55449-79-1

Upstream product

• 103-26-4 methyl cinnamate 
• 140-10-3 (E)-3-phenylacrylic acid 
• 19713-73-6 methyl (2Z)-3-phenylprop-2-enoate 
• 100-52-7 benzaldehyde 
• 108009-65-0 threo-2,3-Bis(trimethylsiloxy)-3-phenylpropansaeure-trimethylsilylester 
• 69-96-5 dl-threo-phenylserine 
• 103-26-4 Methyl cinnamate 
• 103-41-3 (E)-cinnamic acid benzyl ester 
• 139165-61-0 (2S,3R)-2,3-dihydroxy-3-phenylpropionic acid benzyl ester 
• 5695-95-4 (2RS,3SR)-2,3-dihydroxy-3-phenyl-propionic acid 

Downstream Products

• 124649-67-8 methyl (2S,3R)-3-phenyl-2,3-dihydroxypropanoate 
• 144-62-7 oxalic acid 
• 100-52-7 benzaldehyde 
• 65-85-0 benzoic acid 
• 64-18-6 formic acid 
• 108-88-3 toluene 
• 55449-78-0 (2S,3S)-2,3-dihydroxy-3-phenyl-propionic acid 
• 56816-81-0 (2R,3S)-2,3-dihydroxy-3-phenyl-propionic acid 
• 5801-58-1 α-acetoxy-cinnamic acid 
• 81691-59-0 (2RS,3RS)-2,3-dihydroxy-3-phenyl-propionic acid methyl ester 
• 133520-58-8 [1-((4S,5R)-2,2-Dimethyl-5-phenyl-[1,3]dioxolan-4-yl)-meth-(Z)-ylidene]-((R)-2-methoxymethyl-pyrrolidin-1-yl)-amine 
• 133421-03-1 [1-((4R,5R)-2,2-Dimethyl-5-phenyl-[1,3]dioxolan-4-yl)-meth-(Z)-ylidene]-((R)-2-methoxymethyl-pyrrolidin-1-yl)-amine 
• 133421-02-0 erythro-2,2-Dimethyl-5-phenyl-1,3-dioxolan-4-carbonsaeure-ethylester 
• 133521-66-1 (4S,5R)-Ethyl 2,2-dimethyl-5-phenyl-1,3-dioxolane-4-carboxylate 

Relevant academic research and scientific papers

Supported osmates, process for preparation thereof, and a process for the preparation of chiral vicinal diols using supported osmate catalyst

The present invention provides a supported osmate useful as a reusable catalyst in the preparation of vicinal diols. The present invention also relates to a process for the preparation of supported osmates of the formula (S—NR3)2OsO4.nH2O wherein S is a support, R is an alkyl group, n is the number of water molecules and use thereof in the preparation of vicinal diols by asymmetric dihydroxylation (AD) of olefins in presence of cinchona alkaloid compounds.

Supported osmates, process for preparation thereof, and a process for the preparation of chiral vicinal diols using supported osmate catalyst

The present invention provides a supported osmate useful as a reusable catalyst in the preparation of vicinal diols. The present invention also relates to a process for the preparation of supported osmates of the formula (S—NR3)2OsO4.nH2O wherein S is a support, R is an alkyl group, n is the number of water molecules and use thereof in the preparation of vicinal diols by asymmetric dihydroxylation (AD) of olefins in presence of cinchona alkaloid compounds.

Process for the preparation of supported osmates

The present invention discloses a process for the preparation of a novel heterogeneous osmate catalyst of the general formula (S—NR3)2OsO4.nH2O wherein S is a support, R is an alkyl group, n is the number of water molecules by reacting potassium osmate with supported quaternary ammonium species in an aqueous solvent.

Preparation of new layered double hydroxides exchanged with osmate for asymmetric dihydroxylation of olefins to vicinal diols

LDH-osmate of the formula [MII(1?x)MIIIx(OH)2][OsO42?]x/2.zH2O wherein MIIis a divalent cation selected from the group consisting of Mg2+, Mn2+, Fe2+, Co2+, Ni2+, Cu2+, Zn2+and Ca2+and MIIIis a trivalent ion selected from the group consisting of Al3+, Cr3+, Mn3+, Fe3+and Co3+, and x is the mole fraction having integral value ranging from 0.2 to 0.33, and z is the number of water molecules and ranges from 1 to 4, useful as, a catalyst, and a process for the preparation thereof and use thereof to manufacture vicinal diols.

Asymmetric dihydroxylation onto the α,β-unsaturated carboxylic ester derivatives of camptothecin

Dihydroxyalkanoic ester derivatives (4a,b) and (5a,b) of 20S-camptothecin (1) were diastereoselectively synthesized by exploiting osmium-catalyzed asymmetric dihydroxylation based on the Sharpless procedure. The absolute configuration of the newly formed

Multipolymer-supported substrate and ligand approach to the sharpless asymmetric dihydroxylation

The correct combination of soluble and insoluble polymers allows a multipolymer reaction in which the substrate trans-cinnamate and the chiral ligand are bound to different polymer supports. The reactions (shown schematically on the right) proceed with 98

Reactions of Trialkylsilyl Trifluoromethanesulfonates VII. - α-Trimethylsiloxycarboxylation by Tris(trimethylsiloxy)ethene.

In the presence of trimethylsilyl triflate (1), acetals and orthocarboxylic acid esters 3 react with tris(trimethylsiloxy)ethene 2 to yield 3-alkoxy- and 3,3-dialkoxy-2-(trimethylsiloxy)carboxylates 4.From carbonyl compounds 6 and the ketene acetal 2 2,3-

Kinetics and Mechanism of the Oxidation of Unsaturated Carboxylic Acids by Methyltributylammonium Permanganate in Methylene Chloride Solutions

The product obtained when permanganate is reduced by unsaturated carboxylic acids under anhydrous conditions is manganese(III).The rate of reaction, which is subject to acid catalysis, exhibits a Hammet ρ value of 1.11 and inverse secondary isotope effects (kH/kD = 0.96-0.98) when the hydrogens on the double bond are replaced by deuterium.The involvement of a free-radical process is indicated by the formation of polymer during the oxidation of acrylic and methacrylic acids.The reaction is believed to be initiated by formation of an organometallic complex in which the double bond is a η2 ligand on manganese.Rearrangement of this complex results in the formation of a reactive manganate(V) cyclic diester, which undergoes a rapid (free-radical) reduction to manganese(III).