the formula, R1-R3each represents a hydrogen atom, a 1-3C alkyl group, or a 1-3C alkoxy group, and R4represents a 1-3C alkyl group) which is obtained by reacting a benzyl alcohol compound having a phenol group with an aliphatic alcohol compound in the presence of an inorganic acid and a nitro compound. COPYRIGHT: (C)2013,JPO&INPIT

Selective synthesis of p-hydroxybenzaldehyde by liquid-phase catalytic oxidation of p-cresol

Liquid-phase oxidation of p-cresol over insoluble cobalt oxide (Co 3O4) catalyst under elevated pressure of air gave 95% selectivity to p-hydroxybenzaldehyde, an important flavoring intermediate. The selectivity to p-hydroxybenzaldehyde could be enhanced by manipulating the concentrations of p-cresol, sodium hydroxide, and catalyst and the partial pressure of oxygen in such a way that the byproducts normally encountered in this oxidation process were eliminated or minimized significantly.