5517-60-2

Basic information

• Product Name: methyl 3'-O-benzoyl-2,3-O-isopropylidene-β-D-apiofuranoside
• Synonyms: methyl 3'-O-benzoyl-2,3-O-isopropylidene-β-D-apiofuranoside
• CAS NO: 5517-60-2
• Molecular Weight: 308.331
• Mol File: 5517-60-2.mol

Chemical Properties

• CAS DataBase Reference: methyl 3'-O-benzoyl-2,3-O-isopropylidene-β-D-apiofuranoside(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3'-O-benzoyl-2,3-O-isopropylidene-β-D-apiofuranoside(5517-60-2)
• EPA Substance Registry System: methyl 3'-O-benzoyl-2,3-O-isopropylidene-β-D-apiofuranoside(5517-60-2)

Safety Data

• Hazardous Substances Data: 5517-60-2(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 50-69-1 D-ribose 
• 67-64-1 acetone 
• 118967-96-7 ((3aR,4R,6aR)-6-bromo-2,2-dimethyl-tetrahydrofuro[3,4-d]-[1,3]dioxol-4-yl)methyl benzoate 
• 4099-85-8 ((3aR,4R,6R,6aR)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methanol 
• 98-88-4 benzoyl chloride 
• 36468-53-8 β-D-ribofuranose 

Downstream Products

• 2346620-55-9 molnupiravir acetonide 
• 362-42-5 2',3'-O-isopropylidenecytidine 
• 65-46-3 CYTIDINE 
• 115269-11-9 1,2,3-tri-O-acetyl-5-O-benzoyl-β-D-ribofuranose 
• 118967-99-0 methyl 5-O-(5-O-benzoyl-2,3-O-isopropylidene-α-D-ribofuranosyl)-2,3-O-isopropylidene-β-D-ribofuranoside 
• 118967-98-9 methyl 5-O-(5-O-benzoyl-2,3-O-isopropylidene-β-D-ribofuranosyl)-2,3-O-isopropylidene-β-D-ribofuranoside 
• 118968-01-7 6-O-(5-O-benzoyl-2,3-O-isopropylidene-α-D-ribofuranosyl)-1,2-5,6-di-O-isopropylidene-α-D-glucofuranose 
• 118968-00-6 3-O-(5-O-benzoyl-2,3-O-isopropylidene-α-D-ribofuranosyl)-1,2-5,6-di-O-isopropylidene-α-D-glucofuranose 
• 39925-12-7 methyl 1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-1,2,4-triazole-3-carboxylate 
• 36791-04-5 ribavirin 
• 39925-13-8 methyl 1-(2',3',3''-tri-O-benzoyl-apio-β-D-furanosyl)triazole-5-carboxylate 
• 60084-09-5 ethyl 2-(2',3',3''-tri-O-benzoyl-β-D-apiofuranosyl)thiazole-4-carboxylate 
• 23316-67-8 2,3,5-tri-O-benzoyl-β-D-ribofuranosyl-1-carbonitrile 
• 52783-53-6 methyl 2,3,3'-tri-O-benzoyl-β-D-apiofuranoside 

Relevant articles and documents

Conversion of: N- acyl amidines to amidoximes: A convenient synthetic approach to molnupiravir (EIDD-2801) from ribose

An efficient method is described for the preparation of molnupiravir (EIDD-2801) an antiviral agent via regioselective conversion of an N-acyl-nucleoside intermediate, generated through stereo and regioselective glycosylation of protected ribose and N4-acetyl cytosine, to an amidoxime. This method avoids use of expensive starting materials, enzymes, complex reagents, and cumbersome purification procedures.

Synthesis and biological evaluation of novel apio nucleosides with thiazole-4-carboxamide and 1,2,4-triazole-3-carboxamide

In view of biological activities of azole nucleosides and apio-dideoxynucleoside, novel apio nucleoside analogues (1 and 2) with thiazole and triazole base moiety were synthesized using 2,3-O-isopropylidene-apio-β -D-furanose (3), which was prepared from D-mannose.

A Simple Synthesis of α-D-Ribofuranosides

The glycosylation of various aglycones with 5-O-benzoyl-2,3-O-isopropylidene-β-D-ribofuranosyl bromide (2) has been studied under different reaction conditions.It is possible to obtain high yields of α-linked ribofuranosides using methanol or methyl-2,3-O