5449-49-0

Basic information

• Product Name: biphenyl-2-yl benzoate
• CAS NO: 5449-49-0
• Molecular Formula: C₁₉H₁₄O₂
• Molecular Weight: 274.3133
• Mol File: 5449-49-0.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 471.9°C at 760 mmHg
• Flash Point: 199.8°C
• Density: 1.151g/cm³
• Vapor Pressure: 4.48E-09mmHg at 25°C
• Refractive Index: 1.609
• CAS DataBase Reference: biphenyl-2-yl benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: biphenyl-2-yl benzoate(5449-49-0)
• EPA Substance Registry System: biphenyl-2-yl benzoate(5449-49-0)

Safety Data

• Hazardous Substances Data: 5449-49-0(Hazardous Substances Data)

Upstream product

• 90-43-7 2-Phenylphenol 
• 65-85-0 benzoic acid 
• 4688-76-0 2-Biphenylboronic acid 
• 74542-54-4 N,N-phenyl-p-toluenesulfonylbenzamide 
• 2113-51-1 2-iodobiphenyl 
• 58585-84-5 1,3-dioxoisoindolin-2-yl benzoate 
• 591-50-4 iodobenzene 
• 201230-82-2 carbon monoxide 
• 2446-51-7 N-methoxybenzamide 
• 50978-45-5 3-oxobenzo[d]isothiazole-2(3H)-carbaldehyde 1,1-dioxide 
• 98-88-4 benzoyl chloride 
• 108-90-7 chlorobenzene 
• 129103-70-4 2-iodophenyl benzoate 
• 71-43-2 benzene 

Relevant articles and documents

Visible light-mediated transition metal-free esterification of amides with boronic acids

A novel strategy for visible light-mediated esterification of amides with boronic acids in air has been described. This method is characterized by mild reaction conditions and low cost owing to no need of any catalyst, which implies high potential utility in late-stage functionalization of amide drugs and materials.

Method for preparing carboxylate aryl type compound

The invention belongs to the field of drug synthesis and in particular relates to a method for preparing a carboxylate aryltype compound. The preparation method provided by the invention comprises thefollowing steps: providing a compound A of a formula a shown in the description, a compound B of a formula b shown in the description, an organic palladium complex, and a silver salt, wherein the organic palladium complex is composed of a palladium compound and a nitrogen-containing ligand; the nitrogen-containing ligand comprises an o-phenoline compound and/or a bipyridine compound; and mixing the compound A, the compound B, the organic palladium complex and the silver salt in a reaction solvent, and performing a reaction in an inert gas atmosphere, so as to obtain the carboxylate aryl typecompound of a formula I shown in the description. As the organic palladium complex and the silver salt are simultaneously used, direct selectivity C-O coupling of carboxylic acid and halogenated aromatic hydrocarbon is realized, and the method is applicable to a variety of carboxylic acid substrates and halogenated aromatic substrates, and is wide in compatibility and high in yield.

Oxime palladacycle in PEG as a highly efficient and recyclable catalytic system for phenoxycarbonylation of aryl iodides with phenols

In this report, we have developed a sustainable protocol for the synthesis of aromatic esters by a carbonylative method using di-μ-chlorobis [5-hydroxy-2-[1-(hydroxyimino-?N) ethyl] phenyl-?C] palladium (II) dimer (1) catalyst in PEG-400 as a greener and recyclable solvent. The reaction is carried out at room temperature using CO in a balloon. Good to excellent yield of various esters can be synthesize using this protocol. Direct insertion of CO moiety leads to the high atom and step economy. Compared to previous protocol this phosphine free approach for the synthesis of aromatic esters provides high Turnover Number (TON) and Turnover Frequency (TOF). Developed approach has an alternative route for use of conventional palladium precursor with high conversion and selectivity. The catalyst system and product can easily be separated using diethyl ether as a solvent. The Pd/PEG-400 system could be reused up to a fifth consecutive cycle without any loss of its activity and selectivity.