5418-20-2

Basic information

• Product Name: ({[(benzylsulfanyl)(phenyl)methyl]sulfanyl}methyl)benzene
• Synonyms: (Bis(benzylthio)methyl)benzene
• CAS NO: 5418-20-2
• Molecular Formula: C₂₁H₂₀S₂
• Molecular Weight: 336.5135
• Mol File: 5418-20-2.mol
• Article Data: 16

Chemical Properties

• Boiling Point: 463.6°C at 760 mmHg
• Flash Point: 232.5°C
• Density: 1.165g/cm³
• Vapor Pressure: 2.48E-08mmHg at 25°C
• Refractive Index: 1.65
• CAS DataBase Reference: ({[(benzylsulfanyl)(phenyl)methyl]sulfanyl}methyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: ({[(benzylsulfanyl)(phenyl)methyl]sulfanyl}methyl)benzene(5418-20-2)
• EPA Substance Registry System: ({[(benzylsulfanyl)(phenyl)methyl]sulfanyl}methyl)benzene(5418-20-2)

Safety Data

• Hazardous Substances Data: 5418-20-2(Hazardous Substances Data)

Usage

General Description

The chemical compound "({[(benzylsulfanyl)(phenyl)methyl]sulfanyl}methyl)benzene" is a complex molecule that contains multiple benzene rings and sulfur groups. Its structure consists of a central benzene ring with two benzylsulfanyl groups attached to it, each of which is further connected to a phenylmethylsulfanyl group. This arrangement results in a highly branched and intricate molecule with multiple sulfur and aromatic carbon groups. The compound's structure suggests that it may have potential uses in organic synthesis and the development of new materials.

Upstream product

• 621-08-9 Dibenzyl sulfoxide 
• 100-52-7 benzaldehyde 
• 100-53-8 phenylmethanethiol 
• 150-60-7 dibenzyl disulphide 
• 100-44-7 benzyl chloride 
• 16601-40-4 S-benzyl phenyl-methanethiosulfonate 
• 141-52-6 sodium ethanolate 
• 7695-69-4 bis(phenylthio)methylbenzene 
• 7334-52-3 benzaldehyde diethyldithioacetal 
• 856297-64-8 α-benzylsulfanyl-benzyl alcohol 
• 71-43-2 benzene 
• 538-74-9 dibenzyl sulfide 
• 74-88-4 methyl iodide 
• 7647-01-0 hydrogenchloride 

Downstream Products

• 103-30-0 (E)-1,2-diphenyl-ethene 
• 103-29-7 1,1'-(1,2-ethanediyl)bisbenzene 
• 100-52-7 benzaldehyde 
• 150-60-7 dibenzyl disulphide 
• 538-74-9 dibenzyl sulfide 
• 62970-87-0 phenyl[bis(benzylsulfonyl)]methane 
• 581-55-5 benzylidene 1,1-diacetate 

Relevant articles and documents

Direct Synthesis of Unsymmetrical Dithioacetals

Dithioacetals are a frequently used motif in synthetic organic chemistry and have recently seen increasing attention as structural motif in promising antiviral agents against plant pathogens. Most existing reports, however, only discuss symmetrical dithioacetals. Examples of mixed dithioacetals are scarce and no general method for the selective synthesis of these compounds exists. Herein, a synthetically simple general one-step protocol was developed for the synthesis of a broad range of unsymmetrical dithioacetals consisting of one aromatic and one aliphatic thiol moiety from the corresponding aldehyde/thiol mixture. The mixed S,S-acetals were obtained in high yields, and a great variety of functional groups was tolerated. Kinetic control enabled an excellent selectivity in regard to the unsymmetrical dithioacetal.

An expeditious and efficient bromomethylation of thiols: Enabling bromomethyl sulfides as useful building blocks

A facile and highly efficient method for the bromomethylation of thiols, using paraformaldehyde and HBr/AcOH, has been developed, which advantageously minimizes the generation of highly toxic byproducts. The preparation of 22 structurally diverse α-bromomethyl sulfides illustrates the chemo-tolerant applicability while bromo-lithium exchange and functionalization sequences, free radical reductions, and additions of the title compounds demonstrate their synthetic utility.

Chemoselective and odorless transthioacetalization of acetals using α-oxo-ketene dithioacetals as thiol equivalents

Using α-oxo-ketene dithioacetals 1a as odorless thiol equivlents, an efficient and odorless transthioacetalization of acetals 2 has been developed. In the presence of MeCOCl in MeOH, the cleavage of 1a commences to generate thiols at both room and reflux temperatures, and the generated thiols then react with acetals 2 to give correspecting thioacetals 3 in good yield. This transthioacetalization is characterized by mild reaction conditions, simple procedure, good yields, and perfect chemoselectivity. It is noteworthy that only a very faint odor of thiols can be perceived during both the reaction and workup.