5432-07-5

Basic information

• Product Name: (2Z)-3-(4-methoxyphenyl)-2-phenylprop-2-enenitrile
• Synonyms: Benzene, 1-methoxy-4-(2-cyano-2-phenylethenyl); Benzene, 1-methoxy-4-(2-cyano-2-phenylethenyl)-; Benzeneacetonitrile, .alpha.-[(4-methoxyphenyl)methylene]-
• CAS NO: 5432-07-5
• Molecular Formula: C₁₆H₁₃NO
• Molecular Weight: 235.2805
• Mol File: 5432-07-5.mol
• Article Data: 28

Chemical Properties

• Boiling Point: 384.6°C at 760 mmHg
• Flash Point: 161.9°C
• Density: 1.12g/cm³
• Vapor Pressure: 4.03E-06mmHg at 25°C
• Refractive Index: 1.617
• CAS DataBase Reference: (2Z)-3-(4-methoxyphenyl)-2-phenylprop-2-enenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: (2Z)-3-(4-methoxyphenyl)-2-phenylprop-2-enenitrile(5432-07-5)
• EPA Substance Registry System: (2Z)-3-(4-methoxyphenyl)-2-phenylprop-2-enenitrile(5432-07-5)

Safety Data

• Hazardous Substances Data: 5432-07-5(Hazardous Substances Data)

Usage

General Description

The chemical "(2Z)-3-(4-methoxyphenyl)-2-phenylprop-2-enenitrile" is a compound with the molecular formula C17H15NO. It is classified as a nitrile, containing a cyano group (C≡N) attached to a 2-phenylprop-2-ene moiety, with a 4-methoxyphenyl group attached to the carbon-carbon double bond. (2Z)-3-(4-methoxyphenyl)-2-phenylprop-2-enenitrile is commonly used in organic synthesis and pharmaceutical research due to its potential biological activity. Additionally, it can be used as a precursor in the synthesis of various complex organic molecules, making it a valuable intermediate in chemical manufacturing processes.

Upstream product

• 141-52-6 sodium ethanolate 
• 140-29-4 phenylacetonitrile 
• 123-11-5 4-methoxy-benzaldehyde 
• 105-13-5 4-Methoxybenzyl alcohol 

Downstream Products

• 32970-78-8 2-phenyl-3-(4-methoxyphenyl)-propylnitrile 
• 82234-90-0 3-cyano-4-(4-methoxyphenyl)-2,3,5-triphenylpyrrolidine 
• 82925-30-2 3,3-Bis-<4-methoxy-phenyl>-2-phenyl-propionitril 
• 140-29-4 phenylacetonitrile 
• 63785-34-2 (2Z)-2,3-bis(4-methoxyphenyl)prop-2-enenitrile 
• 10077-32-4 (E)-α-phenyl-β-(p-methoxyphenyl) acrylonitrile 
• 52565-72-7 (E)-2-(4-methoxyphenyl)-3-(4-methoxyphenyl)acrylonitrile 
• 1346463-49-7 5-(4-methoxyphenyl)-4-phenylpenta-(2E,4Z)-dienoyl azide 
• 1346463-36-2 5-(4-methoxyphenyl)-4-phenylpenta-(2E,4Z)-dienoic acid 
• 69031-99-8 α-Phenyl-α(p-methoxybenzoyl)acetamid 

Relevant articles and documents

Enantiomerically Pure 5,13-Dicyano-9-oxa[7]helicene: Synthesis and Study

Optically pure dicyano oxa[7]helicenes and helicene-like molecules have been prepared and investigated for their optical behavior. The isomers of the intermediate 4,4′-biphenanthrene-3,3′-diol were resolved by physically separating their 1-menthyl carbona

Pyrenedione-Catalyzed α-Olefination of Nitriles under Visible-Light Photoredox Conditions

Herein, we report a combination of pyrenedione (PD) and KOtBu to achieve facile alcohol dehydrogenation under visible-light excitation, where aerobic oxygen is utilized as the terminal oxidant. The resulting carbonyl compound can be easily converted to vinyl nitriles in a single-pot reaction, at 60 °C in 6-8 h. This environmentally benign, organocatalytic approach has distinct advantages over transition-metal-catalyzed α-olefination of nitriles, which often operate at a significantly higher temperature for an extended reaction time.

Manganese Catalyzed α-Alkylation of Nitriles with Primary Alcohols

The manganese(I) complex bearing a bidentate hydrazone ligand efficiently catalyzes the α-alkylations of nitrile using primary alcohols as alkylating agents. α-Functionalized nitriles were selectively obtained in good to excellent yields. The reaction is environmentally benign, producing water as the sole byproduct. Both benzylic and aliphatic alcohols could be used and functional groups were tolerated.